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1.
Ann Dermatol Venereol ; 148(3): 156-160, 2021 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-33487487

RESUMO

INTRODUCTION: Simulation in healthcare is a rapidly developing teaching method in the training of technical procedures. It is also used to enable caregivers to learn how to inform patients of serious illness and complex health status. However, its use is not widespread in the field of dermatology. This study investigated the utility of simulation as regards disclosing melanoma diagnosis, taking resident physician satisfaction as a primary endpoint. MATERIALS AND METHODS: Fifteen dermatology residents were recruited as trainees. Four scenarios were allocated based on length of residency. An introductory briefing was held prior to the training sessions. Debriefing took place on completion of the diagnosis disclosure consultation. The participants completed questionnaires after the simulation session, after debriefing, and 3 months after the simulation session. The primary endpoint was usefulness of the session felt by trainees several months after the simulation. RESULTS: The majority of participants (93.3%) thought the session helped with stress management, improved their attitude and control over their reaction (86.6%), and improved their communication skills (100%). They rated the usefulness of the simulation at 7.79/10 on average (range: 5-10). DISCUSSION: According to our findings the resident physicians involved, particularly those with the least experience, were satisfied with this type of learning technique. Any difficulties encountered by these residents were brought to light and addressed during debriefing. CONCLUSION: There would appear to be real benefits to be reaped from simulation, whatever the stage of medical training at which it takes place. Simulation should become an increasingly important part of contemporary pregraduate specialty programs.


Assuntos
Dermatologia , Internato e Residência , Competência Clínica , Comunicação , Humanos , Inquéritos e Questionários
2.
Ann Dermatol Venereol ; 147(5): 340-349, 2020 May.
Artigo em Francês | MEDLINE | ID: mdl-32220476

RESUMO

BACKGROUND: C1INH-deficiency hereditary angioedema (HAE) is characterized by recurrent episodes of potentially severe oedema. Icatibant for SC injection will soon be approved for use in children and it is necessary to train parents in recognising severe episodes of AOH and in the technique for injection of icatibant. Simulation in healthcare (SH) is a set of educational methods for improving skills in a safe environment. We wished to assess the feasibility of a therapeutic training session (TTS) involving scripted scenarios for the parents of children with HAE. PATIENTS AND METHODS: The TTS session included pre- and post-training testing on AOH, two scenarios (calling emergency services for lingual AO; gastrointestinal AO) involving actors and a volunteer parent, a workshop for learning the SC injection technique, and a satisfaction questionnaire. We analysed the answers on the questionnaire and noted down parents' verbatim observations during debriefing sessions. RESULTS: Eight parents from 5 families took part in this session. Parents rated their overall satisfaction as 9.3/10. The parents commented that during the simulations, they felt "in the thick of it" and that they "experienced stress while viewing the scenes", thus attesting to the realism and relevance of the simulated scenarios. DISCUSSION: This session met the parents' expectations in terms of being able to cope and having adequate know-how, based on both the simulations and the level of knowledge acquired. The main limitation lay in the parents' difficulty in confronting certain situations reminiscent of traumatic past experiences. TTS shares many common features with SH for the parents of sick children. The place of the latter in TTS must be evaluated.


Assuntos
Angioedemas Hereditários/tratamento farmacológico , Antagonistas de Receptor B2 da Bradicinina/administração & dosagem , Bradicinina/análogos & derivados , Pais/educação , Treinamento por Simulação , Adolescente , Bradicinina/administração & dosagem , Criança , Pré-Escolar , Feminino , Humanos , Injeções Subcutâneas , Masculino , Índice de Gravidade de Doença
4.
J Gynecol Obstet Hum Reprod ; 47(3): 101-106, 2018 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-29292236

