Primary cancer of the fallopian tubes: histological and immunohistochemical features.

The rare occurrence of the fallopian tubes cancer allows to assert that the experience of even a small number of observations has a undoubted scientific and practical interest. Nowadays this type of neoplasia occurs more o en in practical oncogynecology and is the primary source of serous ovarian and peritoneal tumors. The determination of tissue receptor status of primary fallopian tube cancer (ER, PR, Ki-67, HER2 / neu) will verify the degree of biological malignancy and predict the course of disease and suggest appropriate methods of treatment.

The features of morphological changes in the urinary bladder under combined effect of heavy metal salts.

PURPOSE: This study is aimed to the investigation of the features of morphological changes in the urinary bladder of mature rats. RESULTS: Received results shown that the experimental group of rats that had the intake of heavy metal salts (HMS) mixture during 30 and 90 days were observed histological and immunohistochemical changes in all structures of the urinary bladder. Depending on the period of influence of heavy metal ions on the wall of the organ, the pathological changes developed in cellular layers of the wall can lead to degenerative and later to atrophic and sclerotic changes. CONCLUSIONS: This study demonstrates that high concentrations of HMS can significantly influence the body. The histological and immunohistochemical studies showed that the influence of the HMS combination leads to deep morphological changes in all structures of the urinary bladder. These changes depend on the period of intake of HMS. Analysis of the obtained results demonstrates the dependence of expression of morphological changes in the urinary bladder on the experiment duration. The final result of these changes may lead to the disorders of bladder's functions.

A rare case of tuberculous salpingitis.

The objective of this study was to give an overview of a rare case of tuberculosis of the left fallopian tube in postmenopausal women. It is known that the isolated tuberculous salpingitis without spreading to the endometrium is extremely rare case. In our case, it simulated a cancer of appendages at the late stages that were proved by the increased level of CA-125. This fact as well as the macroscopic image of the left fallopian tube was incorrectly considered by the clinicians as a malignant neoplasm of fallopian tube. However, after pathomorphological examination of postoperative samples during histological study, the main method of verification of the diagnosis, revealed the specific granulomas in the samples that indicate the tubercular inflammation. It was considered by clinical and laboratory as data secondary focus.