Detalhe da pesquisa
1.
Synthesis and biological activity of a series of tetrasubstituted-imidazoles as P2X(7) antagonists.
Bioorg Med Chem Lett
; 20(16): 4951-4, 2010 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20634071
2.
Structure-activity relationships and in vivo activity of (1H-pyrazol-4-yl)acetamide antagonists of the P2X(7) receptor.
Bioorg Med Chem Lett
; 20(15): 4653-6, 2010 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20579878
3.
Synthesis and structure-activity relationships of a series of (1H-pyrazol-4-yl)acetamide antagonists of the P2X7 receptor.
Bioorg Med Chem Lett
; 20(10): 3161-4, 2010 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20399651
4.
Synthesis and evaluation of 3-amino-6-aryl-pyridazines as selective CB(2) agonists for the treatment of inflammatory pain.
Bioorg Med Chem Lett
; 20(2): 465-8, 2010 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20005703
5.
Identification of 2-oxo-N-(phenylmethyl)-4-imidazolidinecarboxamide antagonists of the P2X(7) receptor.
Bioorg Med Chem Lett
; 20(22): 6370-4, 2010 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20934331
6.
Discovery and structure-activity relationships of a series of pyroglutamic acid amide antagonists of the P2X7 receptor.
Bioorg Med Chem Lett
; 20(17): 5080-4, 2010 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20673717
7.
2-Amino-5-aryl-pyridines as selective CB2 agonists: synthesis and investigation of structure-activity relationships.
Bioorg Med Chem Lett
; 19(23): 6578-81, 2009 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19864133
8.
Identification and optimisation of a novel series of pyrimidine based cyclooxygenase-2 (COX-2) inhibitors. Utilisation of a biotransformation approach.
Bioorg Med Chem Lett
; 19(15): 4509-14, 2009 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19523822
9.
Identification of [4-[4-(methylsulfonyl)phenyl]-6-(trifluoromethyl)-2-pyrimidinyl] amines and ethers as potent and selective cyclooxygenase-2 inhibitors.
Bioorg Med Chem Lett
; 19(15): 4504-8, 2009 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19520573
10.
Structure-activity relationships of 1,5-biaryl pyrroles as EP1 receptor antagonists.
Bioorg Med Chem Lett
; 16(14): 3657-62, 2006 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-16697196