Detalhe da pesquisa
1.
NPP-669, a Novel Broad-Spectrum Antiviral Therapeutic with Excellent Cellular Uptake, Antiviral Potency, Oral Bioavailability, Preclinical Efficacy, and a Promising Safety Margin.
Mol Pharm
; 20(1): 370-382, 2023 01 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36484496
2.
Xenotransplantation panel for the detection of infectious agents in pigs.
Xenotransplantation
; 25(4): e12427, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30264882
3.
Dihydropyrimidinones and -thiones with improved activity against human polyomavirus family members.
Bioorg Med Chem Lett
; 26(20): 5087-5091, 2016 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27624078
4.
Human cytomegalovirus UL97 kinase is involved in the mechanism of action of methylenecyclopropane analogs with 6-ether and -thioether substitutions.
Antimicrob Agents Chemother
; 58(1): 274-8, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24145545
5.
Selection and recombinant phenotyping of a novel CMX001 and cidofovir resistance mutation in human cytomegalovirus.
Antimicrob Agents Chemother
; 57(7): 3321-5, 2013 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-23650158
6.
Synthesis and antiviral activities of methylenecyclopropane analogs with 6-alkoxy and 6-alkylthio substitutions that exhibit broad-spectrum antiviral activity against human herpesviruses.
Antimicrob Agents Chemother
; 57(8): 3518-27, 2013 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-23669381
7.
In Silico Design and Experimental Validation of Novel Oxazole Derivatives Against Varicella zoster virus.
Mol Biotechnol
; 2023 Jan 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-36709460
8.
Synthesis and antiviral activity of certain second generation methylenecyclopropane nucleosides.
Bioorg Med Chem
; 20(12): 3710-8, 2012 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22607883
9.
CMX001 potentiates the efficacy of acyclovir in herpes simplex virus infections.
Antimicrob Agents Chemother
; 55(10): 4728-34, 2011 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-21788472
10.
Cyclopropavir inhibits the normal function of the human cytomegalovirus UL97 kinase.
Antimicrob Agents Chemother
; 55(10): 4682-91, 2011 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-21788463
11.
Inhibition of herpesvirus replication by 5-substituted 4'-thiopyrimidine nucleosides.
Antimicrob Agents Chemother
; 53(12): 5251-8, 2009 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-19770274
12.
Human cytomegalovirus UL97 kinase activity is required for the hyperphosphorylation of retinoblastoma protein and inhibits the formation of nuclear aggresomes.
J Virol
; 82(10): 5054-67, 2008 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-18321963
13.
Conserved retinoblastoma protein-binding motif in human cytomegalovirus UL97 kinase minimally impacts viral replication but affects susceptibility to maribavir.
Virol J
; 6: 9, 2009 Jan 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-19159461
14.
Inhibition of herpesvirus replication by hexadecyloxypropyl esters of purine- and pyrimidine-based phosphonomethoxyethyl nucleoside phosphonates.
Antimicrob Agents Chemother
; 52(12): 4326-30, 2008 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-18852272
15.
Effect of oral treatment with (S)-HPMPA, HDP-(S)-HPMPA or ODE-(S)-HPMPA on replication of murine cytomegalovirus (MCMV) or human cytomegalovirus (HCMV) in animal models.
Antiviral Res
; 79(2): 133-5, 2008 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-18336926
16.
A standardized approach to the evaluation of antivirals against DNA viruses: Polyomaviruses and lymphotropic herpesviruses.
Antiviral Res
; 159: 122-129, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30287227
17.
A standardized approach to the evaluation of antivirals against DNA viruses: Orthopox-, adeno-, and herpesviruses.
Antiviral Res
; 159: 104-112, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30287226
18.
USC-087 protects Syrian hamsters against lethal challenge with human species C adenoviruses.
Antiviral Res
; 153: 1-9, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29510156
19.
Synthesis and antiviral evaluation of alkoxyalkyl-phosphate conjugates of cidofovir and adefovir.
Antiviral Res
; 75(1): 87-90, 2007 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-17367874
20.
Synthesis and antiviral evaluation of alkoxyalkyl esters of phosphonopropoxymethyl-guanine and phosphonopropoxymethyl-diaminopurine.
Antivir Chem Chemother
; 17(2): 89-95, 2006.
Artigo
em Inglês
| MEDLINE | ID: mdl-17042330