Detalhe da pesquisa
1.
Inhibition of the renal apical sodium dependent bile acid transporter prevents cholemic nephropathy in mice with obstructive cholestasis.
J Hepatol
; 80(2): 268-281, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-37939855
2.
Acetaminophen overdose causes a breach of the blood-bile barrier in mice but not in rats.
Arch Toxicol
; 98(5): 1533-1542, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38466352
3.
Integrated data from intravital imaging and HPLC-MS/MS analysis reveal large interspecies differences in AFB1 metabolism in mice and rats.
Arch Toxicol
; 98(4): 1081-1093, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38436695
4.
Guided interactive image segmentation using machine learning and color-based image set clustering.
Bioinformatics
; 38(19): 4622-4628, 2022 09 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-35976110
5.
Interruption of bile acid uptake by hepatocytes after acetaminophen overdose ameliorates hepatotoxicity.
J Hepatol
; 77(1): 71-83, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35131407
6.
Intravital Dynamic and Correlative Imaging of Mouse Livers Reveals Diffusion-Dominated Canalicular and Flow-Augmented Ductular Bile Flux.
Hepatology
; 73(4): 1531-1550, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32558958
7.
Inhibition of cytochrome P450 enhances the nephro- and hepatotoxicity of ochratoxin A.
Arch Toxicol
; 96(12): 3349-3361, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36227364
8.
Colchicine overdose impairs the capacity of Kupffer cells to clear foreign particles and endotoxins.
Arch Toxicol
; 96(11): 3067-3076, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36102954
9.
Hypoalbuminemia affects the spatio-temporal tissue distribution of ochratoxin A in liver and kidneys: consequences for organ toxicity.
Arch Toxicol
; 96(11): 2967-2981, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35962801
10.
Subcellular spatio-temporal intravital kinetics of aflatoxin B1 and ochratoxin A in liver and kidney.
Arch Toxicol
; 95(6): 2163-2177, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34003344
11.
Quantitative analysis of hepatic macro- and microvascular alterations during cirrhogenesis in the rat.
J Anat
; 232(3): 485-496, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29205328
12.
Model Prediction and Validation of an Order Mechanism Controlling the Spatiotemporal Phenotype of Early Hepatocellular Carcinoma.
Bull Math Biol
; 80(5): 1134-1171, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29568983
13.
Model-guided identification of a therapeutic strategy to reduce hyperammonemia in liver diseases.
J Hepatol
; 64(4): 860-71, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26639393
14.
TiQuant: software for tissue analysis, quantification and surface reconstruction.
Bioinformatics
; 31(19): 3234-6, 2015 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26040455
15.
Integrated metabolic spatial-temporal model for the prediction of ammonia detoxification during liver damage and regeneration.
Hepatology
; 60(6): 2040-51, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24677161
16.
How predictive quantitative modelling of tissue organisation can inform liver disease pathogenesis.
J Hepatol
; 61(4): 951-6, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-24950483
17.
Protocols for staining of bile canalicular and sinusoidal networks of human, mouse and pig livers, three-dimensional reconstruction and quantification of tissue microarchitecture by image processing and analysis.
Arch Toxicol
; 88(5): 1161-83, 2014 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-24748404
18.
Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME.
Arch Toxicol
; 87(8): 1315-530, 2013 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-23974980
19.
Prediction and validation of cell alignment along microvessels as order principle to restore tissue architecture in liver regeneration.
Proc Natl Acad Sci U S A
; 107(23): 10371-6, 2010 Jun 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-20484673
20.
Digital twin demonstrates significance of biomechanical growth control in liver regeneration after partial hepatectomy.
iScience
; 26(1): 105714, 2023 Jan 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-36691615