Pesquisa | BVS IEC

1.

Say Cheese: Structure of the Cardiac Electrical Engine Is Captured.

Ghovanloo, Mohammad-Reza; Ruben, Peter C.

Trends Biochem Sci ; 45(5): 369-371, 2020 05.

Artigo em Inglês | MEDLINE | ID: mdl-32311330

2.

Nav1.7 P610T mutation in two siblings with persistent ocular pain after corneal axon transection: impaired slow inactivation and hyperexcitable trigeminal neurons.

Ghovanloo, Mohammad-Reza; Effraim, Philip R; Yuan, Jun-Hui; Schulman, Betsy R; Jacobs, Deborah S; Dib-Hajj, Sulayman D; Waxman, Stephen G.

J Neurophysiol ; 129(3): 609-618, 2023 03 01.

Artigo em Inglês | MEDLINE | ID: mdl-36722722

3.

Late sodium current: incomplete inactivation triggers seizures, myotonias, arrhythmias, and pain syndromes.

Fouda, Mohamed A; Ghovanloo, Mohammad-Reza; Ruben, Peter C.

J Physiol ; 600(12): 2835-2851, 2022 06.

Artigo em Inglês | MEDLINE | ID: mdl-35436004

4.

Inhibitory effects of cannabidiol on voltage-dependent sodium currents.

Ghovanloo, Mohammad-Reza; Shuart, Noah Gregory; Mezeyova, Janette; Dean, Richard A; Ruben, Peter C; Goodchild, Samuel J.

J Biol Chem ; 293(43): 16546-16558, 2018 10 26.

Artigo em Inglês | MEDLINE | ID: mdl-30219789

5.

pH Modulation of Voltage-Gated Sodium Channels.

Peters, Colin H; Ghovanloo, Mohammad-Reza; Gershome, Cynthia; Ruben, Peter C.

Handb Exp Pharmacol ; 246: 147-160, 2018.

Artigo em Inglês | MEDLINE | ID: mdl-29460150

6.

Functionally-selective inhibition of threshold sodium currents and excitability in dorsal root ganglion neurons by cannabinol.

Ghovanloo, Mohammad-Reza; Effraim, Philip R; Tyagi, Sidharth; Zhao, Peng; Dib-Hajj, Sulayman D; Waxman, Stephen G.

Commun Biol ; 7(1): 120, 2024 01 23.

Artigo em Inglês | MEDLINE | ID: mdl-38263462

7.

Sodium currents in naïve mouse dorsal root ganglion neurons: No major differences between sexes.

Ghovanloo, Mohammad-Reza; Tyagi, Sidharth; Zhao, Peng; Effraim, Philip R; Dib-Hajj, Sulayman D; Waxman, Stephen G.

Channels (Austin) ; 18(1): 2289256, 2024 12.

Artigo em Inglês | MEDLINE | ID: mdl-38055732

8.

Compartment-specific regulation of Na_V1.7 in sensory neurons after acute exposure to TNF-α.

Tyagi, Sidharth; Higerd-Rusli, Grant P; Ghovanloo, Mohammad-Reza; Dib-Hajj, Fadia; Zhao, Peng; Liu, Shujun; Kim, Dong-Hyun; Shim, Ji Seon; Park, Kang-Sik; Waxman, Stephen G; Choi, Jin-Sung; Dib-Hajj, Sulayman D.

Cell Rep ; 43(2): 113685, 2024 Feb 27.

Artigo em Inglês | MEDLINE | ID: mdl-38261513

9.

Molecular Pharmacology of Selective Na_V1.6 and Dual Na_V1.6/Na_V1.2 Channel Inhibitors that Suppress Excitatory Neuronal Activity Ex Vivo.

Goodchild, Samuel J; Shuart, Noah Gregory; Williams, Aaron D; Ye, Wenlei; Parrish, R Ryley; Soriano, Maegan; Thouta, Samrat; Mezeyova, Janette; Waldbrook, Matthew; Dean, Richard; Focken, Thilo; Ghovanloo, Mohammad-Reza; Ruben, Peter C; Scott, Fiona; Cohen, Charles J; Empfield, James; Johnson, J P.

ACS Chem Neurosci ; 15(6): 1169-1184, 2024 Mar 20.

Artigo em Inglês | MEDLINE | ID: mdl-38359277

10.

High-throughput combined voltage-clamp/current-clamp analysis of freshly isolated neurons.

