Detalhe da pesquisa
1.
Preclinical exploration of combined glucagon inhibition and liver-preferential insulin for treatment of diabetes using in vitro assays and rat and mouse models.
Diabetologia
; 66(2): 376-389, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36404376
2.
A High-Affinity "Synthavidin" Receptor for Squaraine Dyes.
Angew Chem Int Ed Engl
; 62(48): e202314373, 2023 Nov 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-37816075
3.
Structural Insight into the Self-Assembly of a Pharmaceutically Optimized Insulin Analogue Obtained by Small-Angle X-ray Scattering.
Mol Pharm
; 17(8): 2809-2820, 2020 08 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32579369
4.
Chemo- and Regioselective Ethynylation of Tryptophan-Containing Peptides and Proteins.
Chemistry
; 22(5): 1572-6, 2016 Jan 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-26634418
5.
Construction of Insulin 18-mer Nanoassemblies Driven by Coordination to Iron(II) and Zinc(II) Ions at Distinct Sites.
Angew Chem Int Ed Engl
; 55(7): 2378-81, 2016 Feb 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-26762534
6.
Investigation of the Physico-Chemical Properties that Enable Co-Formulation of Basal Insulin Degludec with Fast-Acting Insulin Aspart.
Pharm Res
; 32(7): 2250-8, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25563978
7.
Antagonistic Insulin Derivative Suppresses Insulin-Induced Hypoglycemia.
J Med Chem
; 66(11): 7516-7522, 2023 06 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37227951
8.
Perfluoroalkyl chains direct novel self-assembly of insulin.
Langmuir
; 28(1): 593-603, 2012 Jan 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-22129241
9.
Metal ion controlled self-assembly of a chemically reengineered protein drug studied by small-angle X-ray scattering.
Langmuir
; 28(33): 12159-70, 2012 Aug 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-22853842
10.
Design of the novel protraction mechanism of insulin degludec, an ultra-long-acting basal insulin.
Pharm Res
; 29(8): 2104-14, 2012 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-22485010
11.
Diboronate Fluorophore for the Measurement of l-Glucose and Other Carbohydrates and Its Interaction with Albumin.
ACS Omega
; 7(28): 24662-24668, 2022 Jul 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-35874210
12.
Controlled self-assembly of re-engineered insulin by Fe(II).
Chemistry
; 17(26): 7198-204, 2011 Jun 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-21626587
13.
Review: Glucose-sensitive insulin.
Mol Metab
; 46: 101107, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33137487
14.
Commemorating insulin's centennial: engineering insulin pharmacology towards physiology.
Trends Pharmacol Sci
; 42(8): 620-639, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34148677
15.
Engineering of Orally Available, Ultralong-Acting Insulin Analogues: Discovery of OI338 and OI320.
J Med Chem
; 64(1): 616-628, 2021 01 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-33356257
16.
Molecular Engineering of Insulin Icodec, the First Acylated Insulin Analog for Once-Weekly Administration in Humans.
J Med Chem
; 64(13): 8942-8950, 2021 07 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33944562
17.
Backbone cyclic insulin.
J Pept Sci
; 16(9): 473-9, 2010 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-20641002
18.
Factors Influencing Insulin Absorption Around Exercise in Type 1 Diabetes.
Front Endocrinol (Lausanne)
; 11: 573275, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-33193089
19.
Dually Reactive Long Recombinant Linkers for Bioconjugations as an Alternative to PEG.
ACS Omega
; 5(31): 19827-19833, 2020 Aug 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32803078
20.
Peripheral Mechanisms Mediating the Sustained Antidiabetic Action of FGF1 in the Brain.
Diabetes
; 68(3): 654-664, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30523024