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IEEE Trans Biomed Eng ; 48(10): 1080-7, 2001 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-11585031

RESUMO

A new method based on a multiresolution approach for solving the ill-posed problem of brain electrical activity reconstruction from electroencephaloram (EEG)/magnetoencephalogram (MEG) signals is proposed in a distributed source model. At each step of the algorithm, a regularized solution to the inverse problem is used to constrain the source space on the cortical surface to be scanned at higher spatial resolution. We present the iterative procedure together with an extension of the ST-maximum a posteriori method [1] that integrates spatial and temporal a priori information in an estimator of the brain electrical activity. Results from EEG in a phantom head experiment with a real human skull and from real MEG data on a healthy human subject are presented. The performances of the multiresolution method combined with a nonquadratic estimator are compared with commonly used dipolar methods, and to minimum-norm method with and without multiresolution. In all cases, the proposed approach proved to be more efficient both in terms of computational load and result quality, for the identification of sparse focal patterns of cortical current density, than the fixed scale imaging approach.


Assuntos
Eletroencefalografia , Processamento de Imagem Assistida por Computador , Magnetoencefalografia , Algoritmos , Estimulação Elétrica , Humanos , Modelos Neurológicos , Imagens de Fantasmas , Processamento de Sinais Assistido por Computador
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