Ghovanloo, Mohammad-Reza; Tyagi, Sidharth; Zhao, Peng; Kiziltug, Emre; Estacion, Mark; Dib-Hajj, Sulayman D; Waxman, Stephen G.

Cell Rep Methods ; 3(1): 100385, 2023 01 23.

Artigo em Inglês | MEDLINE | ID: mdl-36814833

11.

Cannabidiol and Sodium Channel Pharmacology: General Overview, Mechanism, and Clinical Implications.

Ghovanloo, Mohammad-Reza; Ruben, Peter C.

Neuroscientist ; 28(4): 318-334, 2022 08.

Artigo em Inglês | MEDLINE | ID: mdl-34027742

12.

Cannabidiol increases gramicidin current in human embryonic kidney cells: An observational study.

Ghovanloo, Mohammad-Reza; Goodchild, Samuel J; Ruben, Peter C.

PLoS One ; 17(8): e0271801, 2022.

Artigo em Inglês | MEDLINE | ID: mdl-35913948

13.

Non-psychotropic phytocannabinoid interactions with voltage-gated sodium channels: An update on cannabidiol and cannabigerol.

Ghovanloo, Mohammad-Reza; Dib-Hajj, Sulayman D; Goodchild, Samuel J; Ruben, Peter C; Waxman, Stephen G.

Front Physiol ; 13: 1066455, 2022.

Artigo em Inglês | MEDLINE | ID: mdl-36439273

14.

Inhibition of sodium conductance by cannabigerol contributes to a reduction of dorsal root ganglion neuron excitability.

Ghovanloo, Mohammad-Reza; Estacion, Mark; Higerd-Rusli, Grant P; Zhao, Peng; Dib-Hajj, Sulayman; Waxman, Stephen G.

Br J Pharmacol ; 179(15): 4010-4030, 2022 08.

Artigo em Inglês | MEDLINE | ID: mdl-35297036

15.

Cannabidiol inhibits the skeletal muscle Nav1.4 by blocking its pore and by altering membrane elasticity.

Ghovanloo, Mohammad-Reza; Choudhury, Koushik; Bandaru, Tagore S; Fouda, Mohamed A; Rayani, Kaveh; Rusinova, Radda; Phaterpekar, Tejas; Nelkenbrecher, Karen; Watkins, Abeline R; Poburko, Damon; Thewalt, Jenifer; Andersen, Olaf S; Delemotte, Lucie; Goodchild, Samuel J; Ruben, Peter C.

J Gen Physiol ; 153(5)2021 05 03.

Artigo em Inglês | MEDLINE | ID: mdl-33836525

16.

Cannabidiol protects against high glucose-induced oxidative stress and cytotoxicity in cardiac voltage-gated sodium channels.

Fouda, Mohamed A; Ghovanloo, Mohammad-Reza; Ruben, Peter C.

Br J Pharmacol ; 177(13): 2932-2946, 2020 07.

Artigo em Inglês | MEDLINE | ID: mdl-32077098

17.

Biophysical Characterization of a Novel SCN5A Mutation Associated With an Atypical Phenotype of Atrial and Ventricular Arrhythmias and Sudden Death.

Ghovanloo, Mohammad-Reza; Atallah, Joseph; Escudero, Carolina A; Ruben, Peter C.

Front Physiol ; 11: 610436, 2020.

Artigo em Inglês | MEDLINE | ID: mdl-33414724

18.

Cannabidiol interactions with voltage-gated sodium channels.

Sait, Lily Goodyer; Sula, Altin; Ghovanloo, Mohammad-Reza; Hollingworth, David; Ruben, Peter C; Wallace, B A.

Elife ; 92020 10 22.

Artigo em Inglês | MEDLINE | ID: mdl-33089780

19.

Editorial: Cannabinoid interactions with ion channels, receptors, and the bio-membrane.

Ghovanloo, Mohammad-Reza; Arnold, Jonathon C; Ruben, Peter C.

Front Physiol ; 14: 1211230, 2023.

Artigo em Inglês | MEDLINE | ID: mdl-37228821

20.

Effects of acidosis on neuronal voltage-gated sodium channels: Nav1.1 and Nav1.3.

Ghovanloo, Mohammad-Reza; Peters, Colin H; Ruben, Peter C.

Channels (Austin) ; 12(1): 367-377, 2018.

Artigo em Inglês | MEDLINE | ID: mdl-30362397

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