Detalhe da pesquisa
1.
A SCID Mouse Model To Evaluate the Efficacy of Antivirals against SARS-CoV-2 Infection.
J Virol
; 96(16): e0075822, 2022 08 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-35924921
2.
A dual-antigen self-amplifying RNA SARS-CoV-2 vaccine induces potent humoral and cellular immune responses and protects against SARS-CoV-2 variants through T cell-mediated immunity.
Mol Ther
; 30(9): 2968-2983, 2022 09 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35450821
3.
New 2-Ethylthio-4-methylaminoquinazoline derivatives inhibiting two subunits of cytochrome bc1 in Mycobacterium tuberculosis.
PLoS Pathog
; 16(1): e1008270, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31971990
4.
Molnupiravir Inhibits Replication of the Emerging SARS-CoV-2 Variants of Concern in a Hamster Infection Model.
J Infect Dis
; 224(5): 749-753, 2021 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34244768
5.
ALG-097111, a potent and selective SARS-CoV-2 3-chymotrypsin-like cysteine protease inhibitor exhibits in vivo efficacy in a Syrian Hamster model.
Biochem Biophys Res Commun
; 555: 134-139, 2021 05 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-33813272
6.
Optimized Background Regimen for Treatment of Active Tuberculosis with the Next-Generation Benzothiazinone Macozinone (PBTZ169).
Antimicrob Agents Chemother
; 62(11)2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30126954
7.
Structure-Based Drug Design and Characterization of Sulfonyl-Piperazine Benzothiazinone Inhibitors of DprE1 from Mycobacterium tuberculosis.
Antimicrob Agents Chemother
; 62(10)2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30012754
8.
Mapping the testicular interstitial fluid proteome from normal rats.
Proteomics
; 16(17): 2391-402, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27324652
9.
Characterization of DprE1-Mediated Benzothiazinone Resistance in Mycobacterium tuberculosis.
Antimicrob Agents Chemother
; 60(11): 6451-6459, 2016 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27527085
10.
Conditional expression of Parkinson's disease-related R1441C LRRK2 in midbrain dopaminergic neurons of mice causes nuclear abnormalities without neurodegeneration.
Neurobiol Dis
; 71: 345-58, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25174890
11.
Integrating artificial intelligence-based epitope prediction in a SARS-CoV-2 antibody discovery pipeline: caution is warranted.
EBioMedicine
; 100: 104960, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38232633
12.
Androgen initiates Sertoli cell tight junction formation in the hypogonadal (hpg) mouse.
Biol Reprod
; 87(2): 38, 2012 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-22623623
13.
Ivermectin Does Not Protect against SARS-CoV-2 Infection in the Syrian Hamster Model.
Microorganisms
; 10(3)2022 Mar 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-35336208
14.
The omicron (B.1.1.529) SARS-CoV-2 variant of concern does not readily infect Syrian hamsters.
Antiviral Res
; 198: 105253, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35066015
15.
Updated vaccine protects against SARS-CoV-2 variants including Omicron (B.1.1.529) and prevents transmission in hamsters.
Nat Commun
; 13(1): 6644, 2022 11 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36333374
16.
The oral protease inhibitor (PF-07321332) protects Syrian hamsters against infection with SARS-CoV-2 variants of concern.
Nat Commun
; 13(1): 719, 2022 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35169114
17.
HIV protease inhibitors Nelfinavir and Lopinavir/Ritonavir markedly improve lung pathology in SARS-CoV-2-infected Syrian hamsters despite lack of an antiviral effect.
Antiviral Res
; 202: 105311, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35390430
18.
Potent neutralizing anti-SARS-CoV-2 human antibodies cure infection with SARS-CoV-2 variants in hamster model.
iScience
; 25(8): 104705, 2022 Aug 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-35813873
19.
Patient-derived monoclonal antibody neutralizes SARS-CoV-2 Omicron variants and confers full protection in monkeys.
Nat Microbiol
; 7(9): 1376-1389, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35879526
20.
Need for a Standardized Translational Drug Development Platform: Lessons Learned from the Repurposing of Drugs for COVID-19.
Microorganisms
; 10(8)2022 Aug 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36014057