Detalhe da pesquisa
1.
A 19F-qNMR-Guided Mathematical Model for G Protein-Coupled Receptor Signaling.
Mol Pharmacol
; 105(1): 54-62, 2023 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37907352
2.
Insights into adenosine A2A receptor activation through cooperative modulation of agonist and allosteric lipid interactions.
PLoS Comput Biol
; 16(4): e1007818, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32298258
3.
Structural Assessment of Agonist Efficacy in the µ-Opioid Receptor: Morphine and Fentanyl Elicit Different Activation Patterns.
J Chem Inf Model
; 61(3): 1251-1274, 2021 03 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-33448226
4.
Evaluation of Operational Models of Agonism and Allosterism at Receptors with Multiple Orthosteric Binding Sites.
Mol Pharmacol
; 97(1): 35-45, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31704718
5.
Dynamical Correlations Reveal Allosteric Sites in G Protein-Coupled Receptors.
Int J Mol Sci
; 22(1)2020 Dec 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-33375427
6.
Distinct Dopamine D2 Receptor Antagonists Differentially Impact D2 Receptor Oligomerization.
Int J Mol Sci
; 20(7)2019 Apr 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30987329
7.
Representation Learning for Class C G Protein-Coupled Receptors Classification.
Molecules
; 23(3)2018 Mar 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-29562690
8.
Paternal Age and Numerical Chromosome Abnormalities in Human Spermatozoa.
Cytogenet Genome Res
; 148(4): 241-8, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27322585
9.
An allosteric modulator to control endogenous G protein-coupled receptors with light.
Nat Chem Biol
; 10(10): 813-5, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25173999
10.
Overlapping binding sites drive allosteric agonism and positive cooperativity in type 4 metabotropic glutamate receptors.
FASEB J
; 29(1): 116-30, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25342125
11.
Quantifying conformational changes in GPCRs: glimpse of a common functional mechanism.
BMC Bioinformatics
; 16: 124, 2015 Apr 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-25902715
12.
Label noise in subtype discrimination of class C G protein-coupled receptors: A systematic approach to the analysis of classification errors.
BMC Bioinformatics
; 16: 314, 2015 Sep 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-26415951
13.
Helix 3 acts as a conformational hinge in Class A GPCR activation: An analysis of interhelical interaction energies in crystal structures.
J Struct Biol
; 192(3): 545-553, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26522273
14.
Computational analysis of negative and positive allosteric modulator binding and function in metabotropic glutamate receptor 5 (in)activation.
J Chem Inf Model
; 54(5): 1476-87, 2014 May 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-24793143
15.
Mathematical modeling of G protein-coupled receptor function: what can we learn from empirical and mechanistic models?
Adv Exp Med Biol
; 796: 159-81, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24158805
16.
Time-dependent ligand-receptor binding kinetics and functionality in a heterodimeric receptor model.
Biochem Pharmacol
; 225: 116299, 2024 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-38763260
17.
ERNEST COST action overview on the (patho)physiology of GPCRs and orphan GPCRs in the nervous system.
Br J Pharmacol
; 2024 Jun 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38825750
18.
Allosteric binding cooperativity in a kinetic context.
Drug Discov Today
; 28(2): 103441, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36372329
19.
Factors associated with the intensity of anxiety and depression symptoms in health workers of two centres of reference for COVID 19 patient care in Antioquia, Colombia - A latent class analysis.
Rev Colomb Psiquiatr (Engl Ed)
; 52(4): 352-361, 2023.
Artigo
em Inglês, Espanhol
| MEDLINE | ID: mdl-38008668
20.
Remote local photoactivation of morphine produces analgesia without opioid-related adverse effects.
Br J Pharmacol
; 180(7): 958-974, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34363210