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2.
Clin Transl Oncol ; 23(3): 434-449, 2021 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-32623581

RESUMO

The implementation of immunotherapy has radically changed the treatment of oncological patients. Currently, immunotherapy is indicated in the treatment of patients with head and neck tumors, melanoma, lung cancer, bladder tumors, colon cancer, cervical cancer, breast cancer, Merkel cell carcinoma, liver cancer, leukemia and lymphomas. However, its efficacy is restricted to a limited number of cases. The challenge is, therefore, to identify which subset of patients would benefit from immunotherapy. To this end, the establishment of immunotherapy response criteria and predictive and prognostic biomarkers is of paramount interest. In this report, a group of experts of the Spanish Society of Medical Oncology (SEOM), the Spanish Society of Medical Radiology (SERAM), and Spanish Society of Nuclear Medicine and Molecular Imaging (SEMNIM) provide an up-to-date review and a consensus guide on these issues.


Assuntos
Consenso , Imunoterapia/métodos , Neoplasias/terapia , Sociedades Médicas , Progressão da Doença , Humanos , Inibidores de Checkpoint Imunológico/uso terapêutico , Imunoterapia/efeitos adversos , Oncologia , Neoplasias/diagnóstico por imagem , Neoplasias/imunologia , Medicina Nuclear , Radiologia , Critérios de Avaliação de Resposta em Tumores Sólidos , Espanha , Resultado do Tratamento
7.
Arch Soc Esp Oftalmol ; 78(4): 227-30, 2003 Apr.
Artigo em Espanhol | MEDLINE | ID: mdl-12743849

RESUMO

CASE REPORT: We report the case of a 44-year-old woman, with a history of cigarette smoking (60 per day) and hyperthyroidism. She presented a bilateral ocular ischemic syndrome, and a bilateral occlusive carotid artery disease which showed reverse ophthalmic artery flow that resulted in a steal phenomenon, characterized by a shunt to the low resistance intracranial circuits and reduction of blood flow to the eyes. DISCUSSION: Young patients with severe bilateral occlusive carotid artery disease may be at greater risk of developing ocular ischemic syndrome, while this reverse flow decreases the patient's risk of stroke and death.


Assuntos
Artéria Carótida Interna/fisiopatologia , Estenose das Carótidas/fisiopatologia , Circulação Colateral , Isquemia/fisiopatologia , Artéria Oftálmica/fisiopatologia , Adulto , Velocidade do Fluxo Sanguíneo , Artéria Carótida Interna/diagnóstico por imagem , Estenose das Carótidas/diagnóstico por imagem , Feminino , Hemodinâmica , Humanos , Radiografia , Artéria Retiniana/fisiopatologia , Fumar/efeitos adversos , Acuidade Visual
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