RESUMO

BACKGROUND: Laparoscopic skills are more and more often being learned on simulators. PURPOSE: To assess the respective roles of observation and direct practice in the retention of laparoscopic procedural skills. BASIC PROCEDURES: Twelve surgical residents were included in a two-session laparoscopic training course. During the first session (S1), one participant completed a cholecystectomy on the Simbionix LAPMentor™ and then observed his colleague carrying out a total hysterectomy and vice versa. During the second session (S2), each participant completed both interventions. Skills evaluation was assessed using the Objective Structured Assessment of Technical Skills (OSATS) global rating scale and LAPMentor™ metrics. MAIN FINDINGS: Mean OSATS score during the first session was 19.3±5.1, and increased by 37% in the group of former observer students (S2O, P=0.003), and by 54% in the group of former practising students (S2A, P=0.001). Self- and peer-grading results were concordant with the supervisor's evaluation. Detailed analysis of LAPMentor™ metrics showed a trend toward more parameters being improved in group S2A as compared to group S2O on both interventions. The most significant improvements concerned the time of completion for the hysterectomy and the efficiency of cautery for the cholecystectomy. CONCLUSIONS: Observation of laparoscopic skills still allows for surgical improvement, but direct practice on a virtual reality trainer provides better results. Self- and peer-grading were concordant with the supervisor's evaluation. This work may advocate the integration of both personal training on simulators and surgical observation into residents' surgical curricula.


Assuntos
Competência Clínica , Cirurgia Geral/educação , Histerectomia/educação , Laparoscopia/educação , Treinamento por Simulação/métodos , Realidade Virtual , Adulto , Colecistectomia Laparoscópica/educação , Avaliação Educacional , Humanos , Internato e Residência
5.
J Gynecol Obstet Biol Reprod (Paris) ; 45(7): 679-84, 2016 Sep.
Artigo em Francês | MEDLINE | ID: mdl-26996238

RESUMO

OBJECTIVES: To evaluate the benefits of training sessions for pelvic examination using anatomic models. MATERIAL AND METHODS: The medical students (MS) registered in their 5th year of medical studies at Angers University Hospital had to complete two anonymous questionnaires; one at the beginning of the workshop and one at the end. Every procedure which included pelvic exam (PE), vaginal sample (VS), smear test (ST), insertion of a speculum and insertion of intra-uterine device (IUD) was evaluated. RESULTS: Seventy-one MS answered both questionnaires. They were very satisfied or satisfied with the outcomes of the workshop in 91 % of the cases. At the beginning of the workshop, 28 %, 52 %, 30 %, 25 % and 3 % reported a low level of difficulty to carry out, respectively, a PE, VS, ST, insertion of a speculum, insertion of an IUD. At the end of the session, there were respectively 55 %, 83 %, 76 %, 66 % and 16 % of MS to report a low level of difficulty of these same procedures. For all of these procedures, there were a significant (P<0.05) number of MS who estimated the procedure's level of difficulty as being low at the end of the session. CONCLUSION: The level of technical difficulty of all procedures was significantly decreased at the end of the workshop.


Assuntos
Educação Médica/métodos , Exame Ginecológico/métodos , Ginecologia/educação , Modelos Anatômicos , Treinamento por Simulação/métodos , Estudantes de Medicina , Adulto , Feminino , Humanos , Masculino , Pessoa de Meia-Idade
6.
Fundam Clin Pharmacol ; 3(4): 329-35, 1989.
Artigo em Inglês | MEDLINE | ID: mdl-2553566

RESUMO

The effects of two inhibitors of angiotensin I converting enzyme, captopril and enalapril, on the concentrations of Na, K, Ca, Mg, Fe, S, P, Sr, Mn, Cu and Zn ions in blood, plasma, heart, skeletal muscle, liver and kidney of spontaneously hypertensive rats (SHR) were studied. Captopril and enalapril were given by the intraperitoneal route for 15 days, at 160 mumols/kg/d and 40 mumols/kg/d, respectively. Elements in tissues were determined by inductively coupled plasma emission spectrometry with a JY 48 instrument. The common changes produced with the two drugs were: a decrease of Na in muscle (-10%), a decrease of Ca in plasma and kidney (less than -10%) and a decrease of Mn in liver (-15%). The main effects observed with only one of the two drugs were: an increase of Cu in plasma (+26%) with captopril, and increases of Sr in heart (+56%), muscle (+79%) and liver (+74%) with enalapril. Zinc concentration in tissues was not modified, except for an increase in liver with captopril (+13%) and a decrease in heart with enalapril (-11%).


