Detalhe da pesquisa
1.
Development and evaluation of 4-(pyrrolidin-3-yl)benzonitrile derivatives as inhibitors of lysine specific demethylase 1.
Bioorg Med Chem Lett
; 27(20): 4755-4759, 2017 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28927796
2.
Development of 5-hydroxypyrazole derivatives as reversible inhibitors of lysine specific demethylase 1.
Bioorg Med Chem Lett
; 27(14): 3190-3195, 2017 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28545974
3.
Structural basis of ligand recognition in 5-HT3 receptors.
EMBO Rep
; 14(1): 49-56, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23196367
4.
Mechanistic and kinetic characterization of hepatitis C virus NS3 protein interactions with NS4A and protease inhibitors.
J Mol Recognit
; 24(1): 60-70, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-21194118
5.
A protein interaction node at the neurotransmitter release site: domains of Aczonin/Piccolo, Bassoon, CAST, and rim converge on the N-terminal domain of Munc13-1.
J Neurosci
; 29(40): 12584-96, 2009 Oct 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-19812333
6.
Interaction kinetic and structural dynamic analysis of ligand binding to acetylcholine-binding protein.
Biochemistry
; 49(37): 8143-54, 2010 Sep 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-20701394
7.
Structural and functional analysis of hepatitis C virus strain JFH1 polymerase.
J Virol
; 83(22): 11926-39, 2009 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-19740982
8.
Development of surface plasmon resonance biosensor assays for primary and secondary screening of acetylcholine binding protein ligands.
Anal Biochem
; 407(1): 58-64, 2010 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20599657
9.
Macrocyclic Peptides Uncover a Novel Binding Mode for Reversible Inhibitors of LSD1.
ACS Omega
; 5(8): 3979-3995, 2020 Mar 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32149225
10.
Screening for NNRTIs with slow dissociation and high affinity for a panel of HIV-1 RT variants.
J Biomol Screen
; 14(4): 395-403, 2009 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-19403922
11.
Development of (4-Cyanophenyl)glycine Derivatives as Reversible Inhibitors of Lysine Specific Demethylase 1.
J Med Chem
; 60(19): 7984-7999, 2017 10 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-28892629
12.
Biosensor-based kinetic characterization of the interaction between HIV-1 reverse transcriptase and non-nucleoside inhibitors.
J Med Chem
; 49(8): 2367-74, 2006 Apr 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-16610780
13.
Interaction kinetic characterization of HIV-1 reverse transcriptase non-nucleoside inhibitor resistance.
J Med Chem
; 49(8): 2375-87, 2006 Apr 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-16610781
14.
Identification and Characterization of an Irreversible Inhibitor of CDK2.
Chem Biol
; 22(9): 1159-64, 2015 Sep 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-26320860
15.
Deconstruction of non-nucleoside reverse transcriptase inhibitors of human immunodeficiency virus type 1 for exploration of the optimization landscape of fragments.
J Med Chem
; 54(3): 709-18, 2011 Feb 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-21207958
16.
Identification of a novel scaffold for allosteric inhibition of wild type and drug resistant HIV-1 reverse transcriptase by fragment library screening.
J Med Chem
; 54(3): 699-708, 2011 Feb 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-21207961
17.
Experimental validation of a fragment library for lead discovery using SPR biosensor technology.
J Biomol Screen
; 16(1): 15-25, 2011 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-21149860
18.
Surface plasmon resonance biosensor based fragment screening using acetylcholine binding protein identifies ligand efficiency hot spots (LE hot spots) by deconstruction of nicotinic acetylcholine receptor α7 ligands.
J Med Chem
; 53(19): 7192-201, 2010 Oct 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-20828128
19.
Additional level of information about complex interaction between non-nucleoside inhibitor and HIV-1 reverse transcriptase using biosensor-based thermodynamic analysis.
Bioorg Med Chem
; 15(23): 7344-54, 2007 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17870544
20.
Biomolecular recognition of glycosylated beta(3)-peptides by GalNAc specific lectins.
J Mol Recognit
; 20(2): 132-8, 2007.
Artigo
em Inglês
| MEDLINE | ID: mdl-17410519