Detalhe da pesquisa
1.
Structural convergence for tubulin binding of CPAP and vinca domain microtubule inhibitors.
Proc Natl Acad Sci U S A
; 119(19): e2120098119, 2022 05 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35507869
2.
Engineering of brick and staple components for ordered assembly of synthetic repeat proteins.
J Struct Biol
; 215(3): 108012, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37567372
3.
The C-terminus of stathmin-like proteins governs the stability of their complexes with tubulin.
Biochem Biophys Res Commun
; 682: 244-249, 2023 11 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-37826947
4.
Insight into microtubule nucleation from tubulin-capping proteins.
Proc Natl Acad Sci U S A
; 116(20): 9859-9864, 2019 05 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-31036638
5.
Elucidating Tau function and dysfunction in the era of cryo-EM.
J Biol Chem
; 294(24): 9316-9325, 2019 06 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-31088912
6.
New Insights into the Coupling between Microtubule Depolymerization and ATP Hydrolysis by Kinesin-13 Protein Kif2C.
J Biol Chem
; 290(30): 18721-31, 2015 Jul 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-26055718
7.
Biochemical and structural insights into microtubule perturbation by CopN from Chlamydia pneumoniae.
J Biol Chem
; 289(36): 25199-210, 2014 Sep 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-25056950
8.
A designed ankyrin repeat protein selected to bind to tubulin caps the microtubule plus end.
Proc Natl Acad Sci U S A
; 109(30): 12011-6, 2012 Jul 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-22778434
9.
Mechanism of Tau-promoted microtubule assembly as probed by NMR spectroscopy.
J Am Chem Soc
; 136(36): 12615-23, 2014 Sep 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-25162583
10.
Kif2C minimal functional domain has unusual nucleotide binding properties that are adapted to microtubule depolymerization.
J Biol Chem
; 287(18): 15143-53, 2012 Apr 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-22403406
11.
Design and characterization of modular scaffolds for tubulin assembly.
J Biol Chem
; 287(37): 31085-94, 2012 Sep 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-22791712
12.
Systematic identification of tubulin-interacting fragments of the microtubule-associated protein Tau leads to a highly efficient promoter of microtubule assembly.
J Biol Chem
; 286(38): 33358-68, 2011 Sep 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-21757739
13.
Structural plasticity of tubulin assembly probed by vinca-domain ligands.
Acta Crystallogr D Biol Crystallogr
; 68(Pt 8): 927-34, 2012 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-22868758
14.
Variations in the colchicine-binding domain provide insight into the structural switch of tubulin.
Proc Natl Acad Sci U S A
; 106(33): 13775-9, 2009 Aug 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-19666559
15.
B-nor-methylene Colchicinoid PT-100 Selectively Induces Apoptosis in Multidrug-Resistant Human Cancer Cells via an Intrinsic Pathway in a Caspase-Independent Manner.
ACS Omega
; 7(3): 2591-2603, 2022 Jan 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-35097257
16.
Structural basis for the regulation of tubulin by vinblastine.
Nature
; 435(7041): 519-22, 2005 May 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-15917812
17.
Structural snapshots of the kinesin-2 OSM-3 along its nucleotide cycle: implications for the ATP hydrolysis mechanism.
FEBS Open Bio
; 11(3): 564-577, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33513284
18.
GTP-dependent formation of straight tubulin oligomers leads to microtubule nucleation.
J Cell Biol
; 220(4)2021 04 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33544140
19.
Structural insight into the inhibition of tubulin by vinca domain peptide ligands.
EMBO Rep
; 9(11): 1101-6, 2008 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-18787557
20.
Insight into tubulin regulation from a complex with colchicine and a stathmin-like domain.
Nature
; 428(6979): 198-202, 2004 Mar 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-15014504