Detalhe da pesquisa
1.
Midbrain organoids mimic early embryonic neurodevelopment and recapitulate LRRK2-p.Gly2019Ser-associated gene expression.
Am J Hum Genet
; 109(2): 311-327, 2022 02 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35077669
2.
Stress hormone signalling inhibits Th1 polarization in a CD4 T-cell-intrinsic manner via mTORC1 and the circadian gene PER1.
Immunology
; 165(4): 428-444, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35143696
3.
Single-cell transcriptomics reveals multiple neuronal cell types in human midbrain-specific organoids.
Cell Tissue Res
; 382(3): 463-476, 2020 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-32737576
4.
Patient-derived organoids and orthotopic xenografts of primary and recurrent gliomas represent relevant patient avatars for precision oncology.
Acta Neuropathol
; 140(6): 919-949, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33009951
5.
New insights into the early mechanisms of epileptogenesis in a zebrafish model of Dravet syndrome.
Epilepsia
; 61(3): 549-560, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32096222
6.
CaSiAn: a Calcium Signaling Analyzer tool.
Bioinformatics
; 34(17): 3052-3054, 2018 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29668830
7.
Single cell transcriptome analysis of the THY-Tau22 mouse model of Alzheimer's disease reveals sex-dependent dysregulations.
Cell Death Discov
; 10(1): 119, 2024 Mar 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-38453894
8.
Glioblastoma-instructed microglia transition to heterogeneous phenotypic states with phagocytic and dendritic cell-like features in patient tumors and patient-derived orthotopic xenografts.
Genome Med
; 16(1): 51, 2024 Apr 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38566128
9.
Single-cell transcriptomics of NRAS-mutated melanoma transitioning to drug resistance reveals P2RX7 as an indicator of early drug response.
Cell Rep
; 42(7): 112696, 2023 07 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-37379213
10.
Glioblastoma-instructed microglia transition to heterogeneous phenotypic states with phagocytic and dendritic cell-like features in patient tumors and patient-derived orthotopic xenografts.
bioRxiv
; 2023 Dec 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36945572
11.
Early-to-mid stage idiopathic Parkinson's disease shows enhanced cytotoxicity and differentiation in CD8 T-cells in females.
Nat Commun
; 14(1): 7461, 2023 Nov 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-37985656
12.
Single-cell transcriptomics of human iPSC differentiation dynamics reveal a core molecular network of Parkinson's disease.
Commun Biol
; 5(1): 49, 2022 01 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-35027645
13.
Single-Cell Transcriptional Profiling and Gene Regulatory Network Modeling in Tg2576 Mice Reveal Gender-Dependent Molecular Features Preceding Alzheimer-Like Pathologies.
Mol Neurobiol
; 2022 Aug 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-35980567
14.
Elucidating tumour-associated microglia/macrophage diversity along glioblastoma progression and under ACOD1 deficiency.
Mol Oncol
; 16(17): 3167-3191, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35838338
15.
Combinatorial analysis reveals highly coordinated early-stage immune reactions that predict later antiviral immunity in mild COVID-19 patients.
Cell Rep Med
; 3(4): 100600, 2022 04 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-35480624
16.
Single-Cell Transcriptomics and In Situ Morphological Analyses Reveal Microglia Heterogeneity Across the Nigrostriatal Pathway.
Front Immunol
; 12: 639613, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33854507
17.
Single-nuclei chromatin profiling of ventral midbrain reveals cell identity transcription factors and cell-type-specific gene regulatory variation.
Epigenetics Chromatin
; 14(1): 43, 2021 09 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34503558
18.
The Parkinson's-disease-associated mutation LRRK2-G2019S alters dopaminergic differentiation dynamics via NR2F1.
Cell Rep
; 37(3): 109864, 2021 10 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-34686322