Detalhe da pesquisa
1.
Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages.
Cell
; 167(2): 457-470.e13, 2016 Oct 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27667687
2.
Regulation of nucleo-cytosolic 26S proteasome translocation by aromatic amino acids via mTOR is essential for cell survival under stress.
Mol Cell
; 83(18): 3333-3346.e5, 2023 09 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-37738964
3.
Predicting cancer-specific vulnerability via data-driven detection of synthetic lethality.
Cell
; 158(5): 1199-1209, 2014 Aug 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-25171417
4.
Failure to mate enhances investment in behaviors that may promote mating reward and impairs the ability to cope with stressors via a subpopulation of Neuropeptide F receptor neurons.
PLoS Genet
; 20(1): e1011054, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-38236837
5.
Metabolic adaptation to consume butyrate under prolonged resource exhaustion.
PLoS Genet
; 19(6): e1010812, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37347785
6.
Impairment of serine transport across the blood-brain barrier by deletion of Slc38a5 causes developmental delay and motor dysfunction.
Proc Natl Acad Sci U S A
; 120(42): e2302780120, 2023 10 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-37812701
7.
Host autophagy mediates organ wasting and nutrient mobilization for tumor growth.
EMBO J
; 40(18): e107336, 2021 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34309071
8.
KRAS4A directly regulates hexokinase 1.
Nature
; 576(7787): 482-486, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31827279
9.
Hyperglucagonaemia in diabetes: altered amino acid metabolism triggers mTORC1 activation, which drives glucagon production.
Diabetologia
; 66(10): 1925-1942, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37480416
10.
Cellular and metabolic characteristics of pre-leukemic hematopoietic progenitors with GATA2 haploinsufficiency.
Haematologica
; 108(9): 2316-2330, 2023 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36475518
11.
Fumarate is an epigenetic modifier that elicits epithelial-to-mesenchymal transition.
Nature
; 537(7621): 544-547, 2016 08 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-27580029
12.
Bioenergetic and Metabolic Impairments in Induced Pluripotent Stem Cell-Derived Cardiomyocytes Generated from Duchenne Muscular Dystrophy Patients.
Int J Mol Sci
; 23(17)2022 Aug 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-36077200
13.
Depressed ß-adrenergic inotropic responsiveness and intracellular calcium handling abnormalities in Duchenne Muscular Dystrophy patients' induced pluripotent stem cell-derived cardiomyocytes.
J Cell Mol Med
; 25(8): 3922-3934, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33619882
14.
Extracellular adenosine sensing-a metabolic cell death priming mechanism downstream of p53.
Mol Cell
; 50(3): 394-406, 2013 May 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-23603120
15.
Investigating LMNA-Related Dilated Cardiomyopathy Using Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes.
Int J Mol Sci
; 22(15)2021 Jul 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-34360639
16.
MYC regulates fatty acid metabolism through a multigenic program in claudin-low triple negative breast cancer.
Br J Cancer
; 122(6): 868-884, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31942031
17.
Glutaminolysis activates Rag-mTORC1 signaling.
Mol Cell
; 47(3): 349-58, 2012 Aug 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-22749528
18.
Serine starvation induces stress and p53-dependent metabolic remodelling in cancer cells.
Nature
; 493(7433): 542-6, 2013 Jan 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-23242140
19.
p53 status determines the role of autophagy in pancreatic tumour development.
Nature
; 504(7479): 296-300, 2013 Dec 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-24305049
20.
A key role for mitochondrial gatekeeper pyruvate dehydrogenase in oncogene-induced senescence.
Nature
; 498(7452): 109-12, 2013 Jun 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-23685455