Detalhe da pesquisa
1.
Alpha-synuclein aggregates activate calcium pump SERCA leading to calcium dysregulation.
EMBO Rep
; 19(5)2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29599149
2.
Caspase-1 causes truncation and aggregation of the Parkinson's disease-associated protein α-synuclein.
Proc Natl Acad Sci U S A
; 113(34): 9587-92, 2016 08 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-27482083
3.
The degree of astrocyte activation in multiple system atrophy is inversely proportional to the distance to α-synuclein inclusions.
Mol Cell Neurosci
; 65: 68-81, 2015 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-25731829
4.
Generation and characterization of novel conformation-specific monoclonal antibodies for α-synuclein pathology.
Neurobiol Dis
; 79: 81-99, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25937088
5.
Non-neuronal and neuronal BACE1 elevation in association with angiopathic and leptomeningeal ß-amyloid deposition in the human brain.
BMC Neurol
; 15: 71, 2015 May 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-25934480
6.
Evidence that the LRRK2 ROC domain Parkinson's disease-associated mutants A1442P and R1441C exhibit increased intracellular degradation.
J Neurosci Res
; 92(4): 506-16, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24375786
7.
Amyloid beta1â42 (Aß42) up-regulates the expression of sortilin via the p75(NTR)/RhoA signaling pathway.
J Neurochem
; 127(2): 152-62, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23895422
8.
Intraneuronal sortilin aggregation relative to granulovacuolar degeneration, tau pathogenesis and sorfra plaque formation in human hippocampal formation.
Front Aging Neurosci
; 14: 926904, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35978952
9.
Phosphorylation at S87 is enhanced in synucleinopathies, inhibits alpha-synuclein oligomerization, and influences synuclein-membrane interactions.
J Neurosci
; 30(9): 3184-98, 2010 Mar 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-20203178
10.
Changes in the solubility and phosphorylation of α-synuclein over the course of Parkinson's disease.
Acta Neuropathol
; 121(6): 695-704, 2011 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-21400129
11.
Real-time analysis of amyloid fibril formation of alpha-synuclein using a fibrillation-state-specific fluorescent probe of JC-1.
Biochem J
; 418(2): 311-23, 2009 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19007333
12.
NSF, Unc-18-1, dynamin-1 and HSP90 are inclusion body components in neuronal intranuclear inclusion disease identified by anti-SUMO-1-immunocapture.
Acta Neuropathol
; 116(6): 603-14, 2008 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-18836734
13.
LRRK2 and parkin immunoreactivity in multiple system atrophy inclusions.
Acta Neuropathol
; 116(6): 639-46, 2008 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-18936941
14.
Molecular characterization of a novel dipeptidyl peptidase like 2-short form (DPL2-s) that is highly expressed in the brain and lacks dipeptidyl peptidase activity.
Biochim Biophys Acta
; 1764(1): 33-43, 2006 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-16290253
15.
Axonal dystrophy in the brain of mice with Sanfilippo syndrome.
Exp Neurol
; 295: 243-255, 2017 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28601604
16.
Proteomic analysis of Myrmecia pilosula (jack jumper) ant venom.
Toxicon
; 47(2): 208-17, 2006 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-16376960
17.
Neuroprotective Activities of Marine Natural Products from Marine Sponges.
Curr Med Chem
; 23(4): 360-82, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-26630920
18.
Interference of α-Synuclein Uptake by Monomeric ß-Amyloid1-40 and Potential Core Acting Site of the Interference.
Neurotox Res
; 30(3): 479-85, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27364697
19.
Quantitative protein profiling of hippocampus during human aging.
Neurobiol Aging
; 39: 46-56, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-26923401
20.
Annular alpha-synuclein oligomers are potentially toxic agents in alpha-synucleinopathy. Hypothesis.
Neurotox Res
; 7(1-2): 59-67, 2005.
Artigo
em Inglês
| MEDLINE | ID: mdl-15639798