Detalhe da pesquisa
1.
Molecular Mechanism of Labelling Functional Cysteines by Heterocyclic Thiones.
Chemphyschem
; 25(1): e202300596, 2024 Jan 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-37888491
2.
Boronic acid inhibitors of penicillin-binding protein 1b: serine and lysine labelling agents.
J Enzyme Inhib Med Chem
; 39(1): 2305833, 2024 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-38410950
3.
Nep1-like proteins as a target for plant pathogen control.
PLoS Pathog
; 17(4): e1009477, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33857257
4.
Mur ligase F as a new target for the flavonoids quercitrin, myricetin, and (-)-epicatechin.
J Comput Aided Mol Des
; 37(12): 721-733, 2023 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37796382
5.
Evaluation of novel cathepsin-X inhibitors in vitro and in vivo and their ability to improve cathepsin-B-directed antitumor therapy.
Cell Mol Life Sci
; 79(1): 34, 2022 Jan 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34989869
6.
Discovery of a fragment hit compound targeting D-Ala:D-Ala ligase of bacterial peptidoglycan biosynthesis.
J Enzyme Inhib Med Chem
; 38(1): 387-397, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-36446617
7.
DNA-encoded library screening on two validated enzymes of the peptidoglycan biosynthetic pathway.
Bioorg Med Chem Lett
; 73: 128915, 2022 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35917835
8.
ProBiS-Dock: A Hybrid Multitemplate Homology Flexible Docking Algorithm Enabled by Protein Binding Site Comparison.
J Chem Inf Model
; 62(6): 1573-1584, 2022 03 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-35289616
9.
Indoles and 1-(3-(benzyloxy)benzyl)piperazines: Reversible and selective monoamine oxidase B inhibitors identified by screening an in-house compound library.
Bioorg Chem
; 119: 105581, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34990933
10.
Design, synthesis and biological evaluation of substituted 3-amino-N-(thiazol-2-yl)pyrazine-2-carboxamides as inhibitors of mycobacterial methionine aminopeptidase 1.
Bioorg Chem
; 118: 105489, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34826708
11.
Upregulation of Cathepsin X in Glioblastoma: Interplay with γ-Enolase and the Effects of Selective Cathepsin X Inhibitors.
Int J Mol Sci
; 23(3)2022 Feb 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35163706
12.
Screening of Big Pharma's Library against Various in-house Biological Targets.
Molecules
; 27(14)2022 Jul 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-35889355
13.
N-Hydroxy-N-Propargylamide Derivatives of Ferulic Acid: Inhibitors of Cholinesterases and Monoamine Oxidases.
Molecules
; 27(21)2022 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36364263
14.
Assessment of Tractable Cysteines for Covalent Targeting by Screening Covalent Fragments.
Chembiochem
; 22(4): 743-753, 2021 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33030752
15.
Mur ligases inhibitors with azastilbene scaffold: Expanding the structure-activity relationship.
Bioorg Med Chem Lett
; 40: 127966, 2021 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33744441
16.
WIDOCK: a reactive docking protocol for virtual screening of covalent inhibitors.
J Comput Aided Mol Des
; 35(2): 223-244, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33458809
17.
Synthesis of 3-Amino-4-substituted Monocyclic ß-Lactams-Important Structural Motifs in Medicinal Chemistry.
Int J Mol Sci
; 23(1)2021 Dec 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-35008788
18.
4-Phenethyl-1-Propargylpiperidine-Derived Dual Inhibitors of Butyrylcholinesterase and Monoamine Oxidase B.
Molecules
; 26(14)2021 Jul 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34299393
19.
Synthesis and Biochemical Evaluation of Warhead-Decorated Psoralens as (Immuno)Proteasome Inhibitors.
Molecules
; 26(2)2021 Jan 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33445542
20.
Development of potent reversible selective inhibitors of butyrylcholinesterase as fluorescent probes.
J Enzyme Inhib Med Chem
; 35(1): 498-505, 2020 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-31914836