Detalhe da pesquisa
1.
The ACE inhibitor captopril inhibits ACN-1 to control dauer formation and aging.
Development
; 151(3)2024 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38284547
2.
Acetyl-CoA-mediated autoacetylation of fatty acid synthase as a metabolic switch of de novo lipogenesis in Drosophila.
Proc Natl Acad Sci U S A
; 119(49): e2212220119, 2022 12 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36459649
3.
Parasitic nematode fatty acid- and retinol-binding proteins compromise host immunity by interfering with host lipid signaling pathways.
PLoS Pathog
; 17(10): e1010027, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34714893
4.
A human iPSC-derived inducible neuronal model of Niemann-Pick disease, type C1.
BMC Biol
; 19(1): 218, 2021 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34592985
5.
19q13.12 microdeletion syndrome fibroblasts display abnormal storage of cholesterol and sphingolipids in the endo-lysosomal system.
Biochim Biophys Acta Mol Basis Dis
; 1864(6 Pt A): 2108-2118, 2018 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29580926
6.
Targeting the mitochondrial pyruvate carrier attenuates fibrosis in a mouse model of nonalcoholic steatohepatitis.
Hepatology
; 65(5): 1543-1556, 2017 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28027586
7.
A HILIC-MS/MS method for simultaneous quantification of the lysosomal disease markers galactosylsphingosine and glucosylsphingosine in mouse serum.
Biomed Chromatogr
; 32(7): e4235, 2018 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-29516569
8.
A New Glucocerebrosidase Chaperone Reduces α-Synuclein and Glycolipid Levels in iPSC-Derived Dopaminergic Neurons from Patients with Gaucher Disease and Parkinsonism.
J Neurosci
; 36(28): 7441-52, 2016 07 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-27413154
9.
Glucocerebrosidase haploinsufficiency in A53T α-synuclein mice impacts disease onset and course.
Mol Genet Metab
; 122(4): 198-208, 2017 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-29173981
10.
A murine Niemann-Pick C1 I1061T knock-in model recapitulates the pathological features of the most prevalent human disease allele.
J Neurosci
; 35(21): 8091-106, 2015 May 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-26019327
11.
Cholesterol homeostatic responses provide biomarkers for monitoring treatment for the neurodegenerative disease Niemann-Pick C1 (NPC1).
Hum Mol Genet
; 23(22): 6022-33, 2014 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24964810
12.
Altered distribution and function of natural killer cells in murine and human Niemann-Pick disease type C1.
Blood
; 123(1): 51-60, 2014 Jan 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-24235134
13.
A novel intrinsically fluorescent probe for study of uptake and trafficking of 25-hydroxycholesterol.
J Lipid Res
; 56(12): 2408-19, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26497473
14.
Tracking the subcellular fate of 20(s)-hydroxycholesterol with click chemistry reveals a transport pathway to the Golgi.
J Biol Chem
; 289(16): 11095-11110, 2014 Apr 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-24596093
15.
Development and validation of sensitive LC-MS/MS assays for quantification of HP-ß-CD in human plasma and CSF.
J Lipid Res
; 55(7): 1537-48, 2014 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-24868096
16.
Palmitate and lipopolysaccharide trigger synergistic ceramide production in primary macrophages.
J Biol Chem
; 288(5): 2923-32, 2013 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23250746
17.
Identification of Niemann-Pick C1 disease biomarkers through sphingolipid profiling.
J Lipid Res
; 54(10): 2800-14, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23881911
18.
Modulation of cellular S1P levels with a novel, potent and specific inhibitor of sphingosine kinase-1.
Biochem J
; 444(1): 79-88, 2012 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22397330
19.
Isolation and Mass Spectrometry-Based Profiling of Major Lipids in Brown Adipose Tissue.
Methods Mol Biol
; 2662: 219-239, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37076685
20.
The ACE-inhibitor drug captopril inhibits ACN-1 to control dauer formation and aging.
bioRxiv
; 2023 Jul 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-37502959