Assuntos
Captopril/farmacologia , Enalapril/farmacologia , Oligoelementos/metabolismo , Animais , Pressão Sanguínea/efeitos dos fármacos , Masculino , Ratos , Ratos Endogâmicos SHR , Oligoelementos/sangue
7.
Therapie ; 44(1): 5-7, 1989.
Artigo em Francês | MEDLINE | ID: mdl-2734721

RESUMO

Ornidazole was administered for ten days to twelve hospitalized neonates at the same daily dose of 20 mg/kg either by one or two IV infusions. Minimum steady-state concentrations measured between the 4th and 10th day ranged from 7.8 to 17.3 (mean = 11.8 +/- 3.2 mg/l) for one daily infusion and from 10.9 to 26.6 (mean = 20.5 +/- 6 mg/l) for two infusions. These minimum concentrations were all above the minimum inhibitory concentration for the most clinically significant anaerobic bacteria. So the single daily administration of ornidazole at the dose of 20 mg/kg is sufficient to obtain therapeutic efficiency.


Assuntos
Nitroimidazóis/sangue , Ornidazol/sangue , Infecções Bacterianas/sangue , Doenças do Sistema Digestório/sangue , Humanos , Lactente , Recém-Nascido , Infusões Intravenosas , Ornidazol/administração & dosagem , Fatores de Tempo
8.
Therapie ; 48(4): 393-6, 1993.
Artigo em Francês | MEDLINE | ID: mdl-8128422

RESUMO

We investigated acetaminophen pharmacokinetics in CSF in twelve operated arteritics patients with continuous spinal anesthesia. Nine men and three women aged 77 +/- 7 years and weighing 66 +/- 15 kg entered in the study after expressing verbal informed consent. They received intravenously a single dose of acetominophen (equivalent to 1 g). Fifteen minutes to six hours after the intravenous injection, blood and CSF samples were withdrawn every thirty minutes, except during the second to the third hour were it was every fifteen minutes. Acetaminophen concentrations in blood and in CSF were assayed by HPLC. Acetaminophen was detected in the earliest samples (1.32 +/- 1.32 micrograms.ml-1) and then increased up to 8.16 +/- 3.04 micrograms.ml-1 at 186 +/- 56 minutes. From 135th to 345th minute, acetaminophen concentration in CSF stay at about 6 micrograms.ml-1, which is the duration of its maximal analgesic central effect.


Assuntos
Acetaminofen/líquido cefalorraquidiano , Envelhecimento/fisiologia , Acetaminofen/farmacocinética , Idoso , Idoso de 80 Anos ou mais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade
9.
Arch Pediatr ; 2(5): 456-9, 1995 May.
Artigo em Francês | MEDLINE | ID: mdl-7640739

RESUMO

BACKGROUND: Pyknodysostosis is characterized by post-natal onset of short-limbed short stature and generalized hyperostosis. It must be differentiated from osteopetrosis with precocious manifestations in which hyperostosis may crowd the marrow cavity with extramedullary hematopoiesis. CASE REPORTS: A boy, born from consanguineous parents presented with classical features of pyknodysostosis: short-limbed stature, large skull, frontal bossing, wide anterior fontanelle and tendency to fracture. His sister had the same features at the age of 3 months; she had hepatosplenomegaly at the age of 5 months with anemia, erythroblastosis (13%), myelemia and, at 10 months, thrombocytopenia. CONCLUSION: Hyperosostis can be complicated by development of such severe hematological manifestations as classically seen in osteopetrosis. Differential diagnosis between both entities is based upon radioclinical investigation.


Assuntos
Disostose Craniofacial/sangue , Disostose Craniofacial/genética , Nanismo/genética , Hiperostose/genética , Osteopetrose/genética , Disostose Craniofacial/diagnóstico , Nanismo/sangue , Feminino , Doenças Hematológicas/etiologia , Hematopoese Extramedular , Humanos , Hiperostose/sangue , Lactente , Recém-Nascido , Masculino , Osteopetrose/sangue
10.
Ann Fr Anesth Reanim ; 10(2): 127-36, 1991.
Artigo em Francês | MEDLINE | ID: mdl-2058831

RESUMO

Transcranial Doppler sonography (TCD) is a non invasive technique whereby ultrasonic signals may be recorded from the basal cerebral arteries by using a low frequency probe. Three routes can be used: the transtemporal approach, which studies the anterior, middle and posterior cerebral arteries; the transorbital approach, which evaluates the ophthalmic artery and the carotid canal; and the sub-occipital approach, which assesses the basilar, posterior cerebral and intracranial vertebral arteries. Normal reference values for Doppler parameters have been established for these arteries. Many factors influence them, such as the diameter of the examined blood vessel, PaCO2, cerebral blood flow and cerebrovascular resistances. There are numerous clinical applications of TCD. In anaesthesia, monitoring with this method is useful during cardiopulmonary bypass, controlled hypotension, or carotid endarterectomy. After subarachnoid haemorrhage, the degree of vasospasm can be assessed by TCD. Monitoring cerebral blood flow velocities in intensive care provides important information for the treatment of patients suffering from meningitis, or experienced a head injury, or another ischaemic-anoxic disease. The field of clinical applications of TCD is increasing greatly, but the results must always be carefully interpreted, taking into account the data of other investigations.


