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1.
J Shoulder Elbow Surg ; 31(8): e363-e368, 2022 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-35183743

RESUMO

BACKGROUND AND HYPOTHESIS: Although shoulder and elbow injuries in professional baseball players have been thoroughly studied, little is known about the frequency and impact of pectoralis muscle injuries in this population. The purpose of this study was to use the official league injury surveillance system to describe pectoralis muscle injuries in professional baseball players in Major League Baseball (MLB) and Minor League Baseball (MiLB). Specifically, (1) player demographic characteristics, (2) return to play (RTP), (3) injury mechanism, (4) throwing- and batting-side dominance, and (5) injury rate per athlete exposure (AE) were characterized to guide future injury prevention strategies. METHODS: The MLB Health and Injury Tracking System database was used to compile all pectoralis muscle injuries in MLB and MiLB athletes in the 2011-2017 seasons. Injury-related data including diagnosis (tear or rupture vs. strain), player demographic characteristics, injury timing, need for surgical intervention, RTP, and mechanism of injury were recorded. Subanalyses of throwing- and batting-side dominance, as well as MLB vs. MiLB injury frequency, were performed. RESULTS: A total of 138 pectoralis muscle injuries (32 MLB and 106 MiLB injuries) were reported in the study period (5 tears or ruptures and 133 strains), with 5 of these being recurrent injuries. Operative intervention was performed in 4 athletes (2.9%). Of the 138 injuries, 116 (84.1%) resulted in missed days of play, with a mean time to RTP of 19.5 days. Starting pitchers sustained the greatest proportion of pectoralis injuries (48.1%), with pitching being the most common activity at the time of injury (45.9%). A majority of injuries (86.5%) were sustained during non-contact play. Overall, 87.5% of injuries occurred on the player's dominant throwing side and 81.3% occurred on the player's dominant batting side. There was no significant difference in the rate of pectoralis injuries in the MLB regular season (0.584 per 10,000 AEs) vs. the MiLB regular season (0.425 per 10,000 AEs) (P = .1018). CONCLUSION: Pectoralis muscle injuries are most frequently non-contact injuries, most commonly sustained by pitchers. An understanding of these injuries can guide athletic trainers and management in expectation management and decision making, in addition to directing future efforts at injury prevention.


Assuntos
Traumatismos do Braço , Traumatismos em Atletas , Beisebol , Atletas , Traumatismos em Atletas/epidemiologia , Beisebol/lesões , Humanos , Músculos Peitorais/lesões
2.
J Shoulder Elbow Surg ; 30(1): 127-133, 2021 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-32778383

RESUMO

BACKGROUND: Shoulder injuries account for a large portion of all recorded injuries in professional baseball. Much is known about other shoulder pathologies in the overhead athlete, but the incidence and impact of acromioclavicular (AC) joint injuries in this population are unknown. We examined the epidemiology of AC joint injuries in Major League Baseball (MLB) and Minor League Baseball (MiLB) players and determined the impact on time missed. METHODS: The MLB Health and Injury Tracking System was used to compile records of all MLB and MiLB players from 2011 to 2017 with documented AC joint injuries. These injuries were classified as acute (sprain or separation) or chronic (AC joint arthritis or distal clavicular osteolysis), and associated data extracted included laterality, date of injury, player position, activity, mechanism of injury, length of return to play, and need for surgical intervention. RESULTS: A total of 312 AC joint injuries (183 in MiLB players and 129 in MLB players; range, 39-60 per year) were recorded: 201 acute (64.4%) and 111 chronic (35.6%). A total of 81% of acute and 59% of chronic injuries resulted in time missed, with a mean length of return to play of 21 days for both. Of the injuries in outfielders, 79.6% were acute (P < .0001), as were 66.3% of injuries in infielders (P = .004). Pitchers and catchers had more equal proportions of acute and chronic AC injuries (P > .05 for all). Acute AC injuries occurred most often while fielding (n = 100, 84.7%), running (n = 25, 80.6%), and hitting (n = 19, 61.3%), whereas chronic injuries tended to be more common while pitching (n = 26, 68.4%). Of contact injuries, 82.5% were acute (P < .0001), whereas 59.0% of noncontact injuries were chronic (P = .047). MLB players showed consistently higher regular-season rates of both acute and chronic AC injuries than MiLB players (P < .0001 for each). CONCLUSION: Acute AC joint injuries are contact injuries occurring most commonly among infielders and outfielders while fielding that result in 3 weeks missed before return to play, whereas chronic AC joint injuries occur more commonly in pitchers and catchers from noncontact repetitive overhead activity. Knowledge of these data can better guide expectation management in this elite population to better elucidate the prevalence of 2 common injury patterns in the AC joint.


Assuntos
Articulação Acromioclavicular , Traumatismos em Atletas , Beisebol , Atletas , Traumatismos em Atletas/epidemiologia , Humanos , Incidência
3.
J Shoulder Elbow Surg ; 28(6): 1159-1165, 2019 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-30827835

