Detalhe da pesquisa
1.
Metabolic Fingerprinting Links Oncogenic PIK3CA with Enhanced Arachidonic Acid-Derived Eicosanoids.
Cell
; 181(7): 1596-1611.e27, 2020 06 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-32559461
2.
International Union of Basic and Clinical Pharmacology. CVII. Structure and Pharmacology of the Apelin Receptor with a Recommendation that Elabela/Toddler Is a Second Endogenous Peptide Ligand.
Pharmacol Rev
; 71(4): 467-502, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31492821
3.
Consequences of Lipid Remodeling of Adipocyte Membranes Being Functionally Distinct from Lipid Storage in Obesity.
J Proteome Res
; 19(10): 3919-3935, 2020 10 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32646215
4.
SPUTNIK: an R package for filtering of spatially related peaks in mass spectrometry imaging data.
Bioinformatics
; 35(1): 178-180, 2019 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30010780
5.
The nPYc-Toolbox, a Python module for the pre-processing, quality-control and analysis of metabolic profiling datasets.
Bioinformatics
; 35(24): 5359-5360, 2019 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31350543
6.
Validating the validation: reanalyzing a large-scale comparison of deep learning and machine learning models for bioactivity prediction.
J Comput Aided Mol Des
; 34(7): 717-730, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31960253
7.
Colocalization Features for Classification of Tumors Using Desorption Electrospray Ionization Mass Spectrometry Imaging.
Anal Chem
; 91(10): 6530-6540, 2019 05 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-31013058
8.
Elabela/Toddler Is an Endogenous Agonist of the Apelin APJ Receptor in the Adult Cardiovascular System, and Exogenous Administration of the Peptide Compensates for the Downregulation of Its Expression in Pulmonary Arterial Hypertension.
Circulation
; 135(12): 1160-1173, 2017 Mar 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-28137936
9.
Pharmacological targeting of apelin impairs glioblastoma growth.
Brain
; 140(11): 2939-2954, 2017 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29053791
10.
Analysis of Differential Efficacy and Affinity of GABAA (α1/α2) Selective Modulators.
Mol Pharm
; 13(11): 4001-4012, 2016 11 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27704838
11.
A combination of computational and experimental approaches identifies DNA sequence constraints associated with target site binding specificity of the transcription factor CSL.
Nucleic Acids Res
; 42(16): 10550-63, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25114055
12.
How diverse are diversity assessment methods? A comparative analysis and benchmarking of molecular descriptor space.
J Chem Inf Model
; 54(1): 230-42, 2014 Jan 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-24289493
13.
The biased apelin receptor agonist, MM07, reverses Sugen/hypoxia-induced pulmonary arterial hypertension as effectively as the endothelin antagonist macitentan.
Front Pharmacol
; 15: 1369489, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38655187
14.
Prediction of cytochrome P450 xenobiotic metabolism: tethered docking and reactivity derived from ligand molecular orbital analysis.
J Chem Inf Model
; 53(6): 1294-305, 2013 Jun 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-23701380
15.
Chemogenomics approaches to rationalizing the mode-of-action of traditional Chinese and Ayurvedic medicines.
J Chem Inf Model
; 53(3): 661-73, 2013 Mar 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-23351136
16.
In silico target predictions: defining a benchmarking data set and comparison of performance of the multiclass Naïve Bayes and Parzen-Rosenblatt window.
J Chem Inf Model
; 53(8): 1957-66, 2013 Aug 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-23829430
17.
FAst MEtabolizer (FAME): A rapid and accurate predictor of sites of metabolism in multiple species by endogenous enzymes.
J Chem Inf Model
; 53(11): 2896-907, 2013 Nov 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-24219364
18.
How do metabolites differ from their parent molecules and how are they excreted?
J Chem Inf Model
; 53(2): 354-67, 2013 Feb 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-23351040
19.
Note on naive Bayes based on binary descriptors in cheminformatics.
J Chem Inf Model
; 52(10): 2494-500, 2012 Oct 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-22900941
20.
Computational prediction of metabolism: sites, products, SAR, P450 enzyme dynamics, and mechanisms.
J Chem Inf Model
; 52(3): 617-48, 2012 Mar 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-22339582