Detalhe da pesquisa
1.
Cell-Autonomous versus Systemic Akt Isoform Deletions Uncovered New Roles for Akt1 and Akt2 in Breast Cancer.
Mol Cell
; 80(1): 87-101.e5, 2020 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32931746
2.
Quantitative Lipid Imaging Reveals a New Signaling Function of Phosphatidylinositol-3,4-Bisphophate: Isoform- and Site-Specific Activation of Akt.
Mol Cell
; 71(6): 1092-1104.e5, 2018 09 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-30174291
3.
Microfluidic isolation of breast cancer circulating tumor cells from microvolumes of mouse blood.
Electrophoresis
; 44(23): 1859-1867, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37528726
4.
FGF-dependent metabolic control of vascular development.
Nature
; 545(7653): 224-228, 2017 05 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-28467822
5.
Amalgam regulates the receptor tyrosine kinase pathway through Sprouty in glial cell development in the Drosophila larval brain.
J Cell Sci
; 133(19)2020 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32878945
6.
Hijacking leucyl-tRNA synthetase for amino acid-dependent regulation of TORC1.
Mol Cell
; 46(1): 4-6, 2012 Apr 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-22500735
7.
Akt2 (Protein Kinase B Beta) Stabilizes ATP7A, a Copper Transporter for Extracellular Superoxide Dismutase, in Vascular Smooth Muscle: Novel Mechanism to Limit Endothelial Dysfunction in Type 2 Diabetes Mellitus.
Arterioscler Thromb Vasc Biol
; 38(3): 529-541, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29301787
8.
The pentose phosphate pathway and cancer.
Trends Biochem Sci
; 39(8): 347-54, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-25037503
9.
Hexokinase 2 as a novel selective metabolic target for rheumatoid arthritis.
Ann Rheum Dis
; 77(11): 1636-1643, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30061164
10.
AMPK regulates NADPH homeostasis to promote tumour cell survival during energy stress.
Nature
; 485(7400): 661-5, 2012 May 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-22660331
11.
Akt as a target for cancer therapy: more is not always better (lessons from studies in mice).
Br J Cancer
; 117(2): 159-163, 2017 Jul 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-28557977
12.
Akt1 promotes stimuli-induced endothelial-barrier protection through FoxO-mediated tight-junction protein turnover.
Cell Mol Life Sci
; 73(20): 3917-33, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27113546
13.
Akt-dependent Skp2 mRNA translation is required for exiting contact inhibition, oncogenesis, and adipogenesis.
EMBO J
; 31(5): 1134-46, 2012 Mar 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-22307088
14.
Evidence for heightened hexokinase II immunoexpression in hepatocyte dysplasia and hepatocellular carcinoma.
Dig Dis Sci
; 60(2): 420-6, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25381201
15.
MADD is a downstream target of PTEN in triggering apoptosis.
J Cell Biochem
; 115(2): 261-70, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24038283
16.
Combination of oxidative stress and FOXM1 inhibitors induces apoptosis in cancer cells and inhibits xenograft tumor growth.
Am J Pathol
; 183(1): 257-65, 2013 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-23665201
17.
The Akt1 isoform is required for optimal IFN-ß transcription through direct phosphorylation of ß-catenin.
J Immunol
; 189(6): 3104-11, 2012 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22904301
18.
Akt deficiency impairs normal cell proliferation and suppresses oncogenesis in a p53-independent and mTORC1-dependent manner.
Cancer Cell
; 10(4): 269-80, 2006 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-17045205
19.
ROS inhibitor N-acetyl-L-cysteine antagonizes the activity of proteasome inhibitors.
Biochem J
; 454(2): 201-8, 2013 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23772801
20.
Emerging targets in lipid metabolism for cancer therapy.
Trends Pharmacol Sci
; 2024 May 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-38762377