RESUMO

BACKGROUND: A recently introduced classification of medial ulnar collateral ligament (UCL) tears has demonstrated high interobserver and intraobserver reliability, but little is known about its prognostic utility. The purpose of this study was to assess the relationship of the magnetic resonance imaging (MRI)-based classification system and nonoperative vs. operative management. Secondary objectives included subanalysis of baseball players. METHODS: Eighty-five consecutive patients with UCL tears after a standardized treatment paradigm were categorized as operative vs. nonoperative. UCL tears of patients with a minimum of 1-year follow-up were retrospectively classified using the MRI-based classification system. Subanalyses for baseball players included return-to-play and return-to-prior performance. RESULTS: A total of 80 patients (62 baseball players, 54 pitchers) met inclusion criteria. A total of 51 patients underwent surgery, and 29 patients completed nonoperative management. In baseball players, 59% of the proximal tears were treated nonoperatively and 97% of the distal tears were treated operatively; 100% of the proximal partial-thickness tears and 100% of the distal complete tears were treated nonoperatively and operatively, respectively. Patients with distal (odds ratio: 48.4, P < .0001) and complete (odds ratio: 5.0, P = .004) tears were more likely to undergo surgery. Baseball players, regardless of position, were determinants of operative management, and there was no difference in return-to-play clearance and return-to-prior performance between the operative and nonoperative groups. CONCLUSION: A reliable 6-stage MRI-based classification addressing UCL tear grade and location may confer decision making between operative and nonoperative management. Complete and distal tears carry a markedly increased risk of failing nonoperative care compared with proximal, partial tears.


Assuntos
Traumatismos em Atletas/classificação , Traumatismos em Atletas/diagnóstico por imagem , Beisebol/lesões , Ligamento Colateral Ulnar/diagnóstico por imagem , Ligamento Colateral Ulnar/lesões , Articulação do Cotovelo/diagnóstico por imagem , Imageamento por Ressonância Magnética , Adulto , Traumatismos em Atletas/terapia , Tomada de Decisão Clínica , Ligamento Colateral Ulnar/cirurgia , Tratamento Conservador , Articulação do Cotovelo/cirurgia , Seguimentos , Humanos , Prognóstico , Estudos Retrospectivos , Adulto Jovem
4.
J Shoulder Elbow Surg ; 27(11): 2068-2076, 2018 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-30076036

RESUMO

BACKGROUND: Recent anatomic and clinical studies have shown that the location of the injury to the elbow ulnar collateral ligament (UCL) is an important variable in deciding on surgical intervention; however, no studies have evaluated these findings biomechanically. METHODS: This study tested 16 intact elbow specimens. Valgus torques of 2.5 and 5 Nm were applied to the elbow at various flexion angles, and the resulting valgus angles were measured. The valgus angles were applied to the elbows in their intact states and again after partial and complete cuts were made on the proximal and distal insertions of the UCL. Resulting valgus torques were measured, and stiffness was calculated for each elbow flexion angle. Unpaired t tests were used to evaluate the effects of cut location and flexion angle on joint rotational stability and stiffness. RESULTS: The posterior-distal insertion contributed the most to stability. At valgus angles generated from 2.5 Nm intact torques, the posterior-distal insertions contributed to 51% ± 26% (P < .03) intact rotational stability, and at valgus angles generated from 5 Nm intact torques, the posterior-distal insertions contributed to 41% ± 17% (P < .02) intact rotational stability. For overall stiffness, the posterior-distal insertions contributed to 31% ± 12% (P < .045) intact stiffness. CONCLUSION: Overall, the posterior distal insertion of the UCL contributed most to rotational stability and stiffness of the medial elbow when subjected to valgus stress at 90° and 120° of elbow flexion. At higher elbow flexion angles, the posterior insertions contributed more to stability, whereas the anterior insertions had a greater effect at lower flexion angles.


Assuntos
Ligamento Colateral Ulnar/lesões , Articulação do Cotovelo , Instabilidade Articular/etiologia , Idoso , Fenômenos Biomecânicos , Cadáver , Humanos , Instabilidade Articular/fisiopatologia , Masculino , Pessoa de Meia-Idade , Amplitude de Movimento Articular , Torque , Suporte de Carga
5.
J Shoulder Elbow Surg ; 27(2): 211-216, 2018 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-29037535

RESUMO

BACKGROUND: Diagnosing infection after shoulder arthroplasty can be a challenge because of the high prevalence of low-virulence organisms, such as Propionibacterium acnes. The purpose of this study was to evaluate the utility of implant sonication fluid cultures in the diagnosis of periprosthetic joint infection compared with standard culture techniques in patients undergoing revision shoulder arthroplasty. METHODS: Routine perioperative testing was performed in 53 patients who underwent revision shoulder arthroplasty. In addition to routine tissue and fluid culture, the retrieved shoulder implants underwent sonication with culture of the sonicate fluid. Diagnostic performance of implant sonication culture was determined on the basis of previously defined infection criteria and compared with standard intraoperative cultures. RESULTS: Of the 53 revision cases that underwent implant sonication fluid culture, 25 (47%) were classified as infected. Intraoperative culture (tissue and fluid) sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy were 96%, 75%, 77%, 95%, and 85%, respectively. Using a cutoff of >20 colony-forming units per milliliter to exclude contaminants, the sensitivity, specificity, PPV, NPV, and accuracy of implant sonicate culture were 56% (P < .001, compared with standard intraoperative cultures), 93% (P = .07), 88% (P = .4), 70% (P = .02), and 75% (P = .22), respectively. Without use of a sonication fluid culture cutoff value, the sensitivity, specificity, PPV, NPV, and accuracy of implant sonicate culture were 96% (P = 1.0, compared with standard intraoperative cultures), 64% (P = .38), 71% (P = .53), 95% (P = .9), and 79% (P = .45). CONCLUSIONS: Implant sonication fluid culture in revision shoulder arthroplasty showed no significant benefits over standard intraoperative cultures in diagnostic utility for periprosthetic joint infection.


