Detalhe da pesquisa
1.
Structure-Based Identification of Naphthoquinones and Derivatives as Novel Inhibitors of Main Protease Mpro and Papain-like Protease PLpro of SARS-CoV-2.
J Chem Inf Model
; 62(24): 6553-6573, 2022 12 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-35960688
2.
Enantioselective inhibition of the SARS-CoV-2 main protease with rhenium(i) picolinic acid complexes.
Chem Sci
; 14(3): 711-720, 2023 Jan 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-36741526
3.
Discovery of pyrazolopyrrolidinones as potent, broad-spectrum inhibitors of Leishmania infection.
Front Trop Dis
; 32023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36818551
4.
Structure-based discovery of thiosemicarbazones as SARS-CoV-2 main protease inhibitors.
Future Med Chem
; 15(11): 959-985, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37435731
5.
Discovery of Triple Inhibitors of Both SARS-CoV-2 Proteases and Human Cathepsin L.
Pharmaceuticals (Basel)
; 15(6)2022 Jun 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-35745663
6.
A Broad Spectrum Antiparasitic Activity of Organotin (IV) Derivatives and Its Untargeted Proteomic Profiling Using Leishmania donovani.
Pathogens
; 11(12)2022 Nov 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-36558759
7.
Structure-based identification of naphthoquinones and derivatives as novel inhibitors of main protease Mpro and papain-like protease PLpro of SARS-CoV-2.
bioRxiv
; 2022 Jan 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35018373
8.
A Clinical-Stage Cysteine Protease Inhibitor blocks SARS-CoV-2 Infection of Human and Monkey Cells.
ACS Chem Biol
; 16(4): 642-650, 2021 04 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-33787221
9.
Novel structural CYP51 mutation in Trypanosoma cruzi associated with multidrug resistance to CYP51 inhibitors and reduced infectivity.
Int J Parasitol Drugs Drug Resist
; 13: 107-120, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32688218
10.
A cysteine protease inhibitor blocks SARS-CoV-2 infection of human and monkey cells.
bioRxiv
; 2020 Oct 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-33140046
11.
Telomere biology of trypanosomatids: beginning to answer some questions.
Trends Parasitol
; 23(8): 357-62, 2007 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-17580124
12.
Nitroheterocyclic compounds are more efficacious than CYP51 inhibitors against Trypanosoma cruzi: implications for Chagas disease drug discovery and development.
Sci Rep
; 4: 4703, 2014 Apr 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-24736467
13.
Visual genome-wide RNAi screening to identify human host factors required for Trypanosoma cruzi infection.
PLoS One
; 6(5): e19733, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-21625474
14.
The putative telomerase reverse transcriptase component of Leishmania amazonensis: gene cloning and characterization.
Parasitol Res
; 98(5): 447-54, 2006 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-16416120