Assuntos
Anestesia , Lesões Encefálicas/diagnóstico por imagem , Cuidados Críticos , Ecoencefalografia , Morte Encefálica/diagnóstico , Doenças das Artérias Carótidas/cirurgia , Circulação Cerebrovascular , Humanos , Hipóxia Encefálica/diagnóstico por imagem , Neurocirurgia , Reprodutibilidade dos Testes
11.
Ann Fr Anesth Reanim ; 8(6): 650-5, 1989.
Artigo em Francês | MEDLINE | ID: mdl-2699174

RESUMO

The diagnosis of adrenal haemorrhage complicating heparin therapy is often delayed, despite computed tomography (CT). Moreover, its pathogenesis is not clear. Adrenal haemorrhages are often seen in cases where there is no unduly excessive anticoagulation, and can be accompanied by a paradoxical thrombosis of the central adrenal vein. Symptoms usually occur within the first 8 to 12 days after starting heparin. The difficulty in establishing the diagnosis stems from the fact that symptoms are rather nonspecific: abdominal pain and backache, nausea, vomiting, lethargy, weakness, hypotension, hyperpyrexia. To confirm the diagnosis, both hormonal proof of adrenal failure and anatomic evidence of haemorrhage must be found. Early CT scans may show the haemorrhage. Several possible causes have been put forward to account for these adrenal haemorrhages. The degree of anticoagulation did not seem to be a prerequisite, 30 to 50% of patients showing no evidence of other bleeding or coagulation tests outside the therapeutic range. Capillary fragility of old age might be a factor. Stress would seem to be an important factor predisposing to adrenal haemorrhage. Many authors consider the paradoxical central vein thrombosis as a result of the haemorrhage rather than its cause, whereas other conclude the opposite. Unfortunately, to date coagulation studies are often incomplete; platelet counts were missing in most reports published before 1985. Since that date, a heparin induced thrombosis-thrombocytopaenia syndrome (HITTS), in which thrombosis may occur in any vascular bed, has been recognized with increasing frequency. Nine cases of adrenal haemorrhage associated with HITTS have been reported. It seems highly likely that a proportion of cases of heparin-related adrenal destruction are due to HITTS.(ABSTRACT TRUNCATED AT 250 WORDS)


Assuntos
Doenças das Glândulas Suprarrenais/induzido quimicamente , Glândulas Suprarrenais/irrigação sanguínea , Hematoma/induzido quimicamente , Heparina/efeitos adversos , Doenças das Glândulas Suprarrenais/diagnóstico , Doenças das Glândulas Suprarrenais/terapia , Transtornos da Coagulação Sanguínea/fisiopatologia , Testes de Coagulação Sanguínea , Hematoma/diagnóstico , Hematoma/terapia , Humanos , Hiponatremia/etiologia , Trombocitopenia/fisiopatologia , Tomografia Computadorizada por Raios X
12.
Ann Fr Anesth Reanim ; 13(2): 153-7, 1994.
Artigo em Francês | MEDLINE | ID: mdl-7818196

