Detalhe da pesquisa
1.
Cytosolic calcium: Judge, jury and executioner of neurodegeneration in Alzheimer's disease and beyond.
Alzheimers Dement
; 19(8): 3701-3717, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37132525
2.
Calcium Dyshomeostasis Drives Pathophysiology and Neuronal Demise in Age-Related Neurodegenerative Diseases.
Int J Mol Sci
; 24(17)2023 Aug 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-37686048
3.
Evaluation of Distance Metrics and Spatial Autocorrelation in Uniform Manifold Approximation and Projection Applied to Mass Spectrometry Imaging Data.
Anal Chem
; 91(9): 5706-5714, 2019 05 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30986042
4.
Pharmacological modulation of septins restores calcium homeostasis and is neuroprotective in models of Alzheimer's disease.
Science
; 384(6699): eadd6260, 2024 May 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-38815015
5.
Evaluation of the Vitotox and RadarScreen assays for the rapid assessment of genotoxicity in the early research phase of drug development.
Mutat Res
; 676(1-2): 113-30, 2009 May 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-19393335
6.
Modifying Rap1-signalling by targeting Pde6δ is neuroprotective in models of Alzheimer's disease.
Mol Neurodegener
; 13(1): 50, 2018 09 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-30257685
7.
A yeast-based model of alpha-synucleinopathy identifies compounds with therapeutic potential.
Biochim Biophys Acta
; 1762(3): 312-8, 2006 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-16413174
8.
Targeting disease, not disease targets: Innovative approaches in tackling neurodegenerative disorders.
IDrugs
; 10(4): 259-63, 2007 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-17390249
9.
Characterization of alpha-synuclein aggregation and synergistic toxicity with protein tau in yeast.
FEBS J
; 272(6): 1386-400, 2005 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-15752356
10.
Derailed intraneuronal signalling drives pathogenesis in sporadic and familial Alzheimer's disease.
Biomed Res Int
; 2014: 167024, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25243118
11.
Substituted 2-aminothiazoles are exceptional inhibitors of neuronal degeneration in tau-driven models of Alzheimer's disease.
Eur J Pharm Sci
; 43(5): 386-92, 2011 Aug 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-21664968
12.
Pathological Hallmarks, Clinical Parallels, and Value for Drug Testing in Alzheimer's Disease of the APP[V717I] London Transgenic Mouse Model.
Int J Alzheimers Dis
; 20102010 Sep 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-20862386
13.
PKA and Sch9 control a molecular switch important for the proper adaptation to nutrient availability.
Mol Microbiol
; 55(3): 862-80, 2005 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-15661010
14.
Molecular mechanisms controlling the localisation of protein kinase A.
Curr Genet
; 41(4): 199-207, 2002 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-12172960
15.
Feedback inhibition on cell wall integrity signaling by Zds1 involves Gsk3 phosphorylation of a cAMP-dependent protein kinase regulatory subunit.
J Biol Chem
; 278(26): 23460-71, 2003 Jun 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-12704202