Detalhe da pesquisa
1.
Phase 3, multicentre, randomised, placebo-controlled study evaluating the efficacy and safety of ustekinumab in patients with systemic lupus erythematosus.
Ann Rheum Dis
; 2022 Jul 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35798534
2.
Loss-of-function variants in SAT1 cause X-linked childhood-onset systemic lupus erythematosus.
Ann Rheum Dis
; 81(12): 1712-1721, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35977808
3.
Efficacy and safety of ustekinumab, an IL-12 and IL-23 inhibitor, in patients with active systemic lupus erythematosus: results of a multicentre, double-blind, phase 2, randomised, controlled study.
Lancet
; 392(10155): 1330-1339, 2018 10 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-30249507
4.
Decreased SMG7 expression associates with lupus-risk variants and elevated antinuclear antibody production.
Ann Rheum Dis
; 75(11): 2007-2013, 2016 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26783109
5.
MicroRNA-3148 modulates allelic expression of toll-like receptor 7 variant associated with systemic lupus erythematosus.
PLoS Genet
; 9(2): e1003336, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23468661
6.
Preferential binding to Elk-1 by SLE-associated IL10 risk allele upregulates IL10 expression.
PLoS Genet
; 9(10): e1003870, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-24130510
7.
Paraoxonase-3 is depleted from the high-density lipoproteins of autoimmune disease patients with subclinical atherosclerosis.
J Proteome Res
; 14(5): 2046-54, 2015 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25723336
8.
Genetic associations of leptin-related polymorphisms with systemic lupus erythematosus.
Clin Immunol
; 161(2): 157-62, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26385092
9.
Blockade of programmed death-1 in young (New Zealand Black x New Zealand White)F1 mice promotes the suppressive capacity of CD4+ regulatory T cells protecting from lupus-like disease.
J Immunol
; 190(11): 5402-10, 2013 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23636058
10.
Association of genetic variants in complement factor H and factor H-related genes with systemic lupus erythematosus susceptibility.
PLoS Genet
; 7(5): e1002079, 2011 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-21637784
11.
Fine mapping of Xq28: both MECP2 and IRAK1 contribute to risk for systemic lupus erythematosus in multiple ancestral groups.
Ann Rheum Dis
; 72(3): 437-44, 2013 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-22904263
12.
Sex-specific association of X-linked Toll-like receptor 7 (TLR7) with male systemic lupus erythematosus.
Proc Natl Acad Sci U S A
; 107(36): 15838-43, 2010 Sep 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-20733074
13.
Tolerance induced by anti-DNA Ig peptide in (NZB×NZW)F1 lupus mice impinges on the resistance of effector T cells to suppression by regulatory T cells.
Clin Immunol
; 142(3): 291-5, 2012 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-22137928
14.
Association of a functional IRF7 variant with systemic lupus erythematosus.
Arthritis Rheum
; 63(3): 749-54, 2011 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-21360504
15.
Association of PPP2CA polymorphisms with systemic lupus erythematosus susceptibility in multiple ethnic groups.
Arthritis Rheum
; 63(9): 2755-63, 2011 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-21590681
16.
Blockade of programmed death-1 in young (New Zealand black x New Zealand white)F1 mice promotes the activity of suppressive CD8+ T cells that protect from lupus-like disease.
J Immunol
; 185(11): 6563-71, 2010 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21041733
17.
Identification and Contribution of Inflammation-Induced Novel MicroRNA in the Pathogenesis of Systemic Lupus Erythematosus.
Front Immunol
; 13: 848149, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35444657
18.
Efficacy and Safety of Ustekinumab in Patients With Active Systemic Lupus Erythematosus: Results of a Phase II Open-label Extension Study.
J Rheumatol
; 49(4): 380-387, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34853089
19.
Targeted therapies in systemic lupus erythematosus: successes, failures and future.
Ann Rheum Dis
; 70 Suppl 1: i64-i66, 2011 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-21339222
20.
High plasma leptin levels confer increased risk of atherosclerosis in women with systemic lupus erythematosus, and are associated with inflammatory oxidised lipids.
Ann Rheum Dis
; 70(9): 1619-24, 2011 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-21670088