Detalhe da pesquisa
1.
Clinical Pharmacology and Utility of Contezolid in Chinese Patients with Complicated Skin and Soft-Tissue Infections.
Antimicrob Agents Chemother
; 66(6): e0243021, 2022 06 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-35575579
2.
Polymyxin B Combined with Minocycline: A Potentially Effective Combination against blaOXA-23-harboring CRAB in In Vitro PK/PD Model.
Molecules
; 27(3)2022 Feb 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35164349
3.
Pharmacokinetics and Disposition of Contezolid in Humans: Resolution of a Disproportionate Human Metabolite for Clinical Development.
Antimicrob Agents Chemother
; 65(11): e0040921, 2021 10 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-34398672
4.
Nemonoxacin dosage adjustment in patients with severe renal impairment based on population pharmacokinetic and pharmacodynamic analysis.
Br J Clin Pharmacol
; 87(12): 4636-4647, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33928669
5.
Effects of Different Component Contents of Colistin Methanesulfonate on the Pharmacokinetics of Prodrug and Formed Colistin in Human.
Pharm Res
; 38(1): 79-87, 2021 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-33496870
6.
Evaluation of the Effect of Contezolid (MRX-I) on the Corrected QT Interval in a Randomized, Double-Blind, Placebo- and Positive-Controlled Crossover Study in Healthy Chinese Volunteers.
Antimicrob Agents Chemother
; 64(6)2020 05 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-32229495
7.
Simultaneous separation and determination of vancomycin and its crystalline degradation products in human serum by ultra high performance liquid chromatography tandem mass spectrometry method and its application in therapeutic drug monitoring.
J Sep Sci
; 43(21): 3987-3994, 2020 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-32845063
8.
Pharmacokinetics and pharmacodynamics of multiple-dose intravenous nemonoxacin in healthy Chinese volunteers.
Antimicrob Agents Chemother
; 59(3): 1446-54, 2015 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-25534726
9.
Determination of a novel nonfluorinated quinolone, nemonoxacin, in human feces and its glucuronide conjugate in human urine and feces by high-performance liquid chromatography-triple quadrupole mass spectrometry.
Biomed Chromatogr
; 29(5): 739-48, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25322721
10.
Safety, tolerability, and pharmacokinetics of intravenous nemonoxacin in healthy chinese volunteers.
Antimicrob Agents Chemother
; 58(10): 6116-21, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25092690
11.
Assessment of antimicrobial combinations for Klebsiella pneumoniae carbapenemase-producing K. pneumoniae.
J Infect Dis
; 207(5): 786-93, 2013 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23242537
12.
In vitro pharmacokinetics/pharmacodynamics of FL058 (a novel beta-lactamase inhibitor) combined with meropenem against carbapenemase-producing Enterobacterales.
Front Pharmacol
; 15: 1282480, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38666023
13.
Age-Related Differences in Vancomycin-Associated Nephrotoxicity and Efficacy in Methicillin-Resistant Staphylococcus aureus Infection: A Comparative Study between Elderly and Adult Patients.
Antibiotics (Basel)
; 13(4)2024 Apr 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-38667000
14.
Population pharmacokinetics of levornidazole in healthy subjects and patients, and sequential dosing regimen proposal using pharmacokinetic/pharmacodynamic analysis.
Int J Antimicrob Agents
; 61(4): 106754, 2023 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-36773938
15.
Staphylococcal virulence factor HlgB targets the endoplasmic-reticulum-resident E3 ubiquitin ligase AMFR to promote pneumonia.
Nat Microbiol
; 8(1): 107-120, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36593296
16.
A simple and rapid HPLC-MS/MS method for therapeutic drug monitoring of amikacin in dried matrix spots.
J Chromatogr B Analyt Technol Biomed Life Sci
; 1220: 123592, 2023 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36890098
17.
Safety, Tolerability and Pharmacokinetics of Single and Multiple Doses of Mirogabalin in Healthy Chinese Participants: A Randomized, Double-Blind, Placebo-Controlled Study.
Adv Ther
; 40(4): 1628-1643, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36790683
18.
Integrative population pharmacokinetic/pharmacodynamic analysis of nemonoxacin capsule in Chinese patients with community-acquired pneumonia.
Front Pharmacol
; 14: 912962, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36923351
19.
Population pharmacokinetics and exposure-safety of lipophilic conjugates prodrug DP-VPA in healthy Chinese subjects for dose regime exploring.
Eur J Pharm Biopharm
; 188: 153-160, 2023 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-37142130
20.
Comparative efficacy of vancomycin in treating ST5 and ST764 methicillin-resistant Staphylococcus aureus infections in adult patients.
mSphere
; 8(6): e0045723, 2023 Dec 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-37905831