Assuntos
Artrite Infecciosa/diagnóstico , Artroplastia do Ombro/efeitos adversos , Infecções por Bactérias Gram-Positivas/diagnóstico , Propionibacterium acnes/isolamento & purificação , Infecções Relacionadas à Prótese/diagnóstico , Sonicação/métodos , Infecção da Ferida Cirúrgica/diagnóstico , Adulto , Idoso , Idoso de 80 Anos ou mais , Artrite Infecciosa/microbiologia , Artrite Infecciosa/prevenção & controle , Feminino , Infecções por Bactérias Gram-Positivas/microbiologia , Infecções por Bactérias Gram-Positivas/prevenção & controle , Humanos , Masculino , Pessoa de Meia-Idade , Infecções Relacionadas à Prótese/microbiologia , Infecções Relacionadas à Prótese/prevenção & controle , Curva ROC , Articulação do Ombro/cirurgia , Infecção da Ferida Cirúrgica/microbiologia , Infecção da Ferida Cirúrgica/prevenção & controle
6.
J Shoulder Elbow Surg ; 26(2): 186-196, 2017 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-27720413

RESUMO

BACKGROUND: Periprosthetic joint infection (PJI) after shoulder arthroplasty can present a diagnostic and therapeutic challenge. This study evaluated the diagnostic utility of broader synovial fluid cytokine analysis for identifying PJI in patients undergoing revision shoulder arthroplasty. METHODS: Synovial fluid levels of 9 cytokines (interleukin [IL] 6, granulocyte-macrophage colony-stimulating factor, IL-1ß, IL-12, IL-2, IL-8, interferon-γ, IL-10, and tumor necrosis factor-α) were measured in 75 cases of revision shoulder arthroplasty with a multiplex immunoassay. Cases were classified into infection categories and groups based on objective perioperative findings. Differences in cytokine levels among infection groups were evaluated. Receiver operating characteristic curves were used to assess the diagnostic utility of the individual synovial fluid cytokines and combinations of cytokines in determining infection status. RESULTS: Synovial IL-6, granulocyte-macrophage colony-stimulating factor, interferon-γ, IL-1ß, IL-2, IL-8, and IL-10 were significantly elevated in cases of revision shoulder arthroplasty classified as infected. Individually, IL-6, IL-1ß, IL-8, and IL-10 showed the best combination of sensitivity and specificity for predicting infection, and a combined cytokine model consisting of IL-6, tumor necrosis factor-α, and IL-2 showed better diagnostic test characteristics than any cytokine alone, with sensitivity of 0.80, specificity of 0.93,, positive and negative predictive values of 0.87 and 0.89, and positive and negative likelihood ratios of 12.0 and 0.21. CONCLUSIONS: Individual and combined synovial fluid cytokine analysis were both more effective than routine perioperative testing, such as serum erythrocyte sedimentation rate and C-reactive protein, in the diagnosis of PJI of the shoulder. Once validated, combined synovial fluid cytokine analysis could be used as a predictive tool to determine the probability of PJI in patients undergoing revision shoulder arthroplasty and better guide treatment.


Assuntos
Artrite Infecciosa/diagnóstico , Artroplastia do Ombro/efeitos adversos , Citocinas/metabolismo , Infecções Relacionadas à Prótese/diagnóstico , Articulação do Ombro , Adulto , Idoso , Idoso de 80 Anos ou mais , Artrite Infecciosa/metabolismo , Biomarcadores/metabolismo , Proteína C-Reativa/metabolismo , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Prospectivos , Infecções Relacionadas à Prótese/metabolismo , Reoperação , Sensibilidade e Especificidade , Líquido Sinovial/química
7.
Clin Orthop Relat Res ; 474(7): 1630-9, 2016 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-26821163

RESUMO

BACKGROUND: Diagnosing periprosthetic joint infection (PJI) requires a combination of clinical and laboratory parameters, which may be expensive and difficult to interpret. Synovial fluid cytokines have been shown to accurately differentiate septic from aseptic failed total knee (TKA) and hip (THA) arthroplasties. However, after first-stage explantation, there is still no reliable test to rule out PJI before a second-stage reimplantation procedure. QUESTIONS/PURPOSES: (1) Which synovial fluid cytokines have the highest diagnostic accuracy for PJI? (2) Which cytokine shows the greatest decrease associated with the resolution of infection in the same patient between explantation and subsequent reimplantation of an infected arthroplasty? (3) What is the accuracy of synovial fluid cytokines and the Musculoskeletal Infection Society (MSIS) criteria to rule out PJI after first-stage explantation? (4) What are the most studied synovial fluid cytokines for diagnosing PJI as reported in the literature and what are their cumulative diagnostic accuracy? METHODS: Between May 2013 and March 2014, 104 patients with painful THA and TKA evaluated for possible PJI were included in our study. Of these, 90 (87%) had cytokine levels measured from synovial fluid samples collected as part of this prospective study (n = 33 hips, n = 57 knees). A second group of 35 patients (n = 36 samples) who presented during the same time period with an antibiotic spacer also had synovial cytokines measured before second-stage reimplantation. For the first group of 90 patients, the MSIS definition classified each joint at the time of surgery as infected (n = 31) or not infected (n = 59) and was used as the standard to test the accuracy in diagnosing PJI. Of the 35 patients with synovial marker data before second-stage surgery, 15 patients had cytokine measurements both at explantation and reimplantation and were used to quantify the change between stages. The reimplantation group had a minimum 1-year followup (with four [11%] patients lost to followup) and was classified into successful or failed treatment based on Delphi-based consensus data and was used to test the accuracy in detecting infection resolution at reimplantation. RESULTS: Interleukin (IL)-1ß and interferon-γ demonstrated the highest diagnostic utility (area under the curve 0.92, 0.91, respectively); IL-1ß and IL-6 had the highest sensitivities (0.90 [95% confidence interval {CI}, 0.74-0.98] and 0.81 [0.63-0.93]). As a measure of infection resolution, IL-1ß had the greatest decrease (12.4-fold; level at explantation: 232.4 [range, 23.1-1545.7]; level at reimplantation: 18.8 (range 1.2-298.9); mean difference: 325.5 [95% CI, 65.0-596.0]; p = 0.0001), and IL-6 had a nearly similar decrease (11.2-fold; level at explantation: 228.1 [range, 10,158.4-182,725.0]; level at reimplantation: 2518.2 [range, 10.4-41,319.3]; mean difference: 33,176.0 [95% CI, 7543.6-58,808.3]; p < 0.0001). Cytokines and MSIS criteria had low sensitivity to rule out infection in a joint treated for PJI. CONCLUSIONS: IL-6 and IL-1ß demonstrated high sensitivities to diagnose PJI and showed the greatest decrease between first and second stages, which may potentially be used to monitor treatment response to PJI. However, cytokines and MSIS criteria had low sensitivity to rule out infection before reimplantation. LEVEL OF EVIDENCE: Level III, diagnostic study.


