Detalhe da pesquisa
1.
CRISPR-Cas9 recognition of enzymatically synthesized base-modified nucleic acids.
Nucleic Acids Res
; 51(4): 1501-1511, 2023 02 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-36611237
2.
Characterization of an HNA aptamer suggests a non-canonical G-quadruplex motif.
Nucleic Acids Res
; 51(15): 7736-7748, 2023 08 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-37439359
3.
Cryo-EM structures of wild-type and E138K/M184I mutant HIV-1 RT/DNA complexed with inhibitors doravirine and rilpivirine.
Proc Natl Acad Sci U S A
; 119(30): e2203660119, 2022 07 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-35858448
4.
Impact of Single Acyclic Phosphonate Nucleotide (ZNA) Modifications on DNA Duplex Stability.
Chemistry
; : e202401254, 2024 Apr 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-38687344
5.
Crystallographic analysis of engineered polymerases synthesizing phosphonomethylthreosyl nucleic acid.
Nucleic Acids Res
; 50(17): 9663-9674, 2022 09 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-36124684
6.
Amino-acyl tXNA as inhibitors or amino acid donors in peptide synthesis.
Nucleic Acids Res
; 50(20): 11415-11425, 2022 11 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36350642
7.
Conformational Morphing by a DNA Analogue Featuring 7-Deazapurines and 5-Halogenpyrimidines and the Origins of Adenine-Tract Geometry.
Biochemistry
; 62(19): 2854-2867, 2023 10 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-37694722
8.
Controlled E. coli Aggregation Mediated by DNA and XNA Hybridization.
Chembiochem
; 24(15): e202300191, 2023 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37119472
9.
Synthesis of mizoribine prodrugs and their in vivo evaluation as immunosuppressive agents.
Bioorg Med Chem Lett
; 95: 129490, 2023 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37770001
10.
Synthesis and anti-SARS-CoV-2 evaluation of lipid prodrugs of ß-D-N4-hydroxycytidine (NHC) and a 3'-fluoro-substituted analogue of NHC.
Bioorg Chem
; 135: 106527, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37031504
11.
In Vivo Assembly and Expression of DNA Containing Non-canonical Bases in the Yeast Saccharomyces cerevisiae.
Chembiochem
; 23(11): e202200060, 2022 06 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35322918
12.
Chimeric siRNAs with chemically modified pentofuranose and hexopyranose nucleotides: altritol-nucleotide (ANA) containing GalNAc-siRNA conjugates: in vitro and in vivo RNAi activity and resistance to 5'-exonuclease.
Nucleic Acids Res
; 48(8): 4028-4040, 2020 05 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32170309
13.
Identification of Polyphenol Derivatives as Novel SARS-CoV-2 and DENV Non-Nucleoside RdRp Inhibitors.
Molecules
; 28(1)2022 Dec 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-36615354
14.
Stable Hairpin Structures Formed by Xylose-Based Nucleic Acids.
Chembiochem
; 22(9): 1638-1645, 2021 05 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33427360
15.
Catalysts from synthetic genetic polymers.
Nature
; 518(7539): 427-30, 2015 Feb 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-25470036
16.
Highly stable hexitol based XNA aptamers targeting the vascular endothelial growth factor.
Nucleic Acids Res
; 47(10): 4927-4939, 2019 06 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30968117
17.
Kinetic analysis of N-alkylaryl carboxamide hexitol nucleotides as substrates for evolved polymerases.
Nucleic Acids Res
; 47(5): 2160-2168, 2019 03 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-30698800
18.
Rational design of an XNA ligase through docking of unbound nucleic acids to toroidal proteins.
Nucleic Acids Res
; 47(13): 7130-7142, 2019 07 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-31334814
19.
The Network of Replication, Transcription, and Reverse Transcription of a Synthetic Genetic Cassette.
Angew Chem Int Ed Engl
; 60(8): 4175-4182, 2021 02 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-33142013
20.
Orthogonal Genetic Systems.
Chembiochem
; 21(10): 1408-1411, 2020 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31889390