Detalhe da pesquisa
1.
Inborn Errors of RNA Lariat Metabolism in Humans with Brainstem Viral Infection.
Cell
; 172(5): 952-965.e18, 2018 02 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-29474921
2.
Activation of human RNA lariat debranching enzyme Dbr1 by binding protein TTDN1 occurs though an intrinsically disordered C-terminal domain.
J Biol Chem
; 299(9): 105100, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37507019
3.
Crystal Structure of the RNA Lariat Debranching Enzyme Dbr1 with Hydrolyzed Phosphorothioate RNA Product.
Biochemistry
; 61(24): 2933-2939, 2022 12 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-36484984
4.
A pH Switch Controls Zinc Binding in Tomato Copper-Zinc Superoxide Dismutase.
Biochemistry
; 60(20): 1597-1608, 2021 05 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-33961402
5.
Oxamniquine resistance alleles are widespread in Old World Schistosoma mansoni and predate drug deployment.
PLoS Pathog
; 15(10): e1007881, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31652296
6.
Localized Induction of Wild-Type and Mutant Alpha-Synuclein Aggregation Reveals Propagation along Neuroanatomical Tracts.
J Virol
; 92(18)2018 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29976670
7.
Metal dependence and branched RNA cocrystal structures of the RNA lariat debranching enzyme Dbr1.
Proc Natl Acad Sci U S A
; 113(51): 14727-14732, 2016 12 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-27930312
8.
Copper-zinc superoxide dismutase is activated through a sulfenic acid intermediate at a copper ion entry site.
J Biol Chem
; 292(29): 12025-12040, 2017 07 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-28533431
9.
Structural and enzymatic insights into species-specific resistance to schistosome parasite drug therapy.
J Biol Chem
; 292(27): 11154-11164, 2017 07 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28536265
10.
An engineered transforming growth factor ß (TGF-ß) monomer that functions as a dominant negative to block TGF-ß signaling.
J Biol Chem
; 292(17): 7173-7188, 2017 04 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-28228478
11.
Structure of CARDS toxin, a unique ADP-ribosylating and vacuolating cytotoxin from Mycoplasma pneumoniae.
Proc Natl Acad Sci U S A
; 112(16): 5165-70, 2015 Apr 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-25848012
12.
Non-Native Metal Ion Reveals the Role of Electrostatics in Synaptotagmin 1-Membrane Interactions.
Biochemistry
; 56(25): 3283-3295, 2017 06 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-28574251
13.
The Phylogeny and Active Site Design of Eukaryotic Copper-only Superoxide Dismutases.
J Biol Chem
; 291(40): 20911-20923, 2016 Sep 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-27535222
14.
Potassium and the K+/H+ Exchanger Kha1p Promote Binding of Copper to ApoFet3p Multi-copper Ferroxidase.
J Biol Chem
; 291(18): 9796-806, 2016 Apr 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-26966178
15.
Aggregation-triggering segments of SOD1 fibril formation support a common pathway for familial and sporadic ALS.
Proc Natl Acad Sci U S A
; 111(1): 197-201, 2014 Jan 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-24344300
16.
Candida albicans SOD5 represents the prototype of an unprecedented class of Cu-only superoxide dismutases required for pathogen defense.
Proc Natl Acad Sci U S A
; 111(16): 5866-71, 2014 Apr 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-24711423
17.
Insights into the role of the unusual disulfide bond in copper-zinc superoxide dismutase.
J Biol Chem
; 290(4): 2405-18, 2015 Jan 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-25433341
18.
Distinct conformers of transmissible misfolded SOD1 distinguish human SOD1-FALS from other forms of familial and sporadic ALS.
Acta Neuropathol
; 132(6): 827-840, 2016 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27704280
19.
Structure of the Hsp110:Hsc70 nucleotide exchange machine.
Mol Cell
; 31(2): 232-43, 2008 Jul 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-18550409
20.
Structural basis of lariat RNA recognition by the intron debranching enzyme Dbr1.
Nucleic Acids Res
; 42(16): 10845-55, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25123664