RESUMO

This prospective randomized single-blind study compared the efficacy of a combination of propacetamol (2 g) and a low dose of nalbuphine hydrochloride (10 mg) with nalbuphine hydrochloride (20 mg) alone, in a population of 152 white female patients after gynaecologic or obstetrical surgery, for alleviation of postoperative pain in recovery room. The drugs were administered intravenously in case of pain. The population was divided into two groups: group 1 received 20 mg of nalbuphine hydrochloride and group 2 received 2 g of propacetamol combined with 10 mg of nalbuphine hydrochloride. The pain intensity was studied with the visual analogue scale and comparisons use no parametric tests (Mann and Whitney test, Kruskall and Wallis test) and Chi2 test. Groups were similar for age, surgical and anaesthesia procedures and initial pain level. The propacetamol-nalbuphine hydrochloride 10 mg association provided a significantly better analgesia than nalbuphine 20 mg during the first two postoperative hours (p < 0.05). In group 1, the analgesia score decrease was respectively 28 +/- 25 mm (range: 33-75 mm) after 1 h and 31 +/- 25 mm (range: 26-84 mm) after 2 h. In group 2, the decrease was more important: 37 +/- 21 mm (range: 5-84 mm) after 1 h and 42 +/- 23 mm (range: 20-84 mm) after 2 h. Side effects were minimal and similar in both groups (nausea, drowsiness). It is concluded that a propacetamol-nalbuphine hydrochloride 10 mg association provides better analgesia than single dose of 20 mg of nalbuphine. This association convenient analgesia with a decreased dose of nalbuphine.


Assuntos
Acetaminofen/análogos & derivados , Analgésicos/uso terapêutico , Nalbufina/uso terapêutico , Dor Pós-Operatória/tratamento farmacológico , Acetaminofen/uso terapêutico , Adulto , Cesárea , Combinação de Medicamentos , Feminino , Doenças dos Genitais Femininos/cirurgia , Humanos , Histerectomia , Laparotomia , Pessoa de Meia-Idade , Medição da Dor , Gravidez
13.
Ann Fr Anesth Reanim ; 17(3): 227-33, 1998.
Artigo em Francês | MEDLINE | ID: mdl-9750734

RESUMO

OBJECTIVE: To assess in children with a transcranial Doppler the effect on cerebral blood flow velocities of desflurane, whose cerebral vasodilator effects have been studied in animals and in adults with intracranial lesions. STUDY DESIGN: Prospective clinical study. PATIENTS: Ten healthy children, mean age: 3.4 yr, ASA physical class 1, undergoing minor urologic surgery, were included in this study. METHOD: Induction was obtained with atropine 10 micrograms.kg-1, fentanyl 3 micrograms.kg-1 and propofol 3 mg.kg-1. Endotracheal intubation was facilitated by atracurium 0.3 mg.kg-1. Mechanical ventilation, with a 50% air/oxygen mixture was adjusted to achieve an end-tidal CO2 (PETCO2) level of 38 +/- 2 mmHg. Monitoring included measurement of mean arterial blood pressure (MAP), heart rate, PETCO2, SpO2 and end-tidal desflurane concentrations (FETDes). Mean blood flow velocities (Vmean) were measured in the middle cerebral artery using a bi-directional 2 MHz TCD system (EME-TC 2000 S). A first TCD measurement followed intubation (T1). Thereafter, desflurane was adjusted to 1 MAC. Six other TCDs were recorded each minute until FETDes reached the inspired fraction (T2-T7). Thereafter, CO2 reactivity was assessed with a hypocapnia test, induced by hyperventilation. Measures were done at T8 (PETCO2: 33 +/- 1 mmHg), T9 (PETCO2: 29 +/- 1 mmHg), and T10 (initial PETCO2: 38 +/- 1 mmHg). All these measurements were made before starting surgery. Analysis of variance (ANOVA) was used to analyse the data (P < 0.05 was considered as significant). RESULTS: The Vmean and heart rate increased significantly with increasing concentrations of desflurane (Vmean from 68 +/- 27 to 106 +/- 30 cm.s-1 and heart rate from 109 +/- 17 to 136 +/- 15 b.min-1 between T1 and T7). During hypocapnia, Vmean decreased to 68 +/- 23 cm.s-1 at T9, and returned to normal values with PETCO2 at 38 mmHg at T10. SpO2 remained unchanged. Mean arterial pressure was stable from T1 to T7, but decreased significantly at T9 and T10. CONCLUSION: Desflurane elicits a dose-dependent increase in cerebral blood flow velocities and heart rate, but does not change mean arterial pressure, suggesting that its cerebrovascular action is independent of its systemic vascular action. CO2 reactivity is maintained at one MAC. The results in children are similar to those seen in adults.


