Detalhe da pesquisa
1.
Ube2v1 Positively Regulates Protein Aggregation by Modulating Ubiquitin Proteasome System Performance Partially Through K63 Ubiquitination.
Circ Res
; 126(7): 907-922, 2020 03 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-32081062
2.
Hypertrophic cardiomyopathy R403Q mutation in rabbit ß-myosin reduces contractile function at the molecular and myofibrillar levels.
Proc Natl Acad Sci U S A
; 115(44): 11238-11243, 2018 10 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-30322937
3.
Myofibroblast-Specific TGFß Receptor II Signaling in the Fibrotic Response to Cardiac Myosin Binding Protein C-Induced Cardiomyopathy.
Circ Res
; 123(12): 1285-1297, 2018 12 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30566042
4.
An Unbiased High-Throughput Screen to Identify Novel Effectors That Impact on Cardiomyocyte Aggregate Levels.
Circ Res
; 121(6): 604-616, 2017 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28655832
5.
Phosphorylation and calcium antagonistically tune myosin-binding protein C's structure and function.
Proc Natl Acad Sci U S A
; 113(12): 3239-44, 2016 Mar 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-26908872
6.
UBC9-Mediated Sumoylation Favorably Impacts Cardiac Function in Compromised Hearts.
Circ Res
; 118(12): 1894-905, 2016 06 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27142163
7.
Circadian rhythms govern cardiac repolarization and arrhythmogenesis.
Nature
; 483(7387): 96-9, 2012 Feb 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-22367544
8.
Myosin-binding protein C displaces tropomyosin to activate cardiac thin filaments and governs their speed by an independent mechanism.
Proc Natl Acad Sci U S A
; 111(6): 2170-5, 2014 Feb 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-24477690
9.
In vivo definition of cardiac myosin-binding protein C's critical interactions with myosin.
Pflugers Arch
; 468(10): 1685-95, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27568194
10.
Sumo E2 enzyme UBC9 is required for efficient protein quality control in cardiomyocytes.
Circ Res
; 115(8): 721-9, 2014 Sep 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-25097219
11.
The protein tyrosine phosphatase Shp2 is required for the generation of oligodendrocyte progenitor cells and myelination in the mouse telencephalon.
J Neurosci
; 34(10): 3767-78, 2014 Mar 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-24599474
12.
An endogenously produced fragment of cardiac myosin-binding protein C is pathogenic and can lead to heart failure.
Circ Res
; 113(5): 553-61, 2013 Aug 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-23852539
13.
Transgenic mouse α- and ß-cardiac myosins containing the R403Q mutation show isoform-dependent transient kinetic differences.
J Biol Chem
; 288(21): 14780-7, 2013 May 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-23580644
14.
Diminished autophagy limits cardiac injury in mouse models of type 1 diabetes.
J Biol Chem
; 288(25): 18077-92, 2013 Jun 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-23658055
15.
Phosphorylation modulates the mechanical stability of the cardiac myosin-binding protein C motif.
Biophys J
; 104(2): 442-52, 2013 Jan 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-23442866
16.
Functional dissection of myosin binding protein C phosphorylation.
J Mol Cell Cardiol
; 64: 39-50, 2013 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-24001940
17.
A critical function for Ser-282 in cardiac Myosin binding protein-C phosphorylation and cardiac function.
Circ Res
; 109(2): 141-50, 2011 Jul 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-21597010
18.
In vivo delivery of nucleic acids via glycopolymer vehicles affords therapeutic infarct size reduction in vivo.
Mol Ther
; 20(3): 601-8, 2012 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-22186793
19.
Determination of the critical residues responsible for cardiac myosin binding protein C's interactions.
J Mol Cell Cardiol
; 53(6): 838-47, 2012 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-22982234
20.
Unique single molecule binding of cardiac myosin binding protein-C to actin and phosphorylation-dependent inhibition of actomyosin motility requires 17 amino acids of the motif domain.
J Mol Cell Cardiol
; 52(1): 219-27, 2012 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-21978630