Detalhe da pesquisa
1.
Genetic Inhibition of APOL1 Pore-Forming Function Prevents APOL1-Mediated Kidney Disease.
J Am Soc Nephrol
; 34(11): 1889-1899, 2023 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37798822
2.
APOL1 risk variants affect podocyte lipid homeostasis and energy production in focal segmental glomerulosclerosis.
Hum Mol Genet
; 30(3-4): 182-197, 2021 04 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-33517446
3.
APOL1 Genetic Variants Are Associated With Increased Risk of Coronary Atherosclerotic Plaque Rupture in the Black Population.
Arterioscler Thromb Vasc Biol
; 41(7): 2201-2214, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34039022
4.
APOL1 renal risk variants exacerbate podocyte injury by increasing inflammatory stress.
BMC Nephrol
; 21(1): 371, 2020 08 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-32854642
5.
PAN-AMPK Activation Improves Renal Function in a Rat Model of Progressive Diabetic Nephropathy.
J Pharmacol Exp Ther
; 371(1): 45-55, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31300612
6.
Development of indazole mineralocorticoid receptor antagonists and investigation into their selective late-stage functionalization.
Bioorg Med Chem Lett
; 29(14): 1854-1858, 2019 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31104995
7.
Therapeutics for APOL1 nephropathies: putting out the fire in the podocyte.
Nephrol Dial Transplant
; 32(suppl_1): i65-i70, 2017 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28391347
8.
Plasma Levels of Risk-Variant APOL1 Do Not Associate with Renal Disease in a Population-Based Cohort.
J Am Soc Nephrol
; 27(10): 3204-3219, 2016 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-27005919
9.
Small-molecule inhibition of glycogen synthase 1 for the treatment of Pompe disease and other glycogen storage disorders.
Sci Transl Med
; 16(730): eadf1691, 2024 Jan 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-38232139
10.
Mobilisation and analyses of publicly available SARS-CoV-2 data for pandemic responses.
Microb Genom
; 10(2)2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38358325
11.
Rapid detection and quantification of apolipoprotein L1 genetic variants and total levels in plasma by ultra-performance liquid chromatography/tandem mass spectrometry.
Rapid Commun Mass Spectrom
; 27(23): 2639-47, 2013 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24591025
12.
An analysis of CAF-1-interacting proteins reveals dynamic and direct interactions with the KU complex and 14-3-3 proteins.
J Biol Chem
; 286(12): 10876-87, 2011 Mar 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-21209461
13.
Effects of soluble guanylate cyclase stimulator on renal function in ZSF-1 model of diabetic nephropathy.
PLoS One
; 17(1): e0261000, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35085251
14.
Lack of APOL1 in proximal tubules of normal human kidneys and proteinuric APOL1 transgenic mouse kidneys.
PLoS One
; 16(6): e0253197, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34138902
15.
High-Throughput Screening to Identify Small Molecules That Selectively Inhibit APOL1 Protein Level in Podocytes.
SLAS Discov
; 26(9): 1225-1237, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34218698
16.
Molecular Profiling Reveals a Common Metabolic Signature of Tissue Fibrosis.
Cell Rep Med
; 1(4): 100056, 2020 07 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-33205063
17.
APOL1 renal risk variants promote cholesterol accumulation in tissues and cultured macrophages from APOL1 transgenic mice.
PLoS One
; 14(4): e0211559, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30998685
18.
MerCASBA: an updated and refined database of caspase substrates.
Apoptosis
; 18(3): 369-71, 2013 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-23334582
19.
APOL1 risk allele RNA contributes to renal toxicity by activating protein kinase R.
Commun Biol
; 1: 188, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30417125
20.
An integrin antagonist (MK-0429) decreases proteinuria and renal fibrosis in the ZSF1 rat diabetic nephropathy model.
Pharmacol Res Perspect
; 5(5)2017 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28971604