Detalhe da pesquisa
1.
Tafenoquine versus Primaquine to Prevent Relapse of Plasmodium vivax Malaria.
N Engl J Med
; 380(3): 229-241, 2019 01 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-30650326
2.
Single-Dose Tafenoquine to Prevent Relapse of Plasmodium vivax Malaria.
N Engl J Med
; 380(3): 215-228, 2019 01 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-30650322
3.
Development of autotaxin inhibitors: A series of tetrazole cinnamides.
Bioorg Med Chem Lett
; 31: 127663, 2021 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33160025
4.
Development of autotaxin inhibitors: A series of zinc binding triazoles.
Bioorg Med Chem Lett
; 28(13): 2279-2284, 2018 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29798825
5.
Efficacy and pharmacodynamic effect of anti-CD73 and anti-PD-L1 monoclonal antibodies in combination with cytotoxic therapy: observations from mouse tumor models.
Cancer Biol Ther
; 25(1): 2296048, 2024 12 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-38206570
6.
The ATR inhibitor ceralasertib potentiates cancer checkpoint immunotherapy by regulating the tumor microenvironment.
Nat Commun
; 15(1): 1700, 2024 Feb 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-38402224
7.
Generating Selective Leads for Mer Kinase Inhibitors-Example of a Comprehensive Lead-Generation Strategy.
J Med Chem
; 64(6): 3165-3184, 2021 03 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-33683117
8.
Optimization of an Imidazo[1,2-a]pyridine Series to Afford Highly Selective Type I1/2 Dual Mer/Axl Kinase Inhibitors with In Vivo Efficacy.
J Med Chem
; 64(18): 13524-13539, 2021 09 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-34478292
9.
Liver X receptor agonists increase airway reactivity in a model of asthma via increasing airway smooth muscle growth.
J Immunol
; 181(6): 4265-71, 2008 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18768884
10.
A multi-batch design to deliver robust estimates of efficacy and reduce animal use - a syngeneic tumour case study.
Sci Rep
; 10(1): 6178, 2020 04 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32277094
11.
Development of an ObLiGaRe Doxycycline Inducible Cas9 system for pre-clinical cancer drug discovery.
Nat Commun
; 11(1): 4903, 2020 09 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-32994412
12.
Longitudinal immune characterization of syngeneic tumor models to enable model selection for immune oncology drug discovery.
J Immunother Cancer
; 7(1): 328, 2019 11 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-31779705
13.
Randomized Placebo-Controlled Trial Evaluating the Ophthalmic Safety of Single-Dose Tafenoquine in Healthy Volunteers.
Drug Saf
; 42(9): 1103-1114, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31187437
14.
Estrogen receptor beta: expression profile and possible anti-inflammatory role in disease.
J Pharmacol Exp Ther
; 326(1): 83-8, 2008 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-18375789
15.
Functional significance of co-occurring mutations in PIK3CA and MAP3K1 in breast cancer.
Oncotarget
; 9(30): 21444-21458, 2018 Apr 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-29765551
16.
PI3Kα/δ inhibition promotes anti-tumor immunity through direct enhancement of effector CD8+ T-cell activity.
J Immunother Cancer
; 6(1): 158, 2018 12 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-30587236
17.
Characterisation of lung macrophage subpopulations in COPD patients and controls.
Sci Rep
; 7(1): 7143, 2017 08 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28769058
18.
Regulation of TNF-alpha- and IFN-gamma-induced CXCL10 expression: participation of the airway smooth muscle in the pulmonary inflammatory response in chronic obstructive pulmonary disease.
FASEB J
; 18(1): 191-3, 2004 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-14597565
19.
Novel role for the liver X nuclear receptor in the suppression of lung inflammatory responses.
J Biol Chem
; 282(44): 31882-90, 2007 Nov 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-17766241
20.
Second-generation inhibitors demonstrate the involvement of p38 mitogen-activated protein kinase in post-transcriptional modulation of inflammatory mediator production in human and rodent airways.
J Pharmacol Exp Ther
; 316(3): 1318-27, 2006 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-16368902