Assuntos
Artroplastia de Quadril/efeitos adversos , Artroplastia do Joelho/efeitos adversos , Citocinas/metabolismo , Remoção de Dispositivo , Prótese de Quadril/efeitos adversos , Prótese do Joelho/efeitos adversos , Infecções Relacionadas à Prótese/cirurgia , Líquido Sinovial/metabolismo , Adulto , Idoso , Idoso de 80 Anos ou mais , Antibacterianos/uso terapêutico , Área Sob a Curva , Artroplastia de Quadril/instrumentação , Artroplastia do Joelho/instrumentação , Biomarcadores/metabolismo , Técnica Delphi , Feminino , Humanos , Interleucina-1beta/metabolismo , Interleucina-6/metabolismo , Masculino , Pessoa de Meia-Idade , Valor Preditivo dos Testes , Estudos Prospectivos , Infecções Relacionadas à Prótese/diagnóstico , Infecções Relacionadas à Prótese/metabolismo , Infecções Relacionadas à Prótese/microbiologia , Curva ROC , Reoperação , Fatores de Risco , Líquido Sinovial/microbiologia , Fatores de Tempo , Resultado do Tratamento
8.
Clin Orthop Relat Res ; 474(7): 1610-5, 2016 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-26864855

RESUMO

BACKGROUND: Previous studies have demonstrated that the administration of antibiotics to patients before performing diagnostic testing for periprosthetic joint infection (PJI) can interfere with the accuracy of test results. Although a single-institution study has suggested that alpha-defensin maintains its concentration and sensitivity even after antibiotic treatment, this has not yet been demonstrated in a larger multiinstitutional study. QUESTIONS/PURPOSES: (1) For the evaluation of PJI, is prior antibiotic administration associated with decreased alpha-defensin levels? (2) When prior antibiotics are given, is alpha-defensin a better screening test for PJI than the traditional tests (erythrocyte sedimentation rate [ESR], C-reactive protein [CRP], fluid white blood cells, fluid polymorphonuclear cells [PMNs], and fluid culture)? METHODS: This retrospective study included data from 106 hip and knee arthroplasties with Musculoskeletal Infection Society-defined PJI from four centers. Of the 106 patients in this study, 30 (28%) were treated with antibiotics for PJI before diagnostic workup (ABX group), and 76 (72%) were not treated before the diagnostic workup (NO-ABX group). There were no differences in age, sex, joint, culture-negative rate, or bacteriology between groups. The patients in the ABX group had antibiotics initiated by physicians who commenced care before assessment for PJI by the treating surgeon's service. We compared the alpha-defensin levels and sensitivity between the ABX and NO-ABX groups. Additionally, the sensitivity of the alpha-defensin test was compared to that of traditional tests for PJI among patients on antibiotics. RESULTS: The administration of antibiotics before performing the alpha-defensin test for PJI was not associated with a decreased median alpha-defensin level (ABX group, median 4.2 [range, 1.79-12.8 S/CO] versus NO-ABX, median 4.9 [range, 0.5-16.8 S/CO], difference of medians: 0.68 S/CO [95% confidence interval {CI}, -0.98 to 1.26], p = 0.451). Furthermore, the alpha-defensin test had a higher sensitivity (100%; 95% CI, 88.4%-100.0%) in diagnosing PJI among patients on antibiotics when compared with the ESR (69.0% [95% CI, 49.17%-84.72%], p = 0.001), the CRP (79.3% [95% CI, 60.3%-92.0%], p = 0.009), the fluid PMN% (79.3% [95% CI, 60.3%-92.0%), p = 0.009), and fluid culture (70.0% [95% CI, 50.6%-85.3%], p = 0.001). CONCLUSIONS: The alpha-defensin test maintains its concentration and sensitivity for PJI even in the setting of antibiotic administration. Furthermore, among patients with PJI on antibiotics, the alpha-defensin tests demonstrated a higher sensitivity in detecting PJI when compared with the ESR, CRP, fluid PMN%, and fluid culture. The high sensitivity of the alpha-defensin test, even in the setting of prior antibiotic treatment, provides excellent utility as a screening test for PJI. LEVEL OF EVIDENCE: Level III, diagnostic study.


