Detalhe da pesquisa
1.
In Vitro Metabolite Formation in Human Hepatocytes and Cardiomyocytes and Metabolism and Tissue Distribution in Monkeys of the 2'-C-Methylguanosine Prodrug BMS-986094 : Potential Role in Clinical Cardiovascular Toxicity.
Int J Toxicol
; 36(1): 35-49, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28056568
2.
Fluid shear stress modulation of hepatocyte-like cell function.
Arch Toxicol
; 90(7): 1757-61, 2016 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-26979076
3.
BMS-986001, an HIV nucleoside reverse transcriptase inhibitor, does not degrade mitochondrial DNA in long-term primary cultures of cells isolated from human kidney, muscle, and adipose tissue.
Antimicrob Agents Chemother
; 57(12): 6205-12, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24080659
4.
Cytochrome P450 11A1 bioactivation of a kinase inhibitor in rats: use of radioprofiling, modulation of metabolism, and adrenocortical cell lines to evaluate adrenal toxicity.
Chem Res Toxicol
; 25(3): 556-71, 2012 Mar 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-22295996
5.
Dimethyl fumarate reduces hepatocyte senescence following paracetamol exposure.
iScience
; 24(6): 102552, 2021 Jun 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-34151225
6.
The role of protease inhibitors in the pathogenesis of HIV-associated lipodystrophy: cellular mechanisms and clinical implications.
Toxicol Pathol
; 37(1): 65-77, 2009 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-19171928
7.
Combining stem cell-derived hepatocytes with impedance sensing to better predict human drug toxicity.
Expert Opin Drug Metab Toxicol
; 15(1): 77-83, 2019 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-30572740
8.
Discovery of dapagliflozin: a potent, selective renal sodium-dependent glucose cotransporter 2 (SGLT2) inhibitor for the treatment of type 2 diabetes.
J Med Chem
; 51(5): 1145-9, 2008 Mar 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-18260618
9.
Notes on the pleasing lacewing genus Dilar Rambur, 1838 (Neuroptera, Dilaridae), with description of a new species from Vietnam.
Zootaxa
; 4425(1): 193-200, 2018 May 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-30313476
10.
Description of adults and immature stages of Antipodoecia Mosely from Australia and synonymy of the families Antipodoeciidae and Anomalopsychidae (Insecta: Trichoptera).
Zootaxa
; 4532(1): 125-136, 2018 Dec 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-30647379
11.
Effects of atazanavir/ritonavir and lopinavir/ritonavir on glucose uptake and insulin sensitivity: demonstrable differences in vitro and clinically.
AIDS
; 20(14): 1813-21, 2006 Sep 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-16954722
12.
Effects of BMS-986094, a Guanosine Nucleotide Analogue, on Mitochondrial DNA Synthesis and Function.
Toxicol Sci
; 153(2): 396-408, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27466212
13.
The Trichoptera barcode initiative: a strategy for generating a species-level Tree of Life.
Philos Trans R Soc Lond B Biol Sci
; 371(1702)2016 09 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-27481793
14.
Polyurethane: Stable Cell Phenotype Requires Plasticity: Polymer Supported Directed Differentiation Reveals a Unique Gene Signature Predicting Stable Hepatocyte Performance (Adv. Healthcare Mater. 12/2015).
Adv Healthc Mater
; 4(12): 1819, 2015 Aug 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-26308957
15.
Polymer Supported Directed Differentiation Reveals a Unique Gene Signature Predicting Stable Hepatocyte Performance.
Adv Healthc Mater
; 4(12): 1820-5, 2015 Aug 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-26109270
16.
Accurate prediction of drug-induced liver injury using stem cell-derived populations.
Stem Cells Transl Med
; 3(2): 141-8, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24375539
17.
Establishment of a molecular embryonic stem cell developmental toxicity assay.
Toxicol Sci
; 131(2): 447-57, 2013 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-23042729
18.
New fossil Lepidoptera (Insecta: Amphiesmenoptera) from the Middle Jurassic Jiulongshan Formation of Northeastern China.
PLoS One
; 8(11): e79500, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-24278142
19.
Developing high-fidelity hepatotoxicity models from pluripotent stem cells.
Stem Cells Transl Med
; 2(7): 505-9, 2013 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-23757504
20.
Discovery of a Novel Class of Bicyclo[3.1.0]hexanylpiperazines as Noncompetitive Neuropeptide Y Y1 Antagonists.
ACS Med Chem Lett
; 3(3): 222-6, 2012 Mar 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-24900458