Detalhe da pesquisa
1.
TopBP1 interacts with BLM to maintain genome stability but is dispensable for preventing BLM degradation.
Mol Cell
; 57(6): 1133-1141, 2015 Mar 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-25794620
2.
Loss of Cyclin C or CDK8 provides ATR inhibitor resistance by suppressing transcription-associated replication stress.
Nucleic Acids Res
; 49(15): 8665-8683, 2021 09 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34329458
3.
RNF4, a SUMO-targeted ubiquitin E3 ligase, promotes DNA double-strand break repair.
Genes Dev
; 26(11): 1179-95, 2012 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22661229
4.
The N-terminal Region of Chromodomain Helicase DNA-binding Protein 4 (CHD4) Is Essential for Activity and Contains a High Mobility Group (HMG) Box-like-domain That Can Bind Poly(ADP-ribose).
J Biol Chem
; 291(2): 924-38, 2016 Jan 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-26565020
5.
The COP9 signalosome is vital for timely repair of DNA double-strand breaks.
Nucleic Acids Res
; 43(9): 4517-30, 2015 May 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-25855810
6.
Mammalian SUMO E3-ligases PIAS1 and PIAS4 promote responses to DNA double-strand breaks.
Nature
; 462(7275): 935-9, 2009 Dec 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-20016603
7.
The SUMO modification pathway is involved in the BRCA1 response to genotoxic stress.
Nature
; 462(7275): 886-90, 2009 Dec 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-20016594
8.
Regulation of DNA-damage responses and cell-cycle progression by the chromatin remodelling factor CHD4.
EMBO J
; 29(18): 3130-9, 2010 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20693977
9.
Chromatin relaxation in response to DNA double-strand breaks is modulated by a novel ATM- and KAP-1 dependent pathway.
Nat Cell Biol
; 8(8): 870-6, 2006 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-16862143
10.
RAD54L2 counters TOP2-DNA adducts to promote genome stability.
Sci Adv
; 9(49): eadl2108, 2023 12 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-38055822
11.
Chronic irradiation of human cells reduces histone levels and deregulates gene expression.
Sci Rep
; 10(1): 2200, 2020 02 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32042076
12.
Small-Molecule Inhibition of UBE2T/FANCL-Mediated Ubiquitylation in the Fanconi Anemia Pathway.
ACS Chem Biol
; 14(10): 2148-2154, 2019 10 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-31525021
13.
ATM orchestrates the DNA-damage response to counter toxic non-homologous end-joining at broken replication forks.
Nat Commun
; 10(1): 87, 2019 01 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30622252
14.
Predicting the mutations generated by repair of Cas9-induced double-strand breaks.
Nat Biotechnol
; 2018 Nov 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-30480667
15.
Shieldin complex promotes DNA end-joining and counters homologous recombination in BRCA1-null cells.
Nat Cell Biol
; 20(8): 954-965, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30022119
16.
Synthetic lethality between androgen receptor signalling and the PARP pathway in prostate cancer.
Nat Commun
; 8(1): 374, 2017 08 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-28851861
17.
Ubiquitination capabilities in response to neocarzinostatin and H(2)O(2) stress in cell lines from patients with ataxia-telangiectasia.
Oncogene
; 21(28): 4363-73, 2002 Jun 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-12080467
18.
Systematic E2 screening reveals a UBE2D-RNF138-CtIP axis promoting DNA repair.
Nat Cell Biol
; 17(11): 1458-1470, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26502057
19.
Neddylation promotes ubiquitylation and release of Ku from DNA-damage sites.
Cell Rep
; 11(5): 704-14, 2015 May 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-25921528
20.
CtIP tetramer assembly is required for DNA-end resection and repair.
Nat Struct Mol Biol
; 22(2): 150-157, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25558984