Detalhe da pesquisa
1.
The American lifestyle-induced obesity syndrome diet in male and female rodents recapitulates the clinical and transcriptomic features of nonalcoholic fatty liver disease and nonalcoholic steatohepatitis.
Am J Physiol Gastrointest Liver Physiol
; 319(3): G345-G360, 2020 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32755310
2.
Increased central adiposity and decreased subcutaneous adipose tissue 11ß-hydroxysteroid dehydrogenase type 1 are associated with deterioration in glucose tolerance-A longitudinal cohort study.
Clin Endocrinol (Oxf)
; 91(1): 72-81, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30667079
3.
11ß-HSD1 is the major regulator of the tissue-specific effects of circulating glucocorticoid excess.
Proc Natl Acad Sci U S A
; 111(24): E2482-91, 2014 Jun 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-24889609
4.
Glucagon-like peptide 1 decreases lipotoxicity in non-alcoholic steatohepatitis.
J Hepatol
; 64(2): 399-408, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-26394161
5.
Advanced non-alcoholic fatty liver disease and adipose tissue fibrosis in patients with Alström syndrome.
Liver Int
; 36(11): 1704-1712, 2016 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27178444
6.
Dehydroepiandrosterone exerts antiglucocorticoid action on human preadipocyte proliferation, differentiation, and glucose uptake.
Am J Physiol Endocrinol Metab
; 305(9): E1134-44, 2013 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24022868
7.
11ß-HSD1 contributes to age-related metabolic decline in male mice.
J Endocrinol
; 255(3): 117-129, 2022 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36205523
8.
Acute intermittent hypoxia drives hepatic de novo lipogenesis in humans and rodents.
Metabol Open
; 14: 100177, 2022 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-35313531
9.
AKR1D1 knockout mice develop a sex-dependent metabolic phenotype.
J Endocrinol
; 253(3): 97-113, 2022 04 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-35318963
10.
Differential activity and expression of human 5ß-reductase (AKR1D1) splice variants.
J Mol Endocrinol
; 66(3): 181-194, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33502336
11.
Glucocorticoids regulate AKR1D1 activity in human liver in vitro and in vivo.
J Endocrinol
; 245(2): 207-218, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32106090
12.
Human and murine steroid 5ß-reductases (AKR1D1 and AKR1D4): insights into the role of the catalytic glutamic acid.
Chem Biol Interact
; 305: 163-170, 2019 May 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-30928400
13.
AKR1D1 regulates glucocorticoid availability and glucocorticoid receptor activation in human hepatoma cells.
J Steroid Biochem Mol Biol
; 189: 218-227, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30769091
14.
AKR1D1 is a novel regulator of metabolic phenotype in human hepatocytes and is dysregulated in non-alcoholic fatty liver disease.
Metabolism
; 99: 67-80, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31330134
15.
Glucocorticoid modulation of insulin signaling in human subcutaneous adipose tissue.
J Clin Endocrinol Metab
; 92(11): 4332-9, 2007 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-17711920
16.
Male 11ß-HSD1 Knockout Mice Fed Trans-Fats and Fructose Are Not Protected From Metabolic Syndrome or Nonalcoholic Fatty Liver Disease.
Endocrinology
; 157(9): 3493-504, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27384305
17.
5α-Reductase Type 2 Regulates Glucocorticoid Action and Metabolic Phenotype in Human Hepatocytes.
Endocrinology
; 156(8): 2863-71, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-25974403
18.
Hormonal regulation of lipogenesis.
Vitam Horm
; 91: 1-27, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23374710
19.
11ß-Hydroxysteroid dehydrogenase 1: translational and therapeutic aspects.
Endocr Rev
; 34(4): 525-55, 2013 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-23612224
20.
Glucocorticoids fail to cause insulin resistance in human subcutaneous adipose tissue in vivo.
J Clin Endocrinol Metab
; 98(4): 1631-40, 2013 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-23426618