Assuntos
Anestésicos Inalatórios/farmacologia , Velocidade do Fluxo Sanguíneo/efeitos dos fármacos , Dióxido de Carbono/farmacologia , Circulação Cerebrovascular/efeitos dos fármacos , Isoflurano/análogos & derivados , Adulto , Análise de Variância , Anestésicos Inalatórios/administração & dosagem , Anestésicos Intravenosos/administração & dosagem , Pressão Sanguínea/efeitos dos fármacos , Dióxido de Carbono/metabolismo , Artérias Cerebrais/diagnóstico por imagem , Artérias Cerebrais/efeitos dos fármacos , Pré-Escolar , Desflurano , Relação Dose-Resposta a Droga , Feminino , Fentanila/administração & dosagem , Frequência Cardíaca/efeitos dos fármacos , Humanos , Hiperventilação/fisiopatologia , Hipocapnia/fisiopatologia , Isoflurano/administração & dosagem , Isoflurano/farmacologia , Masculino , Procedimentos Cirúrgicos Menores , Oxigênio/sangue , Propofol/administração & dosagem , Estudos Prospectivos , Volume de Ventilação Pulmonar , Ultrassonografia Doppler Transcraniana , Procedimentos Cirúrgicos Urológicos , Vasodilatação/efeitos dos fármacos
14.
Ann Fr Anesth Reanim ; 14(5): 406-16, 1995.
Artigo em Francês | MEDLINE | ID: mdl-8572407

RESUMO

Magnesium (Mg), a cofactor in numerous enzymatic reactions, is often ignored by clinicians, as the symptomatology of Mg depletion is not specific and usually associated with that of the cause of the depletion. Furthermore, the plasma Mg concentration (0.8 to 1.1 mmol.L-1) is only equivalent to one percent of the total body content. A Mg deficit may exist while plasma Mg concentration is normal. Therefore other techniques for Mg assessment, such as the repletion test, as well as red blood cell and lymphocyte concentrations have been used. A renewed interest for Mg occurred as numerous studies have shown the therapeutic efficiency of Mg and as the mechanisms of its haemodynamic effects have been recognized. Mg regulates Na-K-ATPase activity, K channels activity and, most of all, it is a natural calcium channel blocking agent. These properties explain its important place in electrophysiology of myocardial cells and the effects on the tension of smooth muscles, resulting in a vasodilation and a bronchodilation respectively. The antagonistic effect of Mg on calcium decreases the presynaptic release of acetylcholine at the neuromuscular junction and the release of epinephrine at the peripheral sympathetic nerves and the adrenals. Mg potentiates the effect of non-depolarizing muscle relaxants. A Mg deficiency occurs often in ICU patients, in alcoholics and during use of diuretics. Simultaneous administration of Mg is often required for treatment of potassium deficiency. Mg has an anti-arrhythmic effect towards digoxin-mediated dysrhythmias and torsades de pointes, and can be efficient in other arrhythmias. Systematic use of Mg seems to decrease mortality of acute myocardial infarction and is justified during cardiac surgery, often associated with hypomagnesemia, because of vasodilation of coronary arteries and in order to prevent occurrence of arrhythmias. Mg, because of its calcium channel blocking properties and as it lowers the release of epinephrine, is indicated for surgery of pheochromocytoma. In eclamptic and pre-eclamptic patients, the use of Mg is valuable, but not as an anti-epileptic agent. Other clinical uses of Mg have been proposed, but they are either anecdotal or of uncertain efficiency.


Assuntos
Anestesia , Cuidados Críticos , Deficiência de Magnésio , Magnésio/fisiologia , Fenômenos Fisiológicos Cardiovasculares , Sistema Nervoso Central/fisiologia , Humanos , Magnésio/sangue , Cloreto de Magnésio/uso terapêutico , Deficiência de Magnésio/diagnóstico , Deficiência de Magnésio/etiologia , Sulfato de Magnésio/uso terapêutico , Placa Motora/fisiologia
15.
Ann Fr Anesth Reanim ; 6(5): 429-33, 1987.
Artigo em Francês | MEDLINE | ID: mdl-3434888

RESUMO

The efficacy of transcutaneous pacing was studied in 33 patients during general anaesthesia. The temporary pacing was effective in all cases. Stimulation thresholds ranged from 85 to 150 mA (mean : 110 +/- 17). In all 33 patients, external pacing was effective in producing a pulse without significantly reducing arterial pressure. Stimulation thresholds were only influenced by electrode position; age, weight, thoracic diameter and cardiothoracic ratio did not have any effect on them. No adverse effects of transcutaneous pacing were recorded. Transcutaneous pacing can be an alternative to transvenous right ventricular endocardiac pacing in the operating room in some circumstances.


