Detalhe da pesquisa
1.
Signalling of Adrenoceptors: Canonical Pathways and New Paradigms.
Handb Exp Pharmacol
; 2024 Jan 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-38227198
2.
Endosomal signaling of delta opioid receptors is an endogenous mechanism and therapeutic target for relief from inflammatory pain.
Proc Natl Acad Sci U S A
; 117(26): 15281-15292, 2020 06 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-32546520
3.
A lipid-anchored neurokinin 1 receptor antagonist prolongs pain relief by a three-pronged mechanism of action targeting the receptor at the plasma membrane and in endosomes.
J Biol Chem
; 296: 100345, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33515548
4.
Protease-activated receptor-2 in endosomes signals persistent pain of irritable bowel syndrome.
Proc Natl Acad Sci U S A
; 115(31): E7438-E7447, 2018 07 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-30012612
5.
Ligand-dependent spatiotemporal signaling profiles of the µ-opioid receptor are controlled by distinct protein-interaction networks.
J Biol Chem
; 294(44): 16198-16213, 2019 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31515267
6.
A ligand-induced structural change in fatty acid-binding protein 1 is associated with potentiation of peroxisome proliferator-activated receptor α agonists.
J Biol Chem
; 294(10): 3720-3734, 2019 03 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30598509
7.
Endosomal signaling of the receptor for calcitonin gene-related peptide mediates pain transmission.
Proc Natl Acad Sci U S A
; 114(46): 12309-12314, 2017 11 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-29087309
8.
International Union of Basic and Clinical Pharmacology. XCV. Recent advances in the understanding of the pharmacology and biological roles of relaxin family peptide receptors 1-4, the receptors for relaxin family peptides.
Pharmacol Rev
; 67(2): 389-440, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25761609
9.
The ß2-adrenoceptor activates a positive cAMP-calcium feedforward loop to drive breast cancer cell invasion.
FASEB J
; 30(3): 1144-54, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-26578688
10.
The Phosphatidylinositol (3,4,5)-Trisphosphate-dependent Rac Exchanger 1·Ras-related C3 Botulinum Toxin Substrate 1 (P-Rex1·Rac1) Complex Reveals the Basis of Rac1 Activation in Breast Cancer Cells.
J Biol Chem
; 290(34): 20827-20840, 2015 Aug 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-26112412
11.
Fatty Acid-binding Proteins 1 and 2 Differentially Modulate the Activation of Peroxisome Proliferator-activated Receptor α in a Ligand-selective Manner.
J Biol Chem
; 290(22): 13895-906, 2015 May 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-25847235
12.
Compartmentalization of GPCR signalling controls unique cellular responses.
Biochem Soc Trans
; 44(2): 562-7, 2016 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27068970
13.
The complexity of signalling mediated by the glucagon-like peptide-1 receptor.
Biochem Soc Trans
; 44(2): 582-8, 2016 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27068973
14.
ß2-Adrenoceptors on tumor cells play a critical role in stress-enhanced metastasis in a mouse model of breast cancer.
Brain Behav Immun
; 57: 106-115, 2016 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-27321906
15.
Macromolecular Hydrogen Sulfide Donors Trigger Spatiotemporally Confined Changes in Cell Signaling.
Biomacromolecules
; 17(1): 371-83, 2016 Jan 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-26653086
16.
Endothelin-converting enzyme 1 and ß-arrestins exert spatiotemporal control of substance P-induced inflammatory signals.
J Biol Chem
; 289(29): 20283-94, 2014 Jul 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-24898255
17.
ß2-adrenoceptor signaling regulates invadopodia formation to enhance tumor cell invasion.
Breast Cancer Res
; 17(1): 145, 2015 Nov 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-26607426
18.
Sub-picomolar relaxin signalling by a pre-assembled RXFP1, AKAP79, AC2, beta-arrestin 2, PDE4D3 complex.
EMBO J
; 29(16): 2772-87, 2010 Aug 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-20664520
19.
A key phosphorylation site in AC8 mediates regulation of Ca(2+)-dependent cAMP dynamics by an AC8-AKAP79-PKA signalling complex.
J Cell Sci
; 125(Pt 23): 5850-9, 2012 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22976297
20.
Adenylyl cyclase AC8 directly controls its micro-environment by recruiting the actin cytoskeleton in a cholesterol-rich milieu.
J Cell Sci
; 125(Pt 4): 869-86, 2012 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22399809