Detalhe da pesquisa
1.
Novel bicyclo[3.1.0]hexane analogs as antagonists of metabotropic glutamate 2/3 receptors for the treatment of depression.
Bioorg Med Chem Lett
; 26(23): 5663-5668, 2016 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27836401
2.
Discovery of (1R,2R)-N-(4-(6-isopropylpyridin-2-yl)-3-(2-methyl-2H-indazol-5-yl)isothiazol-5-yl)-2-methylcyclopropanecarboxamide, a potent and orally efficacious mGlu5 receptor negative allosteric modulator.
Bioorg Med Chem Lett
; 23(5): 1249-52, 2013 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23374867
3.
Discovery of (1S,2R,3S,4S,5R,6R)-2-Amino-3-[(3,4-difluorophenyl)sulfanylmethyl]-4-hydroxy-bicyclo[3.1.0]hexane-2,6-dicarboxylic Acid Hydrochloride (LY3020371·HCl): A Potent, Metabotropic Glutamate 2/3 Receptor Antagonist with Antidepressant-Like Activity.
J Med Chem
; 59(24): 10974-10993, 2016 12 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-28002967
4.
Identification of a nonsteroidal liver X receptor agonist through parallel array synthesis of tertiary amines.
J Med Chem
; 45(10): 1963-6, 2002 May 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-11985463