Detalhe da pesquisa
1.
Sphingosine 1-phosphate receptor signaling.
Annu Rev Biochem
; 78: 743-68, 2009.
Artigo
em Inglês
| MEDLINE | ID: mdl-19231986
2.
Bitopic Sphingosine 1-Phosphate Receptor 3 (S1P3) Antagonist Rescue from Complete Heart Block: Pharmacological and Genetic Evidence for Direct S1P3 Regulation of Mouse Cardiac Conduction.
Mol Pharmacol
; 89(1): 176-86, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26494861
3.
The organization of the sphingosine 1-phosphate signaling system.
Curr Top Microbiol Immunol
; 378: 1-21, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24728591
4.
Sphingosine 1-phosphate receptor 1 (S1P(1)) upregulation and amelioration of experimental autoimmune encephalomyelitis by an S1P(1) antagonist.
Mol Pharmacol
; 83(2): 316-21, 2013 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-23204443
5.
Actions of a picomolar short-acting S1P1 agonist in S1P1-eGFP knock-in mice.
Nat Chem Biol
; 7(5): 254-6, 2011 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-21445057
6.
Real-time differential labeling of blood, interstitium, and lymphatic and single-field analysis of vasculature dynamics in vivo.
Am J Physiol Cell Physiol
; 302(10): C1460-8, 2012 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22357735
7.
S1P(1) receptor modulation with cyclical recovery from lymphopenia ameliorates mouse model of multiple sclerosis.
Mol Pharmacol
; 81(2): 166-74, 2012 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-22031473
8.
Full pharmacological efficacy of a novel S1P1 agonist that does not require S1P-like headgroup interactions.
Mol Pharmacol
; 74(5): 1308-18, 2008 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-18708635
9.
S1P1-selective in vivo-active agonists from high-throughput screening: off-the-shelf chemical probes of receptor interactions, signaling, and fate.
Chem Biol
; 12(6): 703-15, 2005 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-15975516
10.
The alpha(1B)-adrenergic receptor decreases the inotropic response in the mouse Langendorff heart model.
Cardiovasc Res
; 60(3): 598-607, 2003 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-14659805
11.
Differential regulation of the cell cycle by alpha1-adrenergic receptor subtypes.
Endocrinology
; 145(11): 5157-67, 2004 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-15297446
12.
S1P signaling: new therapies and opportunities.
F1000Prime Rep
; 6: 109, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25580263
13.
Ligand-binding pocket shape differences between sphingosine 1-phosphate (S1P) receptors S1P1 and S1P3 determine efficiency of chemical probe identification by ultrahigh-throughput screening.
ACS Chem Biol
; 3(8): 486-98, 2008 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18590333
14.
Mapping pathways downstream of sphingosine 1-phosphate subtype 1 by differential chemical perturbation and proteomics.
J Biol Chem
; 282(10): 7254-64, 2007 Mar 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-17218309
15.
Tipping the gatekeeper: S1P regulation of endothelial barrier function.
Trends Immunol
; 28(3): 102-7, 2007 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-17276731
16.
Enhancement of capillary leakage and restoration of lymphocyte egress by a chiral S1P1 antagonist in vivo.
Nat Chem Biol
; 2(8): 434-41, 2006 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-16829954
17.
Relationship between alpha(1)-adrenergic receptor-induced contraction and extracellular signal-regulated kinase activation in the bovine inferior alveolar artery.
J Pharmacol Exp Ther
; 303(1): 403-11, 2002 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-12235277
18.
Tonic inhibitory role for cAMP in alpha(1a)-adrenergic receptor coupling to extracellular signal-regulated kinases 1/2.
J Pharmacol Exp Ther
; 303(1): 247-56, 2002 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-12235258
19.
Genetic profiling of alpha 1-adrenergic receptor subtypes by oligonucleotide microarrays: coupling to interleukin-6 secretion but differences in STAT3 phosphorylation and gp-130.
Mol Pharmacol
; 63(5): 1104-16, 2003 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-12695539
20.
Gene expression profile of neurodegeneration induced by alpha1B-adrenergic receptor overactivity: NMDA/GABAA dysregulation and apoptosis.
Brain
; 126(Pt 12): 2667-81, 2003 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-12937073