Detalhe da pesquisa
1.
Hepatitis C virus RNA is 5'-capped with flavin adenine dinucleotide.
Nature
; 619(7971): 811-818, 2023 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-37407817
2.
JFH1-based Core-NS2 genotype variants of HCV with genetic stability in vivo and in vitro: Important tools in evaluation of virus neutralization.
Hepatology
; 2024 Apr 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-38652584
3.
Characterization of multi-DAA resistance using a novel hepatitis C virus genotype 3a infectious culture system.
Hepatology
; 78(2): 621-636, 2023 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36999539
4.
Identification of novel neutralizing determinants for protection against HCV.
Hepatology
; 77(3): 982-996, 2023 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36056620
5.
Inactivated genotype 1a, 2a and 3a HCV vaccine candidates induced broadly neutralising antibodies in mice.
Gut
; 72(3): 560-572, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35918103
6.
Inactivated whole hepatitis C virus vaccine employing a licensed adjuvant elicits cross-genotype neutralizing antibodies in mice.
J Hepatol
; 76(5): 1051-1061, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34990750
7.
Hepatitis C Virus Protease Inhibitors Show Differential Efficacy and Interactions with Remdesivir for Treatment of SARS-CoV-2 In Vitro.
Antimicrob Agents Chemother
; 65(9): e0268020, 2021 08 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-34097489
8.
Overcoming Culture Restriction for SARS-CoV-2 in Human Cells Facilitates the Screening of Compounds Inhibiting Viral Replication.
Antimicrob Agents Chemother
; 65(7): e0009721, 2021 06 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-33903110
9.
Evolutionary Pathways to Persistence of Highly Fit and Resistant Hepatitis C Virus Protease Inhibitor Escape Variants.
Hepatology
; 70(3): 771-787, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30964552
10.
HCV genotype 1-6 NS3 residue 80 substitutions impact protease inhibitor activity and promote viral escape.
J Hepatol
; 70(3): 388-397, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30395912
11.
HCV Genotype 6a Escape From and Resistance to Velpatasvir, Pibrentasvir, and Sofosbuvir in Robust Infectious Cell Culture Models.
Gastroenterology
; 154(8): 2194-2208.e12, 2018 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29454794
12.
Efficacy of NS5A Inhibitors Against Hepatitis C Virus Genotypes 1-7 and Escape Variants.
Gastroenterology
; 154(5): 1435-1448, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29274866
13.
Efficient Hepatitis C Virus Genotype 1b Core-NS5A Recombinants Permit Efficacy Testing of Protease and NS5A Inhibitors.
Antimicrob Agents Chemother
; 61(6)2017 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28348150
14.
Robust HCV Genotype 3a Infectious Cell Culture System Permits Identification of Escape Variants With Resistance to Sofosbuvir.
Gastroenterology
; 151(5): 973-985.e2, 2016 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27453546
15.
Hepatitis C Virus Genotype 1 to 6 Protease Inhibitor Escape Variants: In Vitro Selection, Fitness, and Resistance Patterns in the Context of the Infectious Viral Life Cycle.
Antimicrob Agents Chemother
; 60(6): 3563-78, 2016 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27021330
16.
Adaptive Mutations Enhance Assembly and Cell-to-Cell Transmission of a High-Titer Hepatitis C Virus Genotype 5a Core-NS2 JFH1-Based Recombinant.
J Virol
; 89(15): 7758-75, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-25995244
17.
Substitutions at NS3 Residue 155, 156, or 168 of Hepatitis C Virus Genotypes 2 to 6 Induce Complex Patterns of Protease Inhibitor Resistance.
Antimicrob Agents Chemother
; 59(12): 7426-36, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26392503
18.
Differential sensitivity of 5'UTR-NS5A recombinants of hepatitis C virus genotypes 1-6 to protease and NS5A inhibitors.
Gastroenterology
; 146(3): 812-821.e4, 2014 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-24262279
19.
Hypervariable region 1 deletion and required adaptive envelope mutations confer decreased dependency on scavenger receptor class B type I and low-density lipoprotein receptor for hepatitis C virus.
J Virol
; 88(3): 1725-39, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24257605
20.
Productive homologous and non-homologous recombination of hepatitis C virus in cell culture.
PLoS Pathog
; 9(3): e1003228, 2013 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-23555245