Detalhe da pesquisa
1.
Mechanisms that promote and suppress chromosomal translocations in lymphocytes.
Annu Rev Immunol
; 29: 319-50, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-21219174
2.
Genome-wide translocation sequencing reveals mechanisms of chromosome breaks and rearrangements in B cells.
Cell
; 147(1): 107-19, 2011 Sep 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-21962511
3.
Phosphatidylinositol 3-kinase δ blockade increases genomic instability in B cells.
Nature
; 542(7642): 489-493, 2017 02 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-28199309
4.
Orientation-specific joining of AID-initiated DNA breaks promotes antibody class switching.
Nature
; 525(7567): 134-139, 2015 Sep 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-26308889
5.
Aberrant TCRδ rearrangement underlies the T-cell lymphocytopenia and t(12;14) translocation associated with ATM deficiency.
Blood
; 125(17): 2665-8, 2015 Apr 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-25721125
6.
Developmental propagation of V(D)J recombination-associated DNA breaks and translocations in mature B cells via dicentric chromosomes.
Proc Natl Acad Sci U S A
; 111(28): 10269-74, 2014 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24982162
7.
IgH class switching exploits a general property of two DNA breaks to be joined in cis over long chromosomal distances.
Proc Natl Acad Sci U S A
; 111(7): 2644-9, 2014 Feb 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-24550291
8.
Conditional inactivation of p53 in mature B cells promotes generation of nongerminal center-derived B-cell lymphomas.
Proc Natl Acad Sci U S A
; 110(8): 2934-9, 2013 Feb 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-23382223
9.
Long-range oncogenic activation of Igh-c-myc translocations by the Igh 3' regulatory region.
Nature
; 462(7274): 803-7, 2009 Dec 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-20010689
10.
Mechanisms promoting translocations in editing and switching peripheral B cells.
Nature
; 460(7252): 231-6, 2009 Jul 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-19587764
11.
Robust chromosomal DNA repair via alternative end-joining in the absence of X-ray repair cross-complementing protein 1 (XRCC1).
Proc Natl Acad Sci U S A
; 109(7): 2473-8, 2012 Feb 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-22308491
12.
Inhibition of LILRB2 by a Novel Blocking Antibody Designed to Reprogram Immunosuppressive Macrophages to Drive T-Cell Activation in Tumors.
Mol Cancer Ther
; 22(4): 471-484, 2023 04 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36780212
13.
Chromosomal location targets different MYC family gene members for oncogenic translocations.
Proc Natl Acad Sci U S A
; 106(7): 2265-70, 2009 Feb 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-19174520
14.
ICOS is upregulated on T cells following radiation and agonism combined with radiation results in enhanced tumor control.
Sci Rep
; 12(1): 14954, 2022 Sep 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36056093
15.
Differential expression of CCR8 in tumors versus normal tissue allows specific depletion of tumor-infiltrating T regulatory cells by GS-1811, a novel Fc-optimized anti-CCR8 antibody.
Oncoimmunology
; 11(1): 2141007, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36352891
16.
Excision of reprogramming transgenes improves the differentiation potential of iPS cells generated with a single excisable vector.
Stem Cells
; 28(1): 64-74, 2010 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-19904830
17.
Regulation of p53 functions: let's meet at the nuclear bodies.
Curr Opin Cell Biol
; 15(3): 351-7, 2003 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-12787779
18.
Homeodomain-interacting protein kinase-2 phosphorylates p53 at Ser 46 and mediates apoptosis.
Nat Cell Biol
; 4(1): 11-9, 2002 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-11780126
19.
ICOS agonism by JTX-2011 (vopratelimab) requires initial T cell priming and Fc cross-linking for optimal T cell activation and anti-tumor immunity in preclinical models.
PLoS One
; 15(9): e0239595, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32970735
20.
Direct p53 transcriptional repression: in vivo analysis of CCAAT-containing G2/M promoters.
Mol Cell Biol
; 25(9): 3737-51, 2005 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-15831478