Detalhe da pesquisa
1.
RIPK1 kinase-dependent inflammation and cell death contribute to the pathogenesis of COPD.
Eur Respir J
; 61(4)2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36549711
2.
An intestinal organoid-based platform that recreates susceptibility to T-cell-mediated tissue injury.
Blood
; 135(26): 2388-2401, 2020 06 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-32232483
3.
Insulin-like growth factor 2 (IGF2) protects against Huntington's disease through the extracellular disposal of protein aggregates.
Acta Neuropathol
; 140(5): 737-764, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32642868
4.
Pharmacologic inhibition of ghrelin receptor signaling is insulin sparing and promotes insulin sensitivity.
J Pharmacol Exp Ther
; 339(1): 115-24, 2011 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-21775475
5.
Characterization of the insulin sensitivity of ghrelin receptor KO mice using glycemic clamps.
BMC Physiol
; 11: 1, 2011 Jan 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-21211044
6.
Stage-Dependent Impact of RIPK1 Inhibition on Atherogenesis: Dual Effects on Inflammation and Foam Cell Dynamics.
Front Cardiovasc Med
; 8: 715337, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34760938
7.
Ubiquitylation of MLKL at lysine 219 positively regulates necroptosis-induced tissue injury and pathogen clearance.
Nat Commun
; 12(1): 3364, 2021 06 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34099649
8.
The 24-hour respiratory quotient predicts energy intake and changes in body mass.
Am J Physiol Regul Integr Comp Physiol
; 298(3): R747-54, 2010 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-20018821
9.
Enhanced gastrointestinal motility with orally active ghrelin receptor agonists.
J Pharmacol Exp Ther
; 329(3): 1178-86, 2009 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-19252061
10.
Discovery and Lead-Optimization of 4,5-Dihydropyrazoles as Mono-Kinase Selective, Orally Bioavailable and Efficacious Inhibitors of Receptor Interacting Protein 1 (RIP1) Kinase.
J Med Chem
; 62(10): 5096-5110, 2019 05 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-31013427
11.
Improved insulin sensitivity and metabolic flexibility in ghrelin receptor knockout mice.
Regul Pept
; 150(1-3): 55-61, 2008 Oct 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-18453014
12.
Discovery and characterization of aminopiperidinecoumarin melanin concentrating hormone receptor 1 antagonists.
J Med Chem
; 48(19): 5888-91, 2005 Sep 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-16161992
13.
Central effects of long-term relaxin expression in the rat.
Ann N Y Acad Sci
; 1041: 216-22, 2005 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-15956711
14.
Adenovirus-mediated expression of human prorelaxin promotes the invasive potential of canine mammary cancer cells.
Endocrinology
; 144(8): 3683-91, 2003 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-12865351
15.
The prolactin-releasing peptide receptor (GPR10) regulates body weight homeostasis in mice.
J Mol Neurosci
; 22(1-2): 93-103, 2004.
Artigo
em Inglês
| MEDLINE | ID: mdl-14742914
16.
Daily energy balance in growth hormone receptor/binding protein (GHR -/-) gene-disrupted mice is achieved through an increase in dark-phase energy efficiency.
Growth Horm IGF Res
; 20(1): 73-9, 2010 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-19747867
17.
Identification of aminopiperidine benzamides as MCHr1 antagonists.
Bioorg Med Chem Lett
; 15(14): 3412-6, 2005 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-15950463
18.
CARD-8 protein, a new CARD family member that regulates caspase-1 activation and apoptosis.
J Biol Chem
; 277(16): 13952-8, 2002 Apr 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-11821383
19.
PYPAF1, a PYRIN-containing Apaf1-like protein that assembles with ASC and regulates activation of NF-kappa B.
J Biol Chem
; 277(13): 11570-5, 2002 Mar 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-11786556
20.
PYPAF7, a novel PYRIN-containing Apaf1-like protein that regulates activation of NF-kappa B and caspase-1-dependent cytokine processing.
J Biol Chem
; 277(33): 29874-80, 2002 Aug 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-12019269