Detalhe da pesquisa
1.
Antisense Oligonucleotides Targeting Jagged 1 Reduce House Dust Mite-induced Goblet Cell Metaplasia in the Adult Murine Lung.
Am J Respir Cell Mol Biol
; 63(1): 46-56, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32176858
2.
A modular analysis of microglia gene expression, insights into the aged phenotype.
BMC Genomics
; 20(1): 164, 2019 Feb 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-30819113
3.
Viable RNaseH1 knockout mice show RNaseH1 is essential for R loop processing, mitochondrial and liver function.
Nucleic Acids Res
; 44(11): 5299-312, 2016 06 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-27131367
4.
Hepatotoxicity of high affinity gapmer antisense oligonucleotides is mediated by RNase H1 dependent promiscuous reduction of very long pre-mRNA transcripts.
Nucleic Acids Res
; 44(5): 2093-109, 2016 Mar 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-26553810
5.
Integrated Safety Assessment of 2'-O-Methoxyethyl Chimeric Antisense Oligonucleotides in NonHuman Primates and Healthy Human Volunteers.
Mol Ther
; 24(10): 1771-1782, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27357629
6.
Synthesis, biophysical properties and biological activity of second generation antisense oligonucleotides containing chiral phosphorothioate linkages.
Nucleic Acids Res
; 42(22): 13456-68, 2014 Dec 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-25398895
7.
Transfection of siRNAs can alter miRNA levels and trigger non-specific protein degradation in mammalian cells.
Biochim Biophys Acta
; 1829(5): 455-68, 2013 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-23403288
8.
A novel 'social contract' - An attempt to harmonize a sponsor's exploratory research with a clinical study participant's data rights.
Contemp Clin Trials
; 119: 106819, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35691489
9.
Antisense oligonucleotide treatment ameliorates IFN-γ-induced proteinuria in APOL1-transgenic mice.
JCI Insight
; 4(12)2019 06 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-31217349
10.
Chemical modification of PS-ASO therapeutics reduces cellular protein-binding and improves the therapeutic index.
Nat Biotechnol
; 37(6): 640-650, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31036929
11.
Connectivity in the yeast cell cycle transcription network: inferences from neural networks.
PLoS Comput Biol
; 2(12): e169, 2006 Dec 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-17194216
12.
A mathematical and computational framework for quantitative comparison and integration of large-scale gene expression data.
Nucleic Acids Res
; 33(8): 2580-94, 2005.
Artigo
em Inglês
| MEDLINE | ID: mdl-15886390
13.
Mining gene expression data by interpreting principal components.
BMC Bioinformatics
; 7: 194, 2006 Apr 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-16600052
14.
Partial Hepatectomy Induced Long Noncoding RNA Inhibits Hepatocyte Proliferation during Liver Regeneration.
PLoS One
; 10(7): e0132798, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26207833
15.
Helicos single-molecule sequencing of bacterial genomes.
Methods Mol Biol
; 733: 3-24, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-21431759