Assuntos
Antibacterianos/administração & dosagem , Antibioticoprofilaxia , Artroplastia de Quadril/efeitos adversos , Artroplastia do Joelho/efeitos adversos , Infecção Hospitalar/diagnóstico , Prótese de Quadril/efeitos adversos , Prótese do Joelho/efeitos adversos , Infecções Relacionadas à Prótese/diagnóstico , alfa-Defensinas/metabolismo , Adulto , Idoso , Idoso de 80 Anos ou mais , Artroplastia de Quadril/instrumentação , Artroplastia do Joelho/instrumentação , Biomarcadores/metabolismo , Infecção Hospitalar/metabolismo , Infecção Hospitalar/microbiologia , Infecção Hospitalar/prevenção & controle , Esquema de Medicação , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Valor Preditivo dos Testes , Infecções Relacionadas à Prótese/metabolismo , Infecções Relacionadas à Prótese/microbiologia , Infecções Relacionadas à Prótese/prevenção & controle , Reprodutibilidade dos Testes , Estudos Retrospectivos , Líquido Sinovial/metabolismo , Líquido Sinovial/microbiologia , Resultado do Tratamento , Estados Unidos
9.
J Arthroplasty ; 31(2): 456-60, 2016 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-26545577

RESUMO

BACKGROUND: The purpose of this study was to test the accuracy of a single synovial fluid biomarker, α-defensin, in diagnosing periprosthetic joint infection in revision total hip and revision total knee arthroplasty. METHODS: A total of 102 patients comprising 116 revision total hip arthroplasty and revision total knee arthroplasty procedures performed between May 2013 and March 2014 were prospectively evaluated. Cases were categorized as infected or notinfected using Musculoskeletal Infection Society criteria. Synovial fluid was obtained and tested for α-defensin using a commercially available kit (Synovasure [CD Diagnostics, Baltimore, Maryland]). RESULTS: For first-stage and single-stage revisions, the α-defensin test had a sensitivity of 100% (95% confidence interval [CI], 86%-100%) and a specificity of 98% (95% CI, 90%-100%) with a positive predictive value of 96% (95% CI, 80%-99%) and negative predictive value of 100% (95% CI, 93%-100%). CONCLUSION: A positive α-defensin test result was significantly more sensitive and specific for predicting infection than current diagnostic testing and should be considered when managing periprosthetic joint infection. LEVEL OF EVIDENCE: Level III, Study of Diagnostic Test.


Assuntos
Artroplastia de Quadril/efeitos adversos , Artroplastia do Joelho/efeitos adversos , Infecções Relacionadas à Prótese/diagnóstico , alfa-Defensinas/análise , Idoso , Artrite Infecciosa/diagnóstico , Biomarcadores/análise , Proteína C-Reativa/análise , Testes Diagnósticos de Rotina , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Valor Preditivo dos Testes , Estudos Prospectivos , Reoperação , Sensibilidade e Especificidade , Líquido Sinovial/química
10.
J Shoulder Elbow Surg ; 24(7): 1021-7, 2015 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-25672257

RESUMO

BACKGROUND: Diagnosis of periprosthetic joint infection (PJI) in revision shoulder arthroplasty can be challenging because of the indolent nature of the common offending organisms. The purpose of this study was to evaluate the diagnostic utility of synovial fluid α-defensin levels in identifying PJI of the shoulder. METHODS: Thirty patients evaluated for painful shoulder arthroplasty were prospectively enrolled and underwent revision surgery (n = 33 cases). Cases were categorized into infection (n = 11) and no-infection (n = 22) groups on the basis of preoperative and intraoperative findings. Synovial fluid was obtained from preoperative aspirations or intraoperative aspiration before arthrotomy. α-Defensin was tested by the Synovasure (CD Diagnostics, Wynnewood, PA, USA) test for joint infection. Synovial fluid was also obtained intraoperatively from a control group undergoing arthroscopic rotator cuff repair (n = 16) for baseline data on normal α-defensin levels in the shoulder. A receiver operating characteristic curve was used to determine the diagnostic utility of synovial fluid α-defensin. RESULTS: Synovial α-defensin had an area under the curve, sensitivity, specificity, and positive and negative likelihood ratios of 0.78, 63%, 95%, 12.1, and 0.38, respectively. There was a significant difference in α-defensin levels between the infection (median, 3.2 S/CO [signal to cutoff ratio]) and no-infection groups (median, 0.21 S/CO; P = .006). Synovial α-defensin was elevated in the presence of a culture positive for Propionibacterium acnes (median, 1.33 S/CO; P = .03) and showed moderate correlation with the number of positive cultures. CONCLUSION: Synovial fluid α-defensin was more effective than current diagnostic testing in predicting positive cultures and may be an effective adjunct in the workup of shoulder PJI.


