Detalhe da pesquisa
1.
Autoregulation of Class II Alpha PI3K Activity by Its Lipid-Binding PX-C2 Domain Module.
Mol Cell
; 71(2): 343-351.e4, 2018 07 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-30029007
2.
Lysosomal lipid switch sensitises to nutrient deprivation and mTOR targeting in pancreatic cancer.
Gut
; 72(2): 360-371, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35623884
3.
Mutations in PIK3C2A cause syndromic short stature, skeletal abnormalities, and cataracts associated with ciliary dysfunction.
PLoS Genet
; 15(4): e1008088, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31034465
4.
Spatiotemporal control of endocytosis by phosphatidylinositol-3,4-bisphosphate.
Nature
; 499(7457): 233-7, 2013 Jul 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-23823722
5.
Cytokinetic Abscission: Phosphoinositides and ESCRTs Direct the Final Cut.
J Cell Biochem
; 118(11): 3561-3568, 2017 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-28419521
6.
Phosphoinositide 3-Kinase-C2α Regulates Polycystin-2 Ciliary Entry and Protects against Kidney Cyst Formation.
J Am Soc Nephrol
; 27(4): 1135-44, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26271513
7.
A connection between phosphatidylinositol 5-phosphate and the Hippo pathway to prevent epithelial-mesenchymal transition in cancer.
Sci Signal
; 17(838): eadp3504, 2024 May 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-38805585
8.
Linking phosphoinositide function to mitosis.
Cell Rep
; 43(6): 114273, 2024 Jun 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-38843397
9.
Structural basis of phosphatidylinositol 3-kinase C2α function.
Nat Struct Mol Biol
; 29(3): 218-228, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35256802
10.
Phosphoinositide Conversion Inactivates R-RAS and Drives Metastases in Breast Cancer.
Adv Sci (Weinh)
; 9(9): e2103249, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35098698
11.
Targeting PI3K/AKT/mTOR Signaling Pathway in Breast Cancer.
Cancers (Basel)
; 13(14)2021 Jul 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-34298731
12.
PI(3,4)P2-mediated cytokinetic abscission prevents early senescence and cataract formation.
Science
; 374(6573): eabk0410, 2021 Dec 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34882480
13.
Phosphoinositides in cell proliferation and metabolism.
Adv Biol Regul
; 75: 100693, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32008962
14.
PI(3,4)P2 Signaling in Cancer and Metabolism.
Front Oncol
; 10: 360, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32296634
15.
Targeting PI3K signaling in cancer: Challenges and advances.
Biochim Biophys Acta Rev Cancer
; 1871(2): 361-366, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30946868
16.
Class II PI3K Functions in Cell Biology and Disease.
Trends Cell Biol
; 29(4): 339-359, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30691999
17.
Downregulation of class II phosphoinositide 3-kinase PI3K-C2ß delays cell division and potentiates the effect of docetaxel on cancer cell growth.
J Exp Clin Cancer Res
; 38(1): 472, 2019 Nov 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-31752944
18.
Mitotic Spindle Assembly and Genomic Stability in Breast Cancer Require PI3K-C2α Scaffolding Function.
Cancer Cell
; 32(4): 444-459.e7, 2017 10 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29017056
19.
In Vivo Role of INPP4B in Tumor and Metastasis Suppression through Regulation of PI3K-AKT Signaling at Endosomes.
Cancer Discov
; 5(7): 740-51, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25883022
20.
Methods to measure the enzymatic activity of PI3Ks.
Methods Enzymol
; 543: 115-40, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24924130