Detalhe da pesquisa
1.
Machine learning-driven multiscale modeling reveals lipid-dependent dynamics of RAS signaling proteins.
Proc Natl Acad Sci U S A
; 119(1)2022 01 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34983849
2.
Exploring CRD mobility during RAS/RAF engagement at the membrane.
Biophys J
; 121(19): 3630-3650, 2022 10 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35778842
3.
Optimizing high-yield production of SARS-CoV-2 soluble spike trimers for serology assays.
Protein Expr Purif
; 174: 105686, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32504802
4.
Structural dynamics of RAF1-HSP90-CDC37 and HSP90 complexes reveal asymmetric client interactions and key structural elements.
Commun Biol
; 7(1): 260, 2024 Mar 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38431713
5.
Membrane lipids drive formation of KRAS4b-RAF1 RBDCRD nanoclusters on the membrane.
Commun Biol
; 7(1): 242, 2024 Feb 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-38418613
6.
Mechanism of thioamide drug action against tuberculosis and leprosy.
J Exp Med
; 204(1): 73-8, 2007 Jan 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-17227913
7.
Identification of compounds with potential antibacterial activity against Mycobacterium through structure-based drug screening.
J Chem Inf Model
; 53(5): 1200-12, 2013 May 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-23600706
8.
Machine Learning-Driven Multiscale Modeling: Bridging the Scales with a Next-Generation Simulation Infrastructure.
J Chem Theory Comput
; 19(9): 2658-2675, 2023 May 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37075065
9.
Phosphorylation of InhA inhibits mycolic acid biosynthesis and growth of Mycobacterium tuberculosis.
Mol Microbiol
; 78(6): 1591-605, 2010 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-21143326
10.
Standardization of ELISA protocols for serosurveys of the SARS-CoV-2 pandemic using clinical and at-home blood sampling.
Nat Commun
; 12(1): 113, 2021 01 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33397956
11.
Mycobacterium tuberculosis dihydrofolate reductase is not a target relevant to the antitubercular activity of isoniazid.
Antimicrob Agents Chemother
; 54(9): 3776-82, 2010 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-20566771
12.
Optimizing high-yield production of SARS-CoV-2 soluble spike trimers for serology assays.
bioRxiv
; 2020 May 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-32511418
13.
A Sec14-like phosphatidylinositol transfer protein paralog defines a novel class of heme-binding proteins.
Elife
; 92020 08 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32780017
14.
Standardization of enzyme-linked immunosorbent assays for serosurveys of the SARS-CoV-2 pandemic using clinical and at-home blood sampling.
medRxiv
; 2020 May 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-32511472
15.
Author Correction: Membrane lipids drive formation of KRAS4b-RAF1 RBDCRD nanoclusters on the membrane.
Commun Biol
; 7(1): 445, 2024 Apr 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38605143
16.
Identification of a type III thioesterase reveals the function of an operon crucial for Mtb virulence.
Chem Biol
; 14(5): 543-51, 2007 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-17524985
17.
N-Benzyl-4-((heteroaryl)methyl)benzamides: A New Class of Direct NADH-Dependent 2-trans Enoyl-Acyl Carrier Protein Reductase (InhA) Inhibitors with Antitubercular Activity.
ChemMedChem
; 11(7): 687-701, 2016 Apr 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-26934341
18.
Antitubercular drugs for an old target: GSK693 as a promising InhA direct inhibitor.
EBioMedicine
; 8: 291-301, 2016 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-27428438
19.
Discovery of InhA inhibitors with anti-mycobacterial activity through a matched molecular pair approach.
Eur J Med Chem
; 94: 378-85, 2015 Apr 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-25778993
20.
Structure of the Mtb CarD/RNAP ß-lobes complex reveals the molecular basis of interaction and presents a distinct DNA-binding domain for Mtb CarD.
Structure
; 21(10): 1859-69, 2013 Oct 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-24055315