Assuntos
Anestesia Geral , Estimulação Cardíaca Artificial , Idoso , Idoso de 80 Anos ou mais , Eletrocardiografia , Feminino , Bloqueio Cardíaco/terapia , Hemodinâmica , Humanos , Período Intraoperatório , Masculino , Pessoa de Meia-Idade
16.
Ann Fr Anesth Reanim ; 6(4): 313-9, 1987.
Artigo em Francês | MEDLINE | ID: mdl-3498406

RESUMO

Twenty patients undergoing cystoscopy (group A) and forty patients undergoing transurethral resection (group B), aged more than 65 years, were anaesthetized. Duration of anaesthesia was less than 15 min for cystoscopy, and more than 30 min for transurethral resection. No premedication was given. The patients were ASA I or ASA II. Group A patients were allocated randomly to receive either 1.5 mg . kg-1 propofol (n = 10) or 2 mg . kg-1 methohexitone (n = 10) for induction of anaesthesia. Anaesthesia was maintained using incremental doses of propofol or methohexitone and 60% N2O with a face-mask. Forty group B patients undergoing transurethral resection were randomly assigned to four equal groups (PB: propofol 1.5 mg . kg-1; MB: methohexitone 2 mg . kg-1; PF: propofol and 1.5 micrograms . kg-1 fentanyl; PFV: propofol, 2 micrograms . kg-1 fentanyl and 0.1 mg . kg-1 vecuronium). Suxamethonium (1 mg . kg-1; groups PB, MB and PF) and vecuronium (0.1 mg . kg-1; group PFV) were given to facilitate endotracheal intubation. Anaesthesia was maintained by infusion of propofol or methohexitone, using a calibrated pump started immediately after intubation. Ventilation was controlled only in group PFV. Induction with 1.5 mg . kg-1 propofol resulted in stopping counting after 62 s and loss of the eye-lash reflex after 84 s versus 47 and 67 s respectively with methohexitone. The anaesthesist's assessment was favourable for cystoscopy with propofol and methohexitone; recovery times were similar for the two drugs in cystoscopy lasting less than 30 min.(ABSTRACT TRUNCATED AT 250 WORDS)


Assuntos
Anestésicos , Cistoscopia , Metoexital , Fenóis , Prostatectomia , Idoso , Anestesia Geral , Feminino , Hemodinâmica/efeitos dos fármacos , Humanos , Masculino , Propofol , Distribuição Aleatória , Respiração/efeitos dos fármacos
17.
Ann Fr Anesth Reanim ; 6(2): 79-82, 1987.
Artigo em Francês | MEDLINE | ID: mdl-3592319

RESUMO

The haemodynamic changes due to cross-clamping of the abdominal aorta below the renal arteries were studied in ten patients. Anaesthesia was induced with thiopentone and maintained with fentanyl and vecuronium and inhalation of 60% nitrous oxide in oxygen. At the fifth minute, clamping increased mean arterial pressure (Pa) by 11%, systemic vascular resistance (Rsa) by 26% and decreased cardiac output (CO) by 20%. Nifedipine was administered intranasally at this time. Heart rate remained unchanged; mean pulmonary arterial and mean pulmonary wedge pressures were slightly decreased. Pa and Rsa fell to significantly lower levels between the fifth and fifteenth minutes (24 and 43% respectively). Although CO increased by 28%, this was not significant. The administration of intranasal nifedipine during anaesthesia was well tolerated. This study demonstrated that intranasal nifedipine prevented adverse haemodynamic effects of cross-clamping of the aorta below the renal arteries.