Assuntos
Artroplastia de Substituição , Infecções Relacionadas à Prótese/diagnóstico , Articulação do Ombro/cirurgia , Líquido Sinovial/metabolismo , alfa-Defensinas/metabolismo , Biomarcadores/metabolismo , Feminino , Humanos , Funções Verossimilhança , Masculino , Pessoa de Meia-Idade , Valor Preditivo dos Testes , Estudos Prospectivos , Sensibilidade e Especificidade , Articulação do Ombro/microbiologia
11.
J Shoulder Elbow Surg ; 23(9): 1277-81, 2014 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-24725902

RESUMO

BACKGROUND: Infection after shoulder arthroplasty can present a diagnostic challenge. The purpose of this study was to evaluate the utility of serum interleukin-6 (IL-6) levels in diagnosis of periprosthetic infection in patients undergoing revision shoulder arthroplasty. METHODS: We prospectively enrolled 69 patients who underwent revision shoulder arthroplasty at one institution. All patients underwent a standard preoperative and intraoperative workup for infection, which included shoulder aspirate culture, erythrocyte sedimentation rate, C-reactive protein level, tissue culture, and frozen section analysis. In addition, serum levels of IL-6 were measured preoperatively in all patients. Infection classification was divided into 4 groups, (1) definite, (2) probable, (3) possible, and (4) no infection, on the basis of previously reported criteria using intraoperative cultures and preoperative and intraoperative findings of infections. RESULTS: Of the 69 patients, 24 were classified as having a definite or probable infection. Propionibacterium acnes was the offending organism for the majority of these cases (20 of 24, 83%). IL-6 was not a sensitive marker of infection for these patients (sensitivity: 3 of 24, 12%; specificity: 3 of 45, 93%). The sensitivity of serum IL-6 was lower compared with erythrocyte sedimentation rate (sensitivity: 10 of 24, 42%; specificity: 37 of 45, 82%) and C-reactive protein level (sensitivity: 11 of 24, 46%; specificity: 42 of 45, 93%). For the non-P. acnes cases (1 Staphylococcus aureus, 1 Enterobacter cloacae, 2 coagulase-negative Staphylococcus species), the sensitivity of IL-6 was 25% (1 of 4). CONCLUSION: Serum IL-6 is not an effective marker for diagnosis of infection in shoulder arthroplasty. On the basis of this large prospective study, we do not recommend its use as a preoperative diagnostic test in patients undergoing revision shoulder arthroplasty.


Assuntos
Artroplastia de Substituição/efeitos adversos , Interleucina-6/sangue , Infecções Relacionadas à Prótese/sangue , Infecções Relacionadas à Prótese/diagnóstico , Adulto , Idoso , Idoso de 80 Anos ou mais , Biomarcadores/sangue , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Valor Preditivo dos Testes , Estudos Prospectivos , Infecções Relacionadas à Prótese/microbiologia , Reoperação , Articulação do Ombro/microbiologia , Articulação do Ombro/cirurgia
12.
Shoulder Elbow ; 16(1): 15-23, 2024 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-38435042

RESUMO

Background: The purpose of this study was to systematically review the rate and timing of return to play in overhead athletes following operative management of anterior shoulder instability. Methods: A systematic literature search based on PRISMA guidelines, utilizing the EMBASE, MEDLINE, and The Cochrane Library Databases. Eligible for inclusion were clinical studies reporting on return to play among overhead athletes following arthroscopic Bankart repair, open Latarjet procedure or Remplissage procedure. Results: There are 23 studies included with 961 patients. Among those undergoing arthroscopic Bankart repair, the rate of return to play was 86.2%, with 70.6% returning to the same level of play and the mean time to return to play was 7.1 months. Among those undergoing an open Latarjet procedure, the rate of return to play was 80.9%, with 77.7% returning to the same level of play and the mean time to return to play was 5.1 months. Among those undergoing a Remplissage procedure, the rate of return to play was 70.6%, with 70.0% returning to the same level of play or mean time to return to play. Discussion: Overall, there were high rates of return to play following operative management of anterior shoulder instability in overhead athletes.

13.
Sports Health ; : 19417381241226896, 2024 Feb 19.
Artigo em Inglês | MEDLINE | ID: mdl-38374636

RESUMO

CONTEXT: Interest in the relationship between psychology and the outcomes of anterior cruciate ligament (ACL) reconstruction (ACLR) continues to grow as variable rates of return to preinjury level of activity continue to be observed. EVIDENCE ACQUISITION: Articles were collected from peer-reviewed sources available on PubMed using a combination of search terms, including psychology, resilience, mental health, recovery, and anterior cruciate ligament reconstruction. Further evaluation of the included bibliographies were used to expand the evidence. STUDY DESIGN: Clinical review. LEVEL OF EVIDENCE: Level 4. RESULTS: General mental health and wellbeing, in addition to a host of unique psychological traits (self-efficacy, resilience, psychological readiness and distress, pain catastrophizing, locus of control, and kinesiophobia) have been demonstrated convincingly to affect treatment outcomes. Moreover, compelling evidence suggests that a number of these traits may be modifiable. Although the effect of resilience on outcomes of orthopaedic surgical procedures has been studied extensively, there is very limited information linking this unique psychological trait to the outcomes of ACLR. Similarly, the available information related to other parameters, such as pain catastrophizing, is limited with respect to the existence of adequately sized cohorts capable of accommodating more rigorous and compelling analyses. A better understanding of the specific mechanisms through which psychological traits influence outcomes can inform future interventions intended to improve rates of return to preinjury level of activity after ACLR. CONCLUSION: The impact of psychology on patients' responses to ACL injury and treatment represents a promising avenue for improving low rates of return to preinjury activity levels among certain cohorts. Future research into these areas should focus on specific effects of targeted interventions on known, modifiable risk factors that commonly contribute to suboptimal clinical outcomes. STRENGTH-OF-RECOMMENDATION TAXONOMY (SORT): B.

