Detalhe da pesquisa
1.
Parenchymal border macrophages regulate the flow dynamics of the cerebrospinal fluid.
Nature
; 611(7936): 585-593, 2022 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-36352225
2.
Brain high-throughput multi-omics data reveal molecular heterogeneity in Alzheimer's disease.
PLoS Biol
; 22(4): e3002607, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38687811
3.
Meningeal lymphatics affect microglia responses and anti-Aß immunotherapy.
Nature
; 593(7858): 255-260, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33911285
4.
Preclinical Alzheimer's disease biomarkers accurately predict cognitive and neuropathological outcomes.
Brain
; 145(12): 4506-4518, 2022 12 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-35867858
5.
Multi-ancestry GWAS reveals excitotoxicity associated with outcome after ischaemic stroke.
Brain
; 145(7): 2394-2406, 2022 07 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-35213696
6.
Metabolomic and lipidomic signatures in autosomal dominant and late-onset Alzheimer's disease brains.
Alzheimers Dement
; 19(5): 1785-1799, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36251323
7.
Alzheimer's disease alters oligodendrocytic glycolytic and ketolytic gene expression.
Alzheimers Dement
; 17(9): 1474-1486, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33650792
8.
Overlapping genetic architecture between Parkinson disease and melanoma.
Acta Neuropathol
; 139(2): 347-364, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31845298
9.
Correction to: Overlapping genetic architecture between Parkinson disease and melanoma.
Acta Neuropathol
; 139(5): 963, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32172342
10.
TREM2 activation on microglia promotes myelin debris clearance and remyelination in a model of multiple sclerosis.
Acta Neuropathol
; 140(4): 513-534, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32772264
11.
The TMEM106B FTLD-protective variant, rs1990621, is also associated with increased neuronal proportion.
Acta Neuropathol
; 139(1): 45-61, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31456032
12.
Rare coding variants in the phospholipase D3 gene confer risk for Alzheimer's disease.
Nature
; 505(7484): 550-554, 2014 Jan 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-24336208
13.
Analysis of neurodegenerative Mendelian genes in clinically diagnosed Alzheimer Disease.
PLoS Genet
; 13(11): e1007045, 2017 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-29091718
14.
Polygenic risk score of sporadic late-onset Alzheimer's disease reveals a shared architecture with the familial and early-onset forms.
Alzheimers Dement
; 14(2): 205-214, 2018 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28943286
15.
Genome-wide association study identifies four novel loci associated with Alzheimer's endophenotypes and disease modifiers.
Acta Neuropathol
; 133(5): 839-856, 2017 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28247064
16.
Parkinson disease polygenic risk score is associated with Parkinson disease status and age at onset but not with alpha-synuclein cerebrospinal fluid levels.
BMC Neurol
; 17(1): 198, 2017 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29141588
17.
Genome-wide association study of CSF levels of 59 alzheimer's disease candidate proteins: significant associations with proteins involved in amyloid processing and inflammation.
PLoS Genet
; 10(10): e1004758, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25340798
18.
Coding variants in TREM2 increase risk for Alzheimer's disease.
Hum Mol Genet
; 23(21): 5838-46, 2014 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24899047
19.
Use of a predictive model derived from in vivo endophenotype measurements to demonstrate associations with a complex locus, CYP2A6.
Hum Mol Genet
; 21(13): 3050-62, 2012 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22451501
20.
Comparative gene regulatory networks modulating APOE expression in microglia and astrocytes.
medRxiv
; 2024 Apr 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-38699303