Detalhe da pesquisa
1.
Transcriptional programs that control expression of the autoimmune regulator gene Aire.
Nat Immunol
; 18(2): 161-172, 2017 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27941786
2.
The deacetylase Sirt1 is an essential regulator of Aire-mediated induction of central immunological tolerance.
Nat Immunol
; 16(7): 737-45, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-26006015
3.
Aire's partners in the molecular control of immunological tolerance.
Cell
; 140(1): 123-35, 2010 Jan 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-20085707
4.
Aire-dependent transcripts escape Raver2-induced splice-event inclusion in the thymic epithelium.
EMBO Rep
; 23(3): e53576, 2022 02 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35037357
5.
Non-permissive human conventional CD1c+ dendritic cells enable trans-infection of human primary renal tubular epithelial cells and protect BK polyomavirus from neutralization.
PLoS Pathog
; 17(2): e1009042, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33592065
6.
Recirculating Foxp3+ regulatory T cells are restimulated in the thymus under Aire control.
Cell Mol Life Sci
; 79(7): 355, 2022 Jun 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35678896
7.
An RNAi screen for Aire cofactors reveals a role for Hnrnpl in polymerase release and Aire-activated ectopic transcription.
Proc Natl Acad Sci U S A
; 111(4): 1491-6, 2014 Jan 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-24434558
8.
Aire unleashes stalled RNA polymerase to induce ectopic gene expression in thymic epithelial cells.
Proc Natl Acad Sci U S A
; 109(2): 535-40, 2012 Jan 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-22203960
9.
New biphasic solvent system based on cyclopentyl methyl ether for the purification of a non-polar synthetic peptide by pH-zone refining centrifugal partition chromatography.
J Sep Sci
; 37(11): 1222-8, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24668688
10.
Brief report: candidate gene study in systemic sclerosis identifies a rare and functional variant of the TNFAIP3 locus as a risk factor for polyautoimmunity.
Arthritis Rheum
; 64(8): 2746-52, 2012 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-22488580
11.
An IRF8-binding promoter variant and AIRE control CHRNA1 promiscuous expression in thymus.
Nature
; 448(7156): 934-7, 2007 Aug 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-17687331
12.
Differentiation of Pluripotent Stem Cells Into Thymic Epithelial Cells and Generation of Thymic Organoids: Applications for Therapeutic Strategies Against APECED.
Front Immunol
; 13: 930963, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35844523
13.
Thymocytes trigger self-antigen-controlling pathways in immature medullary thymic epithelial stages.
Elife
; 112022 02 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-35188458
14.
AIRE deficiency, from preclinical models to human APECED disease.
Dis Model Mech
; 14(2)2021 02 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33729987
15.
CD8+ T Cells Variably Recognize Native Versus Citrullinated GRP78 Epitopes in Type 1 Diabetes.
Diabetes
; 70(12): 2879-2891, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34561224
16.
Aire-dependent genes undergo Clp1-mediated 3'UTR shortening associated with higher transcript stability in the thymus.
Elife
; 92020 04 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-32338592
17.
1,2-Dimethylindole-3-sulfonyl (MIS) as protecting group for the side chain of arginine.
Org Biomol Chem
; 7(12): 2565-9, 2009 Jun 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-19503931
18.
Human Tolerogenic Dendritic Cells Regulate Immune Responses through Lactate Synthesis.
Cell Metab
; 30(6): 1075-1090.e8, 2019 12 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31801055
19.
Genetic factors in autoimmune myasthenia gravis.
Ann N Y Acad Sci
; 1132: 180-92, 2008.
Artigo
em Inglês
| MEDLINE | ID: mdl-18567868
20.
Editorial: Thymic function at single cell resolution.
Front Immunol
; 14: 1358957, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-38259446