14.
Arthrosc Sports Med Rehabil ; 6(2): 100812, 2024 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-38379604

RESUMO

Purpose: To determine whether low resilience is predictive of worse patient-reported outcomes (PROs) or diminished improvements in clinical outcomes after joint preserving and arthroscopic surgery. Methods: A comprehensive search of PubMed, Medline, Embase, and Science Direct was performed on September 28, 2022, for studies investigating the relationship between resilience and PROs after arthroscopic surgery in accordance with the Preferred Reported Items for Systematic Reviews and Meta-analyses guidelines. Results: Nine articles (level II-IV studies) were included in the final analysis. A total of 887 patients (54% male, average age 45 years) underwent arthroscopic surgery, including general knee (n = 3 studies), ACLR-only knee (n = 1 study), rotator cuff repair (n = 4 studies), and hip (n = 1 study). The Brief Resilience Scale was the most common instrument measuring resilience in 7 of 9 studies (78%). Five of 9 studies (56%) stratified patients based on high, normal, or low resilience cohorts, and these stratification threshold values differed between studies. Only 4 of 9 studies (44%) measured PROs both before and after surgery. Three of 9 studies (33%) reported rates of return to activity, with 2 studies (22%) noting high resilience to be associated with a higher likelihood of return to sport/duty, specifically after knee arthroscopy. However, significant associations between resilience and functional outcomes were not consistently observed, nor was resilience consistently observed to be predictive of subjects' capacity to return to a preinjury level of function. Conclusions: Patient resilience is inconsistently demonstrated to affect clinical outcomes associated with joint preserving and arthroscopic surgery. However, substantial limitations in the existing literature including underpowered sample sizes, lack of standardization in stratifying patients based on pretreatment resilience, and inconsistent collection of PROs throughout the continuum of care, diminish the strength of most conclusions that have been drawn. Level of Evidence: Level IV, systematic review of level II-IV studies.

15.
Orthop J Sports Med ; 12(4): 23259671231204014, 2024 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-38646604

RESUMO

Background: Surgeon performance has been investigated as a factor affecting patient outcomes after orthopaedic procedures to improve transparency between patients and providers. Purpose/Hypothesis: The purpose of this study was to identify whether surgeon performance influenced patient-reported outcomes (PROMs) 1 year after arthroscopic partial meniscectomy (APM). It was hypothesized that there would be no significant difference in PROMs between patients who underwent APM from various surgeons. Study Design: Case-control study; Level of evidence, 3. Methods: A prospective cohort of 794 patients who underwent APM between 2018 and 2019 were included in the analysis. A total of 34 surgeons from a large multicenter health care center were included. Three multivariable models were built to determine whether the surgeon-among demographic and meniscal pathology factors-was a significant variable for predicting the Knee injury and Osteoarthritis Outcome Score (KOOS)-Pain subscale, the Patient Acceptable Symptom State (PASS), and a 10-point improvement in the KOOS-Pain at 1 year after APM. Likelihood ratio (LR) tests were used to determine the significance of the surgeon variable in the models. Results: The 794 patients were identified from the multicenter hospital system. The baseline KOOS-Pain score was a significant predictor of outcome in the 1-year KOOS-Pain model (odds ratio [OR], 2.1 [95% CI, 1.77-2.48]; P < .001), the KOOS-Pain 10-point improvement model (OR, 0.57 [95% CI, 0.44-0.73), and the 1-year PASS model (OR, 1.42 [95% CI, 1.15-1.76]; P = .002) among articular cartilage pathology (bipolar medial cartilage) and patient-factor variables, including body mass index, Veterans RAND 12-Item Health Survey-Mental Component Score, and Area Deprivation Index. The individual surgeon significantly impacted outcomes in the 1-year KOOS-Pain mixed model in the LR test (P = .004). Conclusion: Patient factors and characteristics are better predictors for patient outcomes 1 year after APM than surgeon characteristics, specifically baseline KOOS-Pain, although an individual surgeon influenced the 1-Year KOOS-Pain mixed model in the LR test. This finding has key clinical implications; surgeons who wish to improve patient outcomes after APM should focus on improving patient selection rather than improving the surgical technique. Future research is needed to determine whether surgeon variability has an impact on longer-term patient outcomes.

16.
Sports Health ; : 19417381231179970, 2023 Jun 16.
Artigo em Inglês | MEDLINE | ID: mdl-37326165

RESUMO

BACKGROUND: Athletes who are well prepared for the physical demands of competition are less susceptible to injury. Defining and then preparing athletes for these in-game demands is critical to athlete health and performance. The injury burden within Major League Baseball (MLB) is significant and differs by position. Despite its importance, the workload demands have not been described for position players in MLB. HYPOTHESIS: That running demands would be significantly higher for outfielders, followed by infielders, and catchers, respectively, while batting and baserunning metrics would be similar across positions. STUDY DESIGN: Cohort study. LEVEL OF EVIDENCE: Level 3. METHODS: Total and high-speed running distance (>75% Vmax), high-speed running count, hard accelerations (>2.78 m/s/s), defensive and baserunning minutes, total and hard throws (>75% max), and bat swing counts were calculated from Statcast data. Players with 100 games or more in the 2018 season (n = 126) were included for analysis. RESULTS: All offensive and baserunning metrics were similar across positions; however, significant positional differences were observed for defensive and overall workload metrics. High-speed running was highest among outfielders (F1,7 = 27.1, P < 0.01), followed by infielders, then catchers. Hard accelerations (F1,7 = 12.9, P < 0.01) were highest among first basemen, then outfielders, remaining infielders, and catchers. Total throws (F1,7 = 17.7, P < 0.01) were highest among middle infielders. Hard throws (P < 0.01) were highest among shortstops and third basemen. CONCLUSION: In-game workloads differ significantly by defensive position in MLB. These differences in running, throwing, and hitting volumes have significant implications for physical preparation and injury return-to-play progressions to optimize performance and minimize injury and reinjury risk for these athletes. CLINICAL RELEVANCE: These data provide insight into how best to prepare athletes of different positions for the demands of the game both in terms of preseason preparation as well as return-to-play benchmarks following injury. These data should also serve as a platform for future research into the relationship between workload and injury among professional baseball players.

