Detalhe da pesquisa
1.
Natural mutations in the sensor kinase of the PhoPR two-component regulatory system modulate virulence of ancestor-like tuberculosis bacilli.
PLoS Pathog
; 19(7): e1011437, 2023 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-37450466
2.
Druggable redox pathways against Mycobacterium abscessus in cystic fibrosis patient-derived airway organoids.
PLoS Pathog
; 19(8): e1011559, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37619220
3.
Altered serine metabolism promotes drug tolerance in Mycobacterium abscessus via a WhiB7-mediated adaptive stress response.
Antimicrob Agents Chemother
; : e0145623, 2024 Apr 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-38651855
4.
Mycobacteria-host interactions in human bronchiolar airway organoids.
Mol Microbiol
; 117(3): 682-692, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34605588
5.
Rv0180c contributes to Mycobacterium tuberculosis cell shape and to infectivity in mice and macrophages.
PLoS Pathog
; 17(11): e1010020, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34724002
6.
Solution structure of the type I polyketide synthase Pks13 from Mycobacterium tuberculosis.
BMC Biol
; 20(1): 147, 2022 06 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-35729566
7.
The conical shape of DIM lipids promotes Mycobacterium tuberculosis infection of macrophages.
Proc Natl Acad Sci U S A
; 116(51): 25649-25658, 2019 12 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-31757855
8.
The final assembly of trehalose polyphleates takes place within the outer layer of the mycobacterial cell envelope.
J Biol Chem
; 295(32): 11184-11194, 2020 08 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32554804
9.
PGL I expression in live bacteria allows activation of a CD206/PPARγ cross-talk that may contribute to successful Mycobacterium leprae colonization of peripheral nerves.
PLoS Pathog
; 14(7): e1007151, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29979790
10.
ESX-1 and phthiocerol dimycocerosates of Mycobacterium tuberculosis act in concert to cause phagosomal rupture and host cell apoptosis.
Cell Microbiol
; 19(7)2017 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28095608
11.
Evolutionary history of tuberculosis shaped by conserved mutations in the PhoPR virulence regulator.
Proc Natl Acad Sci U S A
; 111(31): 11491-6, 2014 Aug 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-25049399
12.
The PhoP-dependent ncRNA Mcr7 modulates the TAT secretion system in Mycobacterium tuberculosis.
PLoS Pathog
; 10(5): e1004183, 2014 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-24874799
13.
Bacterial protein-O-mannosylating enzyme is crucial for virulence of Mycobacterium tuberculosis.
Proc Natl Acad Sci U S A
; 110(16): 6560-5, 2013 Apr 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-23550160
14.
Multiple deletions in the polyketide synthase gene repertoire of Mycobacterium tuberculosis reveal functional overlap of cell envelope lipids in host-pathogen interactions.
Cell Microbiol
; 16(2): 195-213, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24028583
15.
4'-Phosphopantetheinyl transferase PptT, a new drug target required for Mycobacterium tuberculosis growth and persistence in vivo.
PLoS Pathog
; 8(12): e1003097, 2012 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-23308068
16.
Detection of soluble co-factor dependent protein expression in vivo: application to the 4'-phosphopantetheinyl transferase PptT from Mycobacterium tuberculosis.
J Struct Biol
; 183(3): 320-328, 2013 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-23916562
17.
Biochemical and structural study of the atypical acyltransferase domain from the mycobacterial polyketide synthase Pks13.
J Biol Chem
; 287(40): 33675-90, 2012 Sep 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-22825853
18.
In vivo imaging of MmpL transporters reveals distinct subcellular locations for export of mycolic acids and non-essential trehalose polyphleates in the mycobacterial outer membrane.
Sci Rep
; 13(1): 7045, 2023 04 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-37120636
19.
Mycobacterium leprae phenolglycolipid-1 expressed by engineered M. bovis BCG modulates early interaction with human phagocytes.
PLoS Pathog
; 6(10): e1001159, 2010 Oct 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-20975946
20.
Spontaneous phthiocerol dimycocerosate-deficient variants of Mycobacterium tuberculosis are susceptible to gamma interferon-mediated immunity.
Infect Immun
; 79(7): 2829-38, 2011 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-21576344