Detalhe da pesquisa
1.
Highly active CAR T cells that bind to a juxtamembrane region of mesothelin and are not blocked by shed mesothelin.
Proc Natl Acad Sci U S A
; 119(19): e2202439119, 2022 05 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35512094
2.
NAV-003, a bispecific antibody targeting a unique mesothelin epitope and CD3ε with improved cytotoxicity against humoral immunosuppressed tumors.
Eur J Immunol
; 53(8): e2250309, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37146241
3.
Heterozygous germline BLM mutations increase susceptibility to asbestos and mesothelioma.
Proc Natl Acad Sci U S A
; 117(52): 33466-33473, 2020 12 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-33318203
4.
Anetumab ravtansine versus vinorelbine in patients with relapsed, mesothelin-positive malignant pleural mesothelioma (ARCS-M): a randomised, open-label phase 2 trial.
Lancet Oncol
; 23(4): 540-552, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35358455
5.
Inherited predisposition to malignant mesothelioma and overall survival following platinum chemotherapy.
Proc Natl Acad Sci U S A
; 116(18): 9008-9013, 2019 04 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-30975761
6.
Malignant mesothelioma: Advances in immune checkpoint inhibitor and mesothelin-targeted therapies.
Cancer
; 127(7): 1010-1020, 2021 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33620732
7.
CD70 expression correlates with a worse prognosis in malignant pleural mesothelioma patients via immune evasion and enhanced invasiveness.
J Pathol
; 250(2): 205-216, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31639216
8.
Phase 1 study of the immunotoxin LMB-100 in patients with mesothelioma and other solid tumors expressing mesothelin.
Cancer
; 126(22): 4936-4947, 2020 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32870522
9.
Workshop summary: Potential usefulness and feasibility of a US National Mesothelioma Registry.
Am J Ind Med
; 63(2): 105-114, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31743489
10.
Recombinant immunotoxin for cancer treatment with low immunogenicity by identification and silencing of human T-cell epitopes.
Proc Natl Acad Sci U S A
; 111(23): 8571-6, 2014 Jun 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-24799704
11.
Antibody-drug conjugates for cancer therapy.
Lancet Oncol
; 17(6): e254-e262, 2016 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27299281
12.
Orbital metastases from malignant mesothelioma.
Lancet Oncol
; 21(2): e117, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32007197
13.
Advances in anticancer immunotoxin therapy.
Oncologist
; 20(2): 176-85, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25561510
14.
A Listeria vaccine and depletion of T-regulatory cells activate immunity against early stage pancreatic intraepithelial neoplasms and prolong survival of mice.
Gastroenterology
; 146(7): 1784-94.e6, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24607504
15.
Mesothelioma patient derived tumor xenografts with defined BAP1 mutations that mimic the molecular characteristics of human malignant mesothelioma.
BMC Cancer
; 15: 376, 2015 May 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-25952750
16.
Immunotoxin therapy of cancer.
Nat Rev Cancer
; 6(7): 559-65, 2006 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-16794638
17.
Recombinant immunotoxin engineered for low immunogenicity and antigenicity by identifying and silencing human B-cell epitopes.
Proc Natl Acad Sci U S A
; 109(29): 11782-7, 2012 Jul 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-22753489
18.
Phase 1 study of the antimesothelin immunotoxin SS1P in combination with pemetrexed and cisplatin for front-line therapy of pleural mesothelioma and correlation of tumor response with serum mesothelin, megakaryocyte potentiating factor, and cancer antigen 125.
Cancer
; 120(21): 3311-9, 2014 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24989332
19.
Pre-existing antiacetylcholine receptor autoantibodies and B cell lymphopaenia are associated with the development of myositis in patients with thymoma treated with avelumab, an immune checkpoint inhibitor targeting programmed death-ligand 1.
Ann Rheum Dis
; 78(1): 150-152, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30185415
20.
New insights into understanding the mechanisms, pathogenesis, and management of malignant mesotheliomas.
Am J Pathol
; 182(4): 1065-77, 2013 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-23395095