17.
J Shoulder Elbow Surg ; 21(6): 765-71, 2012 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-22305919

RESUMO

BACKGROUND: Structural allografts have been used for management of large defects of the glenoid. We describe a surgical technique for graft preparation and the radiographic and clinical results of a series of patients using this technique. MATERIALS AND METHODS: In 19 consecutive patients, a polymethyl methacrylate mold was used to shape a single graft from a fresh-frozen femoral head to press fit within the glenoid defect. We evaluated the clinical and radiographic results with a minimum 2-year follow-up or until revision to another total shoulder replacement. RESULTS: Six patients showed more than 50% resorption of the graft. Four of these six patients also had less than 50% graft incorporation, and these findings were associated with a less favorable clinical outcome. In 3 of 6 cases in which poly-L-lactic acid bioresorbable screws were used, a significant giant cell reaction was noted at the time of revision surgery. Seven of nine patients with metal screw fixation had bent, broken, or worn screws because of graft collapse and contact with the prosthetic humeral head. Four of the five revision cases that were converted to a reverse total shoulder replacement had sufficient bone incorporation and volume of bone to allow for secure glenoid and screw fixation. CONCLUSION: The surgical technique described is useful in creation of a well-fitting graft. The amount of bone resorption and bone incorporation and clinical outcome have wide variability. In those cases where revision was performed with another total shoulder replacement, there was sufficient bone incorporation and sufficient bone mass to allow component fixation.


Assuntos
Artroplastia de Substituição/métodos , Transplante Ósseo/métodos , Fêmur/transplante , Articulação do Ombro/cirurgia , Artrite Reumatoide/cirurgia , Cimentos Ósseos , Humanos , Polimetil Metacrilato , Radiografia , Reoperação , Articulação do Ombro/diagnóstico por imagem , Transplante Homólogo
18.
Am J Sports Med ; 50(9): 2481-2487, 2022 07.
Artigo em Inglês | MEDLINE | ID: mdl-35833921

RESUMO

BACKGROUND: Elite pitchers have demonstrated significant differences in glenohumeral range of motion and humeral torsion compared with the nonthrowing population. Furthermore, abnormal shoulder range of motion measurements have been associated with different injury risks and challenges in assessing rehabilitation progress. Variations in range of motion and torsion due to handedness in the asymptomatic professional population have yet to be investigated in the literature. HYPOTHESIS: No significant differences in glenohumeral range of motion and humeral torsion would exist between asymptomatic right- and left-handed professional pitchers. STUDY DESIGN: Cross-sectional study; Level of evidence, 3. METHODS: 217 Major League Baseball pitchers from a single organization were evaluated over a 7-year period between 2013 and 2020. Range of motion was measured with a standard goniometer. Ultrasound scanning was used to determine neutral position of the shoulder, and the degree of humeral torsion was measured with a goniometer. RESULTS: Right-handed pitchers demonstrated significantly greater values of glenohumeral external rotation (118.5° vs 112.7°; P < .001) in their throwing arms compared with their left-handed counterparts. Right-handed pitchers also showed greater values of glenohumeral internal rotation deficit (13.9° vs 4.8°; P < .001) and side-to-side differences in humeral retrotorsion (-23.1° vs -2.2°; P < .001). Left-handed pitchers demonstrated significantly greater flexion deficits in the throwing arm compared with their right-handed counterparts (7.5° vs 0.0°; P < .001). CONCLUSION: In the throwing arm, right-handed pitchers demonstrated significantly greater measures of external rotation, glenohumeral internal rotation deficit, and humeral retrotorsion compared with left-handed counterparts. Furthermore, right-handed pitchers demonstrated a significant side-to-side difference in retrotorsion, whereas left-handed pitchers did not. However, left-handed pitchers demonstrated a side-to-side shoulder flexion deficit that was not present in the cohort of right-handed pitchers. The correlation between humeral retrotorsion and increased external rotation indicates that osseous adaptations may play a role in range of motion differences associated with handedness. Additionally, these findings may explain observed differences in several throwing metrics between right- and left-handed pitchers. Knowledge of these differences can inform rehabilitation programs and shoulder maintenance regimens.


Assuntos
Beisebol , Articulação do Ombro , Beisebol/lesões , Estudos Transversais , Humanos , Úmero/diagnóstico por imagem , Amplitude de Movimento Articular , Articulação do Ombro/diagnóstico por imagem
20.
JSES Rev Rep Tech ; 1(4): 295-300, 2021 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-37588704

RESUMO

Given the rising incidence and prevalence of shoulder injuries in throwing athletes, this review aims to evaluate management options and outcomes of common shoulder injuries in overhead throwers. Laxity of the glenohumeral joint is often adaptive for overhead athletes to achieve the velocity necessary to compete in the professional ranks. Surgical repair of the stabilizers of the humeral head-specifically the labrum and rotator cuff-often causes inflammation, scarring, and overtensioning of the glenohumeral joint which lead to poor postoperative performance. Thus, nonsurgical management should be exhausted in this population before considering surgical intervention.

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