Detalhe da pesquisa
1.
Nuclear Localization Signal Enhances the Targeting and Therapeutic Efficacy of a Porphyrin-Based Molecular Cargo: A Systemic In Vitro and Ex Vivo Evaluation.
Mol Pharm
; 21(5): 2351-2364, 2024 May 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38477252
2.
[99mTc]Tc-labeled HYNIC conjugated chlorambucil as a tumor targeting Agent: Synthesis, characterization and ex-vivo evaluation.
Bioorg Med Chem Lett
; 105: 129730, 2024 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38583784
3.
Formulation of patient dose of [177Lu]Lu-Trastuzumab using in-house developed freeze-dried kit: A path forward for clinical translation.
J Labelled Comp Radiopharm
; 67(4): 131-144, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38342496
4.
Synthesis and evaluation of [177 Lu]Lu-labeled porphyrin loaded PAMAM dendrimer: Impact on tumor uptake and pharmacokinetics.
Drug Dev Res
; 83(8): 1777-1790, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36112735
5.
Preparation of clinical-scale 177 Lu-Rituximab: Optimization of protocols for conjugation, radiolabeling, and freeze-dried kit formulation.
J Labelled Comp Radiopharm
; 60(5): 234-241, 2017 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28181275
6.
Evaluation of acute intravenous toxicity of HEPES: Is Good's buffer good and safe enough for clinical utilization in nuclear medicine?
Nucl Med Biol
; 132-133: 108895, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38493748
7.
Evaluation of the effect of a cell penetrating peptide (TAT) towards tailoring the targeting efficacy and tumor uptake of porphyrin.
RSC Med Chem
; 13(11): 1378-1390, 2022 Nov 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36439980
8.
Formulation and clinical translation of [177Lu]Lu-trastuzumab for radioimmunotheranostics of metastatic breast cancer.
RSC Med Chem
; 12(2): 263-277, 2021 Mar 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34046615
9.
Effect of structural variation on tumor targeting efficacy of cationically charged porphyrin derivatives: Comparative in-vitro and in-vivo evaluation for possible potential in PET and PDT.
Eur J Med Chem
; 213: 113184, 2021 Mar 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33497889
10.
Preparation of 177Lu-PSMA-617 in Hospital Radiopharmacy: Convenient Formulation of a Clinical Dose Using a Single-Vial Freeze-Dried PSMA-617 Kit Developed In-House.
Biomed Res Int
; 2021: 1555712, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34845436
11.
Preparation of [177Lu]Lu-DOTA-Ahx-Lys40-Exendin-4 for radiotherapy of insulinoma: a detailed insight into the radiochemical intricacies.
Nucl Med Biol
; 78-79: 31-40, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31731177
12.
Convenient Formulation of 68Ga-BPAMD Patient Dose Using Lyophilized BPAMD Kit and 68Ga Sourced from Different Commercial Generators for Imaging of Skeletal Metastases.
Cancer Biother Radiopharm
; 34(2): 67-75, 2019 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-30394799
13.
Preparation and evaluation of 99mTc-labeled porphyrin complexes prepared using PNP and HYNIC cores: studying the effects of core selection on pharmacokinetics and tumor uptake in a mouse model.
Medchemcomm
; 10(4): 606-615, 2019 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31057740
14.
Comparative Evaluation of Using NOTA and DOTA Derivatives as Bifunctional Chelating Agents in the Preparation of 68Ga-Labeled Porphyrin: Impact on Pharmacokinetics and Tumor Uptake in a Mouse Model.
Cancer Biother Radiopharm
; 33(1): 8-16, 2018 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-29373046
15.
Studies towards elucidating the potential of 5,10,15,20-tetrakis(p-carboxy-methyleneoxyphenyl)porphyrin as a theranostic agent for applications in PET and PDT.
Medchemcomm
; 9(4): 657-666, 2018 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30108956
16.
Effect of Number of Bifunctional Chelating Agents on the Pharmacokinetics and Immunoreactivity of 177Lu-labeled Rituximab: A Systemic Study.
Anticancer Agents Med Chem
; 18(1): 146-153, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-28745238
17.
Clinical translation of (177)Lu-labeled PSMA-617: Initial experience in prostate cancer patients.
Nucl Med Biol
; 43(5): 296-302, 2016 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-27150032
18.
Formulation of clinical-scale 177Lu-PSMA-617: From laboratory to clinics.
Nucl Med Biol
; 43(12): 836, 2016 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27591896