Detalhe da pesquisa
1.
Determining recommended acceptable intake limits for N-nitrosamine impurities in pharmaceuticals: Development and application of the Carcinogenic Potency Categorization Approach (CPCA).
Regul Toxicol Pharmacol
; 150: 105640, 2024 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-38754805
2.
A comprehensive view on mechanistic approaches for cancer risk assessment of non-genotoxic agrochemicals.
Regul Toxicol Pharmacol
; 118: 104789, 2020 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-33035627
3.
Cytotoxic and Senolytic Effects of Methadone in Combination with Temozolomide in Glioblastoma Cells.
Int J Mol Sci
; 21(19)2020 Sep 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-32977591
4.
Inhibition of the PI3K but not the MEK/ERK pathway sensitizes human glioma cells to alkylating drugs.
Cancer Cell Int
; 18: 69, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29755294
5.
Thioredoxin Confers Intrinsic Resistance to Cytostatic Drugs in Human Glioma Cells.
Int J Mol Sci
; 19(10)2018 Sep 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-30248944
6.
Is sunitinib a Narrow Therapeutic Index Drug? - A systematic review and in vitro toxicology-analysis of Sunitinib vs. Imatinib in cells from different tissues.
Regul Toxicol Pharmacol
; 77: 25-34, 2016 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-26924275
7.
Increased cGMP promotes healthy expansion and browning of white adipose tissue.
FASEB J
; 27(4): 1621-30, 2013 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-23303211
8.
Clinical pharmacology and regulatory consequences of GnRH analogues in prostate cancer.
Eur J Clin Pharmacol
; 70(7): 791-8, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24756149
9.
Sulfonylureas exert antidiabetic action on adipocytes by inhibition of PPARγ serine 273 phosphorylation.
Mol Metab
; 85: 101956, 2024 May 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-38735390
10.
Neurotensin(8-13) analogs as dual NTS1 and NTS2 receptor ligands with enhanced effects on a mouse model of Parkinson's disease.
Eur J Med Chem
; 254: 115386, 2023 Jun 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37094450
11.
Methadone-mediated sensitization of glioblastoma cells is drug and cell line dependent.
J Cancer Res Clin Oncol
; 147(3): 779-792, 2021 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-33315125
12.
A novel crosstalk between Alk7 and cGMP signaling differentially regulates brown adipocyte function.
Mol Metab
; 4(8): 576-83, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-26266090
13.
Systemic therapy of Cushing's syndrome.
Orphanet J Rare Dis
; 9: 122, 2014 Aug 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-25091295
14.
Clinical pharmacology of tyrosine kinase inhibitors becoming generic drugs: the regulatory perspective.
J Exp Clin Cancer Res
; 33: 15, 2014 Feb 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-24502453
15.
miR-155 regulates differentiation of brown and beige adipocytes via a bistable circuit.
Nat Commun
; 4: 1769, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23612310
16.
Analysis of cGMP signaling in adipocytes.
Methods Mol Biol
; 1020: 175-92, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23709033
17.
Targeting adipose tissue.
Diabetol Metab Syndr
; 4(1): 43, 2012 Oct 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-23102228
18.
Cyclic GMP and protein kinase G control a Src-containing mechanosome in osteoblasts.
Sci Signal
; 3(153): ra91, 2010 Dec 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-21177494
19.
Protein kinase G controls brown fat cell differentiation and mitochondrial biogenesis.
Sci Signal
; 2(99): ra78, 2009 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19952371
20.
Down-regulation of CYLD expression by Snail promotes tumor progression in malignant melanoma.
J Exp Med
; 206(1): 221-32, 2009 Jan 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-19124656