Detalhe da pesquisa
1.
Isothiazolidinone inhibitors of PTP1B containing imidazoles and imidazolines.
Bioorg Med Chem Lett
; 18(1): 66-71, 2008 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18037290
2.
Potent benzimidazole sulfonamide protein tyrosine phosphatase 1B inhibitors containing the heterocyclic (S)-isothiazolidinone phosphotyrosine mimetic.
J Med Chem
; 49(13): 3774-89, 2006 Jun 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-16789735
3.
Structure-based design and discovery of protein tyrosine phosphatase inhibitors incorporating novel isothiazolidinone heterocyclic phosphotyrosine mimetics.
J Med Chem
; 48(21): 6544-8, 2005 Oct 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-16220970
4.
Benzothiazole benzimidazole (S)-isothiazolidinone derivatives as protein tyrosine phosphatase-1B inhibitors.
Bioorg Med Chem Lett
; 17(3): 736-40, 2007 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17097290
5.
Isothiazolidinone heterocycles as inhibitors of protein tyrosine phosphatases: synthesis and structure-activity relationships of a peptide scaffold.
Bioorg Med Chem
; 14(17): 5833-49, 2006 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16769216
6.
Structural basis for inhibition of protein-tyrosine phosphatase 1B by isothiazolidinone heterocyclic phosphonate mimetics.
J Biol Chem
; 281(43): 32784-95, 2006 Oct 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-16916797
7.
Structural insights into the design of nonpeptidic isothiazolidinone-containing inhibitors of protein-tyrosine phosphatase 1B.
J Biol Chem
; 281(49): 38013-21, 2006 Dec 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-17028182