Detalhe da pesquisa
1.
Microglia jointly degrade fibrillar alpha-synuclein cargo by distribution through tunneling nanotubes.
Cell
; 184(20): 5089-5106.e21, 2021 09 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-34555357
2.
Microglial PD-1 stimulation by astrocytic PD-L1 suppresses neuroinflammation and Alzheimer's disease pathology.
EMBO J
; 40(24): e108662, 2021 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34825707
3.
NLRP3 inflammasome activation drives tau pathology.
Nature
; 575(7784): 669-673, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31748742
4.
Characterizing microglial senescence: Tau as a key player.
J Neurochem
; 166(3): 517-533, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37278117
5.
NLRP3-directed antisense oligonucleotides reduce microglial immunoactivities in vitro.
J Neurochem
; 2023 Feb 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-36799439
6.
Microglial NLRP3 Inflammasome Activation upon TLR2 and TLR5 Ligation by Distinct α-Synuclein Assemblies.
J Immunol
; 207(8): 2143-2154, 2021 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34507948
7.
Microglia-derived ASC specks cross-seed amyloid-ß in Alzheimer's disease.
Nature
; 552(7685): 355-361, 2017 12 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-29293211
8.
Inhibition of formyl peptide receptors improves the outcome in a mouse model of Alzheimer disease.
J Neuroinflammation
; 17(1): 131, 2020 Apr 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-32331524
9.
NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice.
Nature
; 493(7434): 674-8, 2013 Jan 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-23254930
10.
PPARγ/RXRα-induced and CD36-mediated microglial amyloid-ß phagocytosis results in cognitive improvement in amyloid precursor protein/presenilin 1 mice.
J Neurosci
; 32(48): 17321-31, 2012 Nov 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-23197723
11.
Mrp14 deficiency ameliorates amyloid ß burden by increasing microglial phagocytosis and modulation of amyloid precursor protein processing.
J Neurosci
; 32(49): 17824-9, 2012 Dec 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-23223301