Assuntos
Aorta Abdominal/cirurgia , Hemodinâmica/efeitos dos fármacos , Nifedipino/farmacologia , Administração Intranasal , Anestesia Geral , Constrição , Feminino , Humanos , Masculino , Nifedipino/administração & dosagem
18.
Ann Fr Anesth Reanim ; 8(6): 662-6, 1989.
Artigo em Francês | MEDLINE | ID: mdl-2517382

RESUMO

A case of pseudo von Willebrand's disease occurring in a 26 year old pregnant woman is reported. The diagnosis was made during the 33rd week of pregnancy. The patient had excessive bleeding of minor wounds, and biological tests revealed a bleeding time exceeding 20 min, a greatly reduced level of Rco fraction of von Willebrand's factor (27%), the absence of high molecular weight von Willebrand's factor multimers, and a greatly increased platelet aggregation in small doses of ristocetin. The patient was allowed to give birth by the vaginal route, receiving 30 IU.kg-1 highly purified concentrated factor VIII, once cervical dilatation was complete. Uterine revision was carried out for safety's sake because of prolonged post-partum bleeding. Two red cell packs were transfused as haemoglobin concentration decreased from 106 g.l-1 to 80 g.l-1. The newborn also presented with biological signs of pseudo von Willebrand's disease, with a bleeding time exceeding 15 min, hypothrombocytopaenia, and a level of Rco fraction of von Willebrand's factor of 9%. Preoperative assessment should always include an investigation of primary haemostatic mechanisms. In case of pseudo von Willebrand's disease, platelet transfusion combined or not with the transfusion of highly purified factor VIII seems to be useful. Investigation of other family members for a pseudo von Willebrand's disease trait is essential.


Assuntos
Doenças de von Willebrand/sangue , Fator de von Willebrand/análise , Adulto , Testes de Coagulação Sanguínea , Eletroforese em Gel de Ágar , Fator VIII/administração & dosagem , Feminino , Hemostasia , Humanos , Recém-Nascido , Contagem de Plaquetas , Gravidez , Doenças de von Willebrand/genética
19.
Ann Fr Anesth Reanim ; 22(4): 366-8, 2003 Apr.
Artigo em Francês | MEDLINE | ID: mdl-12818332

RESUMO

A case of intestinal gas explosion during the course of carcinologic surgery in a 51-year-old patient is reported. This accident, often dramatic, has become exceptional since the use of mannitol for colonic preparation has disappeared. This incident occurred during the course of a total pelvic exenteration performed under general anaesthesia with inhalation of both a mixture oxygen-nitrous oxide and volatile agents. The colon incision with an electrocautery was contemporaneous with a violent deflagration accountable for organic lesions. This case report reminds us that the risk of a dangerous explosion persists in relation with surgical, anaesthetic and individual risk factors.


Assuntos
Adenocarcinoma/cirurgia , Anestesia por Inalação/efeitos adversos , Neoplasias Colorretais/cirurgia , Explosões , Anestésicos Inalatórios , Diuréticos Osmóticos/uso terapêutico , Eletrocoagulação/efeitos adversos , Humanos , Masculino , Manitol/uso terapêutico , Pessoa de Meia-Idade , Óxido Nitroso , Oxigênio , Exenteração Pélvica
20.
Ann Fr Anesth Reanim ; 22(10): 856-60, 2003 Dec.
Artigo em Francês | MEDLINE | ID: mdl-14644366

RESUMO

OBJECTIVES: To analyse the results of delayed evaluation of European teaching sessions using a questionnaire provided by the French College of Anaesthesiologists. STUDY DESIGN: Open evaluation. MATERIAL: Questionnaires were completed 3-6 months after European courses provided in November-December 1999. METHOD: The types of professional exercise and the medical practice as well as the theme of the courses were pointed out. The evaluation included six items noted from 1 to 10: usefulness of the abstract book, discussion with colleagues, discussion with a manager, decision to modify medical practice, application of that decision, own objectives fulfilled. The global mean score for each item was calculated. Results were compared according to the professional mode of exercise and the theme of the course. RESULTS: 5/7 centres provided information. 91/239 questionnaires were returned to the organizers. The participants were working in different structures (private clinic: 25, university hospital: 31, general hospital: 27, PSPH: 8). The main exercise was anaesthesiology (75/77 answers). Means scores affected to the different items were around 7 for all but one of them. The mean score concerning discussion with a manager was significantly decreased to 3.5 +/- 3.2. Decision to modify their own practise was higher in private clinics compared to PSPH. The abstract book was more consulted after the first course (respiration and thorax). CONCLUSION: 3-6 months following the FEEA courses the participants thought to have fulfil their objectives and declared to have modify their medical practise. The lack of discussion with a manager should be analysed.


Assuntos
Educação Médica Continuada/normas , Anestesiologia/educação , Coleta de Dados , Europa (Continente) , Avaliação de Programas e Projetos de Saúde